Progression of Gestational Subclinical Hypothyroidism and Hypothyroxinemia to Overt Hypothyroidism After Pregnancy: Pooled Analysis of Data from Two Randomized Controlled Trials
Varner M, Mele L, Casey B, Peaceman A, Reddy U, Wapner R, Thorp J, Saade G, Tita A, Rouse D, Sibai B, Costantine M, Mercer B, Caritis S, Bethesda. Progression of Gestational Subclinical Hypothyroidism and Hypothyroxinemia to Overt Hypothyroidism After Pregnancy: Pooled Analysis of Data from Two Randomized Controlled Trials. Thyroid 2024 PMID: 39028022, DOI: 10.1089/thy.2023.0616.Peer-Reviewed Original ResearchSubclinical hypothyroidismOvert hypothyroidismAssociated with higher ratesTPO levelsThyroid peroxidaseYear 5Gestational subclinical hypothyroidismNormal free T4Multicenter treatment trialThyroid replacement therapyYear of deliveryThyrotropin (TSHThyroid peroxidase levelsYear 1Randomized controlled trialsWeeks gestationPlacebo groupTSH valuesMaternal serumReplacement therapyFree T4Higher ratesHypothyroxinemiaThyroid functionHypothyroidismOptimizing Opioid Prescription Quantity After Cesarean Delivery
Smid M, Clifton R, Rood K, Srinivas S, Simhan H, Casey B, Longo M, Landau R, MacPherson C, Bartholomew A, Sowles A, Reddy U, Rouse D, Bailit J, Thorp J, Chauhan S, Saade G, Grobman W, Macones G. Optimizing Opioid Prescription Quantity After Cesarean Delivery. Obstetrics And Gynecology 2024, 144: 195-205. PMID: 38857509, PMCID: PMC11257794, DOI: 10.1097/aog.0000000000005649.Peer-Reviewed Original ResearchOpioid tabletsCesarean birthOpioid useHuman Development Maternal-Fetal Medicine Units NetworkMaternal-Fetal Medicine Units NetworkPrimary outcomeQuantity of opioid tabletsEunice Kennedy Shriver National Institute of Child HealthOpioid prescription protocolPostcesarean pain managementHistory of opioid useOpioid prescription quantitiesRandomized controlled noninferiority trialNational Institute of Child HealthInstitute of Child HealthPostcesarean analgesiaCesarean deliveryRandomized controlled trialsPain managementPrescription quantitiesFollow-upWeeks postdischargeNoninferiority trialDecision makingChild health