Schwann cell spectrins modulate peripheral nerve myelination
Susuki K, Raphael AR, Ogawa Y, Stankewich MC, Peles E, Talbot WS, Rasband MN. Schwann cell spectrins modulate peripheral nerve myelination. Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 108: 8009-8014. PMID: 21518878, PMCID: PMC3093478, DOI: 10.1073/pnas.1019600108.Peer-Reviewed Original ResearchConceptsSchwann cell cytoskeletonCell cytoskeletonΒII spectrinSubmembranous cytoskeletal proteinsNeuron-glia interactionsEfficient action potential propagationSchwann cellsMembrane proteinsCytoskeletal rearrangementsLoss of spectrinCytoskeletal proteinsNectin-like proteinsCell shapeContact sitesF-actinPeripheral nerve myelinationSpectrinPeripheral nerve developmentΑII-spectrinCytoskeletonProteinNerve myelinationNerve developmentMotor nervesCells