2017
Predictive Accuracy of Serial Transvaginal Cervical Lengths and Quantitative Vaginal Fetal Fibronectin Levels for Spontaneous Preterm Birth Among Nulliparous Women
Esplin M, Elovitz M, Iams J, Parker C, Wapner R, Grobman W, Simhan H, Wing D, Haas D, Silver R, Hoffman M, Peaceman A, Caritis S, Parry S, Wadhwa P, Foroud T, Mercer B, Hunter S, Saade G, Reddy U. Predictive Accuracy of Serial Transvaginal Cervical Lengths and Quantitative Vaginal Fetal Fibronectin Levels for Spontaneous Preterm Birth Among Nulliparous Women. Obstetric Anesthesia Digest 2017, 37: 204. DOI: 10.1097/01.aoa.0000527046.29057.df.Peer-Reviewed Original ResearchFetal fibronectin levelsCervical lengthPreterm deliveryFibronectin levelsProspective observational cohort studyTransvaginal cervical lengthObservational cohort studySpontaneous preterm birthSpontaneous preterm deliveryNulliparous pregnant womenLong-term health effectsSpontaneous premature birthHigher medical costsCohort studyFetal fibronectinNulliparous womenPreterm birthPremature birthPregnant womenCervicovaginal fluidSerial measurementsUniversal screeningMedical costsMajor causeHealth effects
2015
A Genome‐Wide Association Study of Early Spontaneous Preterm Delivery
Zhang H, Baldwin DA, Bukowski RK, Parry S, Xu Y, Song C, Andrews WW, Saade GR, Esplin MS, Sadovsky Y, Reddy UM, Ilekis J, Varner M, Biggio JR, Research F. A Genome‐Wide Association Study of Early Spontaneous Preterm Delivery. Genetic Epidemiology 2015, 39: 217-226. PMID: 25599974, PMCID: PMC4366311, DOI: 10.1002/gepi.21887.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthMaternal single nucleotide polymorphismsSPTB casesPreterm birthValidation cohortSingle nucleotide polymorphismsEarly spontaneous preterm deliveryP-valueTerm controlsTerm delivery controlsSpontaneous preterm deliveryMother-infant pairsCase-control studyIndependent validation cohortRace/ethnicityPreterm deliveryInfant morbidityMaternal ageControl groupMultiple testing adjustmentMultiple comparisonsCohortBirthNucleotide polymorphismsGenome-wide association studies