Video Cognitive Behavioral Therapy to Prevent Depression in Patients with Inflammatory Bowel Disease
November 27, 2021- 00:04Hello, my name is Monica Nurse Alice and
- 00:06today I will be discussing my thesis
- 00:09titled Video Cognitive Behavioral Therapy
- 00:12to prevent depression in patients
- 00:14with inflammatory bowel disease,
- 00:16depression and anxiety in dependently
- 00:18decreased the quality of life in patients
- 00:21with inflammatory bowel disease or IBD.
- 00:23Those with moderate to severe IBD
- 00:25have shown to have higher rates of
- 00:28depression and anxiety compared to
- 00:29those with mild or inactive IBD.
- 00:31Patients are recommended to seek treatment
- 00:33after mental health symptoms arise.
- 00:35However, studies show a low proportion
- 00:37of patients have access to psychiatric
- 00:40consultation and psychotherapy,
- 00:42and studies found a low rate of
- 00:45psychiatric referrals among IBD patients.
- 00:47Adults with moderate to severe
- 00:49depression at baseline have experienced
- 00:51benefits from CBT,
- 00:52researchers showed mixed results on
- 00:54the effectiveness of CBT and changing
- 00:56disease activity and mental health. Slash.
- 00:58Quality of life and adults with IBD.
- 01:01Multiple gaps of literature have
- 01:03been identified.
- 01:04Newly diagnosed IBD patients
- 01:05present with the greatest need for
- 01:08psychotherapeutic intervention,
- 01:10but there is a lack of efficacy
- 01:12trials of CBT in newly diagnosed IBD.
- 01:14Adults prior research studying CBT
- 01:16in adults with IBD have excluded
- 01:19those with active or moderate to
- 01:21severe IBD disease.
- 01:22When this subgroup may benefit the most
- 01:25from a psychotherapeutic intervention.
- 01:28Only traditional face to face or self-help
- 01:31computerized randomized control trials
- 01:33have been conducted in this population.
- 01:35There is a lack of randomized control
- 01:38trials using video based CBT as an
- 01:40intervention in adults with IBD.
- 01:42There is a need for more randomized
- 01:44control trials comparing the
- 01:46effectiveness and acceptance of
- 01:48video based therapist guided CBT.
- 01:50Two traditional face to face CBT
- 01:52past RCTs were underpowered due to
- 01:55low adherence and high attrition to
- 01:57traditional and even computerized CBT.
- 02:00We hope our,
- 02:01besides that recently diagnosed moderate
- 02:03to severe IBD adults with moderate
- 02:05to severe depression and or anxiety,
- 02:07aged 18 to 40 who are treated with CBT
- 02:10as an adverb and a standard of care,
- 02:12will have a statistically significant
- 02:14decrease in depression and or
- 02:16anxiety scores as measured by the
- 02:18hospital anxiety and depression scale
- 02:20from baseline to 12 week.
- 02:22Follow up in comparison to patients
- 02:24receiving standard of care.
- 02:26We hypothesize these results will be
- 02:28maintained three months after intervention.
- 02:30Completion.
- 02:30Our study will be a two arm,
- 02:33single blinded,
- 02:34randomized control trial.
- 02:35The study will comprise of randomization
- 02:37to a 12 week intervention or standard
- 02:40care with a six month follow up from
- 02:43start of intervention of both groups.
- 02:45The intervention will be a video based
- 02:47therapist guided 60 minute individual
- 02:50sessions of CBT administered via Zoom.
- 02:53The primary outcome will be change
- 02:55in depression slash anxiety as
- 02:57measured by heads in the secondary
- 02:59outcome will be changed in quality
- 03:00of life as measured by short form
- 03:0212A quality of Life survey.
- 03:05By utilizing video based CBT we hope
- 03:07to conduct an adequately powered
- 03:09study anticipating better adherence.
- 03:12Additionally,
- 03:12we plan to use objective measures
- 03:15to assess disease activity.
- 03:16Given the subjectiveness of
- 03:18self reported surveys,
- 03:19this can reveal more insight into the
- 03:22bidirectional relationship between
- 03:23depression, slash, anxiety and IBD.
- 03:25Because this study is novel use
- 03:28of video based CBT compared to
- 03:30standard care in the IBD population,
- 03:32it would be ideal to create a
- 03:34study looking at adults with mild,
- 03:36moderate and severe depression.
- 03:38Slash anxiety symptoms at
- 03:40baseline and inactive, mild,
- 03:42moderate and severe IBD.
- 03:45Participants may also have responded burden
- 03:47with the weekly survey questionnaires.
- 03:50With this study,
- 03:51we hope to find that video based CBT can
- 03:53prevent a secondary clinical diagnosis
- 03:55of depression and or anxiety which
- 03:58can prevent future hospitalizations
- 03:59and decrease health care costs.
- 04:01If the findings of the study
- 04:04improve depression and or anxiety,
- 04:06providers will have evidence that video
- 04:08based CBT can be recommended for this group.
- 04:12In where here we have a schedule of
- 04:14assessments with the two weekly surveys
- 04:16that we will be administering to measure
- 04:19depression and anxiety and quality of life.
- 04:21And then the objective measures we will
- 04:23use as well to assess disease severity.
- 04:26Lastly,
- 04:26we have our sample size
- 04:28calculation which shows a total
- 04:30sample size of 128 participants.
- 04:32Thank you so much for listening.