Women’s Health Research at Yale funds studies on colon cancer, infections in pregnancy, and domestic violence
“Through our competitive peer review process, these three studies stood out as extremely promising opportunities to improve and even save lives,” said Dr. Carolyn M. Mazure, director of WHRY. “With these new grants, we continue to expand a broad scope of existing work to focus on questions vital to the health and well-being of millions of women, men, and children.”
Low Levels of Vitamin B12 in Pregnancy May Increase the Risk of Preterm Birth, Study Finds
Nutrition during pregnancy affects the growing fetus, and identifying appropriate nutritional supplementation in pregnancy has been a hot topic for decades. Vitamin B12 is an essential nutritional component found only in animal-derived products like meat, milk and eggs. Low intake of such products increases the risk of vitamin B12 deficiency. The proportion of pregnant women with vitamin B12 deficiency ranges from a small percentage in some Western countries, like Norway, to over two thirds in developing countries, such as India. In a newly published paper, all previous studies on effects of vitamin B12 levels in pregnancy were evaluated and their results pooled in a meta study. The question asked was whether vitamin B12 deficiency during pregnancy was harmful for the fetus?
Fetal BPA exposure in mice linked to estrogen-related diseases after adolescence
Low levels of BPA exposure may be considered safe, but new research published online in The FASEB Journal, suggests otherwise. In the report, researchers from Yale show that the genome is permanently altered in the uterus of mice that had been exposed to BPA during their fetal development. These changes were found to mainly affect genes that are regulated by estrogen and are implicated in the formation of estrogen-related diseases such as infertility, endometriosis, endometrial cancer, osteoporosis, prostate cancer, neurodegenerative disease, obesity and breast cancer.Source: medicalxpress.com
Stress linked to worse recovery in women after heart attack
Young and middle-aged women experience more stress than their male counterparts, which could contribute to worse recovery from acute myocardial infarction (AMI), according to new findings by Yale School of Medicine researchers and their colleagues.
For women with hysterectomies, estrogen may be a lifesaver after all
The widespread rejection of estrogen therapy after the 2002 Women’s Health Initiative (WHI) study has most likely led to almost 50,000 unnecessary deaths over the last 10 years among women aged 50 to 69 who have had a hysterectomy, Yale School of Medicine researchers reveal in a study published in the July 18 issue of the American Journal of Public Health.
Estrogen Improves Short Term Memory and Oral Reading in Midlife Postmenopausal Women, Yale Researchers Find
Midlife postmenopausal women who received daily treatment with estrogen showed improved oral reading and verbal memory performance, Yale School of Medicine researchers report in the September issue of the journal Menopause.
WHRY and Elevate Expand Help for Women and Families in Need
Recognizing the urgent need to ensure the health of women in our communities, Women’s Health Research at Yale and Elevate, the university’s health policy lab, are collaborating to deploy interventions grounded in the latest and most reliable research directly to women and families.
Research Begun by WHRY Continues to Show Possible Pathway to Derail Dementia
Research is revealing the mechanisms that underlie the role of estradiol in memory so that next generation treatments for Alzheimer's disease and other dementias can specifically target these mechanisms and avoid the potential for negative side effects of systemic estrogen therapy.