Narendra Wajapeyee, PhD

Associate Professor of Pathology

Research Interests

Genetics; Carcinoma, Hepatocellular; Lung Neoplasms; Melanoma; Pancreatic Neoplasms; Pathology; Disease Progression; Hematologic Neoplasms; Carcinogenesis; Phenomena and Processes

Research Organizations

Pathology: Pathology Research | Wajapeyee Lab

Faculty Research

Liver Center

Obesity Research Working Group

Yale Cancer Center: Signal Transduction

Office of Cooperative Research

Research Summary

Cancer is a complex disease and typically involves multiple gene-specific and global genetic and epigenetic changes in human genome. The major classes of genes that have been causally linked to the process of tumorigenesis are  tumor suppressors, which act as a “brakes”, and oncogenes, which function as “accelerators” and typically promote cancer. Recently, non-coding RNAs such as miRNAs and long non-coding RNAs are also linked to cancer, wherein they can either promote or inhibit cancer cell growth. The focus of our lab is to understand the mechanisms of genetic and epigenetic regulation of cancer initiation and progression and translating this understanding for early detection and treatment of human cancers. We use melanoma, pancreatic cancer, lung cancer, hepatocellular carcinoma and hematological malignancies as model systems to study mechanism of tumor initiation and progression.

Specialized Terms: Genetic and epigenetic mechanisms of cancer initiation and progression

Selected Publications

Full List of PubMed Publications

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Contact Info

Narendra Wajapeyee, PhD
Lab Location
Lauder Hall
310 Cedar Street, Ste LH 306

New Haven, CT 06510
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Office Location
Lauder Hall
310 Cedar Street, Ste LH315A

New Haven, CT 06510
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Mailing Address
310 Cedar Street
PO Box 208023

New Haven, CT 06520-8023

Wajapeyee Lab