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GYN Translational Research Interests

Our team has a broad academic interest in the pathogenesis, diagnosis, therapeutic markers of neoplastic and pre-neoplastic lesions of gynecological organs - ovary, uterus, cervix, vulva and vagina. With available state-of-the-art molecular and genetic technology, we are currently undertaking focused investigations of the disease entities including gestational trophoblastic disease, endometrial cancers, uterine smooth muscle neoplasms and cervical glandular lesions. These research endeavors involve highly committed faculty and enthusiastic pathology trainees. A major effort in the gestational trophoblastic disease research program is to improve diagnostic accuracy by incorporating ancillary techniques including DNA genotyping and immunohistochemistry. Studies of endometrial cancers are aimed at identifying (1) early precursor lesions and (2) diagnostic, prognostic and predictive biomarkers. Many of the projects are designed and tailored to the long-term academic career development of individual members and frequently in close collaboration with the Yale Gynecologic Oncology group.


Bio Profile

Pei Hui, PhD, MD

Director GYN Pathology

Professor of Pathology and of Obstetrics, Gynecology and Reproductive Sciences

Director, Gynecologic Pathology

Clinical Director, Molecular Diagnostics Laboratory

Director, Gynecologic and Breast Pathology Fellowship Program.

Research Interests

Adnexal Diseases; Endometrial Neoplasms; Genotyping Techniques; Gestational Trophoblastic Disease; Gynecology; Molecular Diagnostic Techniques; Ovarian Neoplasms; Pathology; Uterine Cervical Neoplasms; Uterine Neoplasms; Vaginal Neoplasms; Vulvar Neoplasms

Dr. Hui is Professor in the Department of Pathology and Department of Obstetrics, Gynecology and Reproductive Sciences at Yale School of Medicine. He received combined anatomic and clinical pathology residency training at Yale-New Haven Hospital in 2000, followed by Oncological Pathology Fellowship training at MSKCC. He joined the pathology faculty at Yale in 2001 and became full professor in 2013. Dr. Hui is a board certified surgical pathologist with clinical specialty areas including...

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Bio Profile

Natalia Buza, MD

Associate Professor of Pathology

Associate Director of Gynecologic Pathology

Research Interests

Gestational Trophoblastic Disease; Morphological and Microscopic Findings; Ovarian Neoplasms; Pathological Conditions, Anatomical; Uterine Cervical Neoplasms; Uterine Neoplasms; Vulvar Neoplasms

Dr. Buza specializes in breast and gynecological pathology. She has been part of the Yale Pathology Breast and GYN team since 2010.

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Bio Profile

Serena Wong, MD

Assistant Professor of Pathology

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Additional Team Members

Pathology residents currently pursuing research projects within gynecologic pathology:

Agedi BotoJoshua JeantyRita Abi-Raad, Ryan Carr, and Ahmed Alomari

Collaboration with the members of the Yale Gynecologic Oncology group, lead by Dr. Thomas Rutherford.