2015
The phenotype of spontaneous preterm birth: application of a clinical phenotyping tool
Manuck TA, Esplin MS, Biggio J, Bukowski R, Parry S, Zhang H, Huang H, Varner MW, Andrews W, Saade G, Sadovsky Y, Reddy UM, Ilekis J, Research E. The phenotype of spontaneous preterm birth: application of a clinical phenotyping tool. American Journal Of Obstetrics And Gynecology 2015, 212: 487.e1-487.e11. PMID: 25687564, PMCID: PMC4456184, DOI: 10.1016/j.ajog.2015.02.010.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthEarly spontaneous preterm birthInfection/inflammationDecidual hemorrhageGestational ageCervical insufficiencyPreterm birthWeeks' gestationPlacental dysfunctionWhite womenMaternal stressSingleton spontaneous preterm birthDelivery gestational ageFinal common pathwayAfrican American womenMaternal comorbiditiesPremature ruptureProspective studyPlanned analysisUterine distentionClinical dataMultiple possible causesGestationHemorrhageComprehensive classification system
2001
In vitro sealing of punctured fetal membranes: Potential treatment for midtrimester premature rupture of membranes
Reddy U, Shah S, Nemiroff R, Ballas S, Hyslop T, Chen J, Wapner R, Sciscione A. In vitro sealing of punctured fetal membranes: Potential treatment for midtrimester premature rupture of membranes. American Journal Of Obstetrics And Gynecology 2001, 185: 1090-1093. PMID: 11717639, DOI: 10.1067/mob.2001.117685.Peer-Reviewed Original ResearchConceptsMidtrimester premature ruptureAmniotic fluidPremature ruptureFetal membranesAmniotic membraneSignificant perinatal morbidityPrimary outcome variableSecond trimester pregnancySecond trimester amniotic fluidRank sum testPerinatal morbidityMedian timeTrimester pregnancyPuncture siteEffective treatmentPotential treatmentNeedle punctureOutcome variablesSum test