Association of gestational and childhood circulating C-peptide concentrations in the hyperglycemia and adverse pregnancy outcomes follow-up study
Rajamoorthi A, Zheng H, Skowronski A, Zork N, Reddy U, Tung P, Kupsco A, Gallagher D, Salem R, Leibel R, LeDuc C, Thaker V. Association of gestational and childhood circulating C-peptide concentrations in the hyperglycemia and adverse pregnancy outcomes follow-up study. Diabetes Research And Clinical Practice 2024, 220: 111967. PMID: 39716665, PMCID: PMC11840794, DOI: 10.1016/j.diabres.2024.111967.Peer-Reviewed Original ResearchConceptsOral glucose tolerance testC-peptide concentrationsC-peptideInsulin sensitivityCord bloodFollow-up studyInsulinogenic indexHOMA-IRCirculating C-peptide concentrationsCord blood C-peptideMaternal glucose concentrationsBlood C-peptideBMI z-scoreGlucose tolerance testPancreatic beta-cell developmentBeta-cell developmentGestational ageOGTT glucoseMaternal fastingAssociations of gestationalPubertal stageTolerance testInsulin resistanceZ-scoreMaternal covariatesDesign, rationale and protocol for Glycemic Observation and Metabolic Outcomes in Mothers and Offspring (GO MOMs): an observational cohort study
Group T, Scholtens D, LeBlanc E, Vesco K, Amy D, Bays K, Massimino S, Robinson S, Schell K, Walters G, Hillier T, Oshiro C, Cordero S, Howick C, Kim L, Martinez Y, Pishchalenko O, Wastlova V, Zork N, Mourad M, Lonier J, Reddy U, Acevedo J, Castillo J, Gomez M, Peguero B, Facco F, Feghali M, Bocan H, Stramowski S, Powe C, Edlow A, Barth W, Nathan D, Azevedo R, Baez A, Iroajanma C, Larkin M, Maya J, Michalopoulos C, Neamonitaki N, Thangthaeng N, Yee L, Lowe W, Grobman W, Szmuilowicz E, Aguirre A, Guevara E, Mallett G, Matos S, Tyagi S, Spadola A, Catalano P, Azimirad A, Werner E, Rouse D, Malloy M, Parra F, Sherr J, Merriam A, Bitterman S, Considine E, Leventhal J, Perley L, Rink L, Steffen A, Thompson B, Zgorski M, Steffes M, Arends V, Killeen A, Siddique J, Bustamante P, Cheung Y, Freeze C, Grott T, Kuang A, Tull M, Linder B. Design, rationale and protocol for Glycemic Observation and Metabolic Outcomes in Mothers and Offspring (GO MOMs): an observational cohort study. BMJ Open 2024, 14: e084216. PMID: 38851233, PMCID: PMC11163666, DOI: 10.1136/bmjopen-2024-084216.Peer-Reviewed Original ResearchConceptsLarge-for-gestational-age birth weightMetabolic outcomesLarge-for-gestational-ageDiagnosis of gestational diabetesOral glucose tolerance testAdverse pregnancy outcomesVanderbilt University Institutional Review BoardCourse of pregnancyObservational cohort studyGlucose tolerance testNational Institute of DiabetesDigestive and Kidney DiseasesGDM treatmentWeeks gestationDetect such abnormalitiesPerinatal outcomesGDM screeningInstitutional review boardGestational diabetesFirst-trimesterPregnancy outcomesEarly pregnancyGlucose abnormalitiesBirth weightPregnant adults
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