2023
PRAME immunohistochemistry can distinguish melanocytic pseudonests of lichenoid reactions from melanoma in situ
Roy S, Panse G, McNiff J. PRAME immunohistochemistry can distinguish melanocytic pseudonests of lichenoid reactions from melanoma in situ. Journal Of Cutaneous Pathology 2023, 50: 450-454. PMID: 36789669, DOI: 10.1111/cup.14407.Peer-Reviewed Original Research
2022
Microsecretory adenocarcinoma: Cutaneous counterpart of a newly described salivary gland tumor with recurrent MEF2C::SS18 fusion
Panse G. Microsecretory adenocarcinoma: Cutaneous counterpart of a newly described salivary gland tumor with recurrent MEF2C::SS18 fusion. Journal Of Cutaneous Pathology 2022, 50: 188-190. PMID: 36308392, DOI: 10.1111/cup.14349.Commentaries, Editorials and LettersMeSH KeywordsAdenocarcinomaBiomarkers, TumorHumansImmunohistochemistryMEF2 Transcription FactorsSalivary Gland NeoplasmsConceptsMicrosecretory adenocarcinomaSalivary gland tumorsGland tumorsLow-grade salivary gland tumorsHigh-grade featuresComplete surgical excisionUnique immunohistochemical profileMicrocystic tubulesCutaneous counterpartFibromyxoid stromaLocal recurrenceSurgical excisionHistopathological featuresIndolent tumorsImmunohistochemical profileClear cytoplasmUnique tumorOral cavityLuminal secretionsAccurate diagnosisTumorsSkinMolecular studiesVast majorityAdenocarcinoma
2017
Well‐differentiated neuroendocrine tumors in skin: Terminology and diagnostic utility of cytokeratin 5/6 and p63
Panse G, Cowper SE, Leffell DJ, Pulitzer M, Ko CJ. Well‐differentiated neuroendocrine tumors in skin: Terminology and diagnostic utility of cytokeratin 5/6 and p63. Journal Of Cutaneous Pathology 2017, 44: 557-562. PMID: 28417484, DOI: 10.1111/cup.12952.Peer-Reviewed Original ResearchConceptsCutaneous adnexal neoplasmsAdnexal neoplasmsNeuroendocrine tumorsAdnexal tumorsBenign skin adnexal tumorCutaneous adnexal tumorsAggressive metastatic diseaseLow-grade tumorsSkin adnexal tumorsMajority of casesMetastatic diseaseMetastatic adenocarcinomaCarcinoid tumorsCytokeratin 5/6Diagnostic challengeDifferential diagnosisImmunohistochemical stainsCK5/6Diagnostic utilityPrimary siteTumorsNeoplasmsFirst signWDNETsP63The role of phosphorylated signal transducer and activator of transcription 3 (pSTAT3) in peripheral nerve sheath tumours
Panse G, Leung CH, Ingram DR, Wani K, Torres KE, Lin H, Lazar AJ, Wang W. The role of phosphorylated signal transducer and activator of transcription 3 (pSTAT3) in peripheral nerve sheath tumours. Histopathology 2017, 70: 946-953. PMID: 27992966, DOI: 10.1111/his.13154.Peer-Reviewed Original ResearchConceptsMalignant peripheral nerve sheath tumorDisease-specific overall survivalEvent-free survivalPrimary malignant peripheral nerve sheath tumorPeripheral nerve sheath tumorsWorse event-free survivalKaplan-Meier methodNegative prognostic factorNerve sheath tumorsLog-rank testPeripheral nerve sheathParaffin-embedded tissue microarrayPhosphorylated STAT3 expressionPhosphorylated signal transducerMetastatic diseaseOverall survivalPrognostic factorsSheath tumorsAggressive diseaseNerve sheathPro-oncogenic transcription factorPrimary tumorDisease onsetTissue microarrayImmunohistochemical analysis