2002
p53 Mutations as Tumor Markers in Fine Needle Aspirates of Palpable Breast Masses
Dillon DA, Hipolito E, Zheng K, Rimm DL, Costa JC. p53 Mutations as Tumor Markers in Fine Needle Aspirates of Palpable Breast Masses. Acta Cytologica 2002, 46: 841-847. PMID: 12365217, DOI: 10.1159/000327057.Peer-Reviewed Original ResearchMeSH KeywordsAbscessAdenocarcinomaAdultAgedAged, 80 and overAmino Acid SubstitutionBiomarkers, TumorBiopsy, NeedleBreast NeoplasmsCarcinoma, Ductal, BreastCodon, TerminatorCystsDNA Mutational AnalysisDNA, NeoplasmExonsFemaleFrameshift MutationGenes, p53GenotypeHumansMiddle AgedMutationPolymorphism, Single-Stranded ConformationalRetrospective StudiesConceptsFine needle aspiratesP53 exons 5Breast massesPolymerase chain reactionNeedle aspiratesP53 mutationsSingle-strand conformational polymorphism analysisSubsequent excisional biopsyPalpable breast massesPotential diagnostic utilityDefinitive cytologic diagnosisTumor cell markersExon 5Molecular diagnostic markersExcisional biopsyBenign cytologyBreast carcinomaSuspicious cytologyRetrospective analysisCytologic diagnosisTumor markersDiagnostic criteriaBiopsy tissueMorphologic diagnosisDiagnostic utility
1994
Papillary Variant of Low-grade Mucoepidermoid Carcinoma—An Unusual Bronchial Neoplasm: A Light Microscopic, Ultrastructural, and Immunohistochemical Study
Guillou L, De Luze P, Zysset F, Costa J. Papillary Variant of Low-grade Mucoepidermoid Carcinoma—An Unusual Bronchial Neoplasm: A Light Microscopic, Ultrastructural, and Immunohistochemical Study. American Journal Of Clinical Pathology 1994, 101: 269-274. PMID: 8135181, DOI: 10.1093/ajcp/101.3.269.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCarcinoma, MucoepidermoidCarcinoma, PapillaryFemaleHumansLung NeoplasmsNeoplasms, Multiple PrimaryConceptsLow-grade mucoepidermoid carcinomaMucoepidermoid carcinomaPapillary variantLow malignant potentialBronchial mucous gland adenomaElectron microscopic featuresMucous gland adenomaAppropriate therapyLower lobePapillary tumorsMalignant potentialImmunohistochemical studyDifferential diagnosisPostmortem examinationBronchial neoplasmsGland adenomaSurface epitheliumNeoplasm categoryLight microscopicCarcinomaMicroscopic featuresLesionsTumorsLobectomyPapillomas
1992
Stability of K-ras mutations throughout the natural history of human colorectal cancer
Losi L, Benhattar J, Costa J. Stability of K-ras mutations throughout the natural history of human colorectal cancer. European Journal Of Cancer 1992, 28: 1115-1120. PMID: 1627381, DOI: 10.1016/0959-8049(92)90468-h.Peer-Reviewed Original ResearchConceptsK-ras mutationsPrimary tumorRas mutationsNatural historyColorectal cancerTumor markersStable tumor markerHuman colorectal cancerDistant recurrenceRecurrent cancerRecurrent tumorsPolymerase chain reactionColorectal carcinomaCodon 12TumorsArchival tissueCancerChain reactionAllele-specific amplificationPatientsRecurrenceMarkersMutationsCarcinomaDisease