2015
The novel tumor angiogenic factor, adrenomedullin-2, predicts survival in pancreatic adenocarcinoma
Hollander LL, Guo X, Salem RR, H. CH. The novel tumor angiogenic factor, adrenomedullin-2, predicts survival in pancreatic adenocarcinoma. Journal Of Surgical Research 2015, 197: 219-224. PMID: 25982376, DOI: 10.1016/j.jss.2014.11.002.Peer-Reviewed Original ResearchConceptsMitogen-activated protein kinase/extracellular signal-regulated kinaseProtein kinase/extracellular signal-regulated kinaseExtracellular signal-regulated kinaseSignal-regulated kinaseTotal cellular levelsAdrenomedullin 2Tumor angiogenesis factorVascular endothelial growth factor 2Microarray technologyGrowth factor 2Cellular levelNovel therapeutic targetPancreatic cancer tissuesProtein expressionFactor 2Angiogenesis factorsTherapeutic targetTumor angiogenic factorsTumor angiogenesisAngiogenic rolePotential roleWorse histologic gradePossible roleCancer tissuesPancreas cancer
2014
Renalase
Guo X, Wang L, Velazquez H, Safirstein R, Desir GV. Renalase. Current Opinion In Nephrology & Hypertension 2014, 23: 513-518. PMID: 24992568, PMCID: PMC4383282, DOI: 10.1097/mnh.0000000000000044.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsEnzymatic functionType 1 diabetesMitogen-activated protein kinase pathwayNucleotide polymorphismsProtein kinase BProtein kinase pathwayCellular actionsPlasma membraneKinase pathwayKinase BPotential therapeutic utilityCertain single nucleotide polymorphismsEnzymatic propertiesIschemic strokeImmune modulatorsRenalase geneTherapeutic utilityCytoprotective effectsClinical implicationsRenalaseConsistent associationPotential roleDiabetesCytokines