2023
Comparing population-based fetal growth standards in a US cohort
Gleason J, Reddy U, Chen Z, Grobman W, Wapner R, Steller J, Simhan H, Scifres C, Blue N, Parry S, Grantz K. Comparing population-based fetal growth standards in a US cohort. American Journal Of Obstetrics And Gynecology 2023, 231: 338.e1-338.e18. PMID: 38151220, PMCID: PMC11196385, DOI: 10.1016/j.ajog.2023.12.034.Peer-Reviewed Original ResearchComposite perinatal morbidityFetal growth standardsPerinatal morbidityNeonatal morbidityWorld Health OrganizationGrowth standardsEunice Kennedy Shriver National InstituteNulliparous Pregnancy Outcomes StudyHighest AUCComposite neonatal morbiditySubsequent neonatal morbidityU.S. clinical centersFetal growth restrictionRisk of morbidityRace/Management of pregnancyPregnancy Outcomes StudyAntenatal monitoringNulliparous womenFetal weightFirst trimesterVisit 2Visit 3US cohortClinical centersHypertension in Pregnancy and Adverse Outcomes Among Low-risk Nulliparous Women Expectantly Managed at or After 39 weeks: A Secondary Analysis of a Randomized Controlled Trial
Bartal M, Premkumar A, Rice M, Reddy U, Tita A, Silver R, El-Sayed Y, Wapner R, Rouse D, Saade G, Thorp J, Constantine M, Chien E, Casey B, Srinivas S, Swamy G, Simhan H. Hypertension in Pregnancy and Adverse Outcomes Among Low-risk Nulliparous Women Expectantly Managed at or After 39 weeks: A Secondary Analysis of a Randomized Controlled Trial. Obstetric Anesthesia Digest 2023, 43: 82-82. DOI: 10.1097/01.aoa.0000927856.60760.92.Peer-Reviewed Original ResearchLow-risk patientsLow-risk nulliparous womenHypertensive disordersMaternal morbidityMaternal outcomesNulliparous womenControlled TrialsWeeks' gestationAdverse outcomesLower riskSecondary analysisPregnancyPatientsHDPOutcomesRecent studiesHypertensionMorbidityGestationMortalityPrevalenceTrialsWeeksWomen
2022
Hypertension in pregnancy and adverse outcomes among low‐risk nulliparous women expectantly managed at or after 39 weeks: a secondary analysis of a randomised controlled trial
Bartal M, Premkumar A, Rice M, Reddy U, Tita ATN, Silver RM, El‐Sayed Y, Wapner R, Rouse DJ, Saade GR, Thorp JM, Costantine M, Chien EK, Casey BM, Srinivas SK, Swamy GK, Simhan HN, Health H. Hypertension in pregnancy and adverse outcomes among low‐risk nulliparous women expectantly managed at or after 39 weeks: a secondary analysis of a randomised controlled trial. BJOG An International Journal Of Obstetrics & Gynaecology 2022, 129: 1396-1403. PMID: 34927787, PMCID: PMC9207156, DOI: 10.1111/1471-0528.17059.Peer-Reviewed Original ResearchConceptsAdverse maternal outcomesLow-risk nulliparous womenHypertensive disordersMaternal outcomesSecondary outcomesNulliparous womenAdverse outcomesComposite adverse maternal outcomeIntensive care unit admissionSecondary analysisCare unit admissionSevere neonatal complicationsWeeks of gestationMode of deliveryNulliparous individualsMaternal compositeNeonatal complicationsPerinatal compositePostpartum infectionUnit admissionCaesarean deliveryExpectant managementPlacental abruptionVenous thromboembolismGestational agePericonceptional diet quality predicts glycemic control and gestational diabetes risk in nulliparous women
Milone G, Chung J, Haas D, Silver R, Grobman W, Simhan H, Saade G, Reddy U, Lindsay K. Periconceptional diet quality predicts glycemic control and gestational diabetes risk in nulliparous women. American Journal Of Obstetrics And Gynecology 2022, 226: s46-s47. DOI: 10.1016/j.ajog.2021.11.106.Peer-Reviewed Original Research
2021
Health Resource Utilization of Labor Induction Versus Expectant Management
Grobman W, Sandoval G, Reddy U, Tita A, Silver R, Mallett G, Hill K, Rice M, El-Sayed Y, Wapner R, Rouse D, Saade G, Thorp J, Chauhan S, Iams J, Chien E, Casey B, Gibbs R, Srinivas S, Swamy G, Simhan H, Macones G. Health Resource Utilization of Labor Induction Versus Expectant Management. Obstetric Anesthesia Digest 2021, 41: 34-34. DOI: 10.1097/01.aoa.0000732480.32100.cf.Peer-Reviewed Original ResearchExpectant managementElective inductionNulliparous womenLow-risk nulliparous womenHealth care resource utilizationHealth resource utilizationNeonatal respiratory morbidityElective labor inductionARRIVE trialDelivery admissionHypertensive disordersCesarean deliveryLabor inductionRespiratory morbidityWeeks postpartumTrialsManagement trialsWeeksWomenInductionCurrent studyResource utilizationAntepartumMorbidityPregnancy726 Fetal growth by ultrasound prior to the diagnosis of gestational diabetes mellitus in nulliparous women
Mahdasian-Miller A, Scifres C, Haas D, Grobman W, Silver R, Wing D, Saade G, Reddy U, Simhan H. 726 Fetal growth by ultrasound prior to the diagnosis of gestational diabetes mellitus in nulliparous women. American Journal Of Obstetrics And Gynecology 2021, 224: s455-s456. DOI: 10.1016/j.ajog.2020.12.749.Peer-Reviewed Original Research
2019
Labor Induction Versus Expectant Management in Low-Risk Nulliparous Women
Grobman W, Rice M, Reddy U, Tita A, Silver R, Mallett G, Hill K, Thom E, El-Sayed Y, Perez-Delboy A, Rouse D, Saade G, Boggess K, Chauhan S, Iams J, Chien E, Casey B, Gibbs R, Srinivas S, Swamy G, Simhan H, Macones G. Labor Induction Versus Expectant Management in Low-Risk Nulliparous Women. Obstetrical & Gynecological Survey 2019, 74: 7-9. DOI: 10.1097/01.ogx.0000550506.01685.a7.Peer-Reviewed Original Research
2018
Defining Failed Induction of Labor
Grobman W, Bailit J, Lai Y, Reddy U, Wapner R, Varner M, Thorp J, Leveno K, Caritis S, Prasad M, Tita A, Saade G, Sorokin Y, Rouse D, Blackwell S, Tolosa J. Defining Failed Induction of Labor. Obstetric Anesthesia Digest 2018, 38: 215. DOI: 10.1097/01.aoa.0000547313.79293.f8.Peer-Reviewed Original ResearchCervical funneling or intra‐amniotic debris and preterm birth in nulliparous women with midtrimester cervical length less than 30 mm
Saade G, Thom E, Grobman W, Iams J, Mercer B, Reddy U, Tita A, Rouse D, Sorokin Y, Wapner R, Leveno K, Blackwell S, Esplin M, Tolosa J, Thorp J, Caritis S, Vandorsten J, Network T. Cervical funneling or intra‐amniotic debris and preterm birth in nulliparous women with midtrimester cervical length less than 30 mm. Ultrasound In Obstetrics And Gynecology 2018, 52: 757-762. PMID: 29155504, PMCID: PMC5960623, DOI: 10.1002/uog.18960.Peer-Reviewed Original ResearchConceptsCervical funnelingMidtrimester cervical lengthCervical lengthPreterm birthWeeks' gestationNulliparous womenMedian cervical lengthSecondary cohort analysisNulliparous pregnant womenSecond trimester ultrasoundAsymptomatic nulliparous womenMultivariable adjustmentSingleton gestationsMulticenter trialMultivariable analysisTransvaginal ultrasoundSecond trimesterPregnant womenCohort analysisGestationWomenHigh rateWeeksUltrasoundLtReassessing the Duration of the Second Stage of Labor in Relation to Maternal and Neonatal Morbidity
Grantz K, Sundaram R, Ma L, Hinkle S, Berghella V, Hoffman M, Reddy U. Reassessing the Duration of the Second Stage of Labor in Relation to Maternal and Neonatal Morbidity. Obstetric Anesthesia Digest 2018, 38: 71. DOI: 10.1097/01.aoa.0000532263.77010.0d.Peer-Reviewed Original ResearchNeonatal morbidityInitial cesarean sectionMaternal febrile morbiditySecond-stage arrestMaternal-fetal medicineFebrile morbidityEpidural analgesiaCesarean sectionMultiparous womenNulliparous womenPostpartum hemorrhageVaginal birthAmerican CollegeMorbidityMortalityWomenPresent studyBirthHoursAnalgesiaEpiduralHemorrhagePatientsGynecologistsObstetriciansReassessing the Duration of the Second Stage of Labor in Relation to Maternal and Neonatal Morbidity
Grantz KL, Sundaram R, Ma L, Hinkle S, Berghella V, Hoffman MK, Reddy UM. Reassessing the Duration of the Second Stage of Labor in Relation to Maternal and Neonatal Morbidity. Obstetrics And Gynecology 2018, 131: 345-353. PMID: 29324600, PMCID: PMC5785437, DOI: 10.1097/aog.0000000000002431.Peer-Reviewed Original ResearchConceptsSpontaneous vaginal birthSecond stage durationVaginal birthNulliparous womenNeonatal complicationsNeonatal morbidityCesarean deliveryFetal heart rate tracingsFirst half hourPrior cesarean deliverySpontaneous vaginal deliveryWeeks of gestationHeart rate tracingsVertex birthsRetrospective cohortMultiparous womenSerious complicationsSerious morbidityVaginal deliveryMorbidityHalf hourLikelihood of birthComplicationsWomenBirth
2017
Predictive Accuracy of Serial Transvaginal Cervical Lengths and Quantitative Vaginal Fetal Fibronectin Levels for Spontaneous Preterm Birth Among Nulliparous Women
Esplin M, Elovitz M, Iams J, Parker C, Wapner R, Grobman W, Simhan H, Wing D, Haas D, Silver R, Hoffman M, Peaceman A, Caritis S, Parry S, Wadhwa P, Foroud T, Mercer B, Hunter S, Saade G, Reddy U. Predictive Accuracy of Serial Transvaginal Cervical Lengths and Quantitative Vaginal Fetal Fibronectin Levels for Spontaneous Preterm Birth Among Nulliparous Women. Obstetric Anesthesia Digest 2017, 37: 204. DOI: 10.1097/01.aoa.0000527046.29057.df.Peer-Reviewed Original ResearchFetal fibronectin levelsCervical lengthPreterm deliveryFibronectin levelsProspective observational cohort studyTransvaginal cervical lengthObservational cohort studySpontaneous preterm birthSpontaneous preterm deliveryNulliparous pregnant womenLong-term health effectsSpontaneous premature birthHigher medical costsCohort studyFetal fibronectinNulliparous womenPreterm birthPremature birthPregnant womenCervicovaginal fluidSerial measurementsUniversal screeningMedical costsMajor causeHealth effectsPredictive Accuracy of Serial Transvaginal Cervical Lengths and Quantitative Vaginal Fetal Fibronectin Levels for Spontaneous Preterm Birth Among Nulliparous Women
Esplin M, Elovitz M, Iams J, Parker C, Wapner R, Grobman W, Simhan H, Wing D, Haas D, Silver R, Hoffman M, Peaceman A, Caritis S, Parry S, Wadhwa P, Foroud T, Mercer B, Hunter S, Saade G, Reddy U. Predictive Accuracy of Serial Transvaginal Cervical Lengths and Quantitative Vaginal Fetal Fibronectin Levels for Spontaneous Preterm Birth Among Nulliparous Women. Obstetrical & Gynecological Survey 2017, 72: 397-399. DOI: 10.1097/ogx.0000000000000455.Peer-Reviewed Original ResearchMaternal and Neonatal Outcomes With Early Compared With Delayed Pushing Among Nulliparous Women
Yee L, Sandoval G, Bailit J, Reddy U, Wapner R, Varner M, Caritis S, Prasad M, Tita A, Saade G, Sorokin Y, Rouse D, Blackwell S, Tolosa J. Maternal and Neonatal Outcomes With Early Compared With Delayed Pushing Among Nulliparous Women. Obstetric Anesthesia Digest 2017, 37: 98-99. DOI: 10.1097/01.aoa.0000515771.11264.4b.Peer-Reviewed Original Research
2015
The association of beta‐2 adrenoceptor genotype with short‐cervix mediated preterm birth: a case–control study
Miller R, Smiley R, Thom E, Grobman W, Iams J, Mercer B, Saade G, Tita A, Reddy U, Rouse D, Sorokin Y, Blackwell S, Esplin, Tolosa J, Caritis, Network E. The association of beta‐2 adrenoceptor genotype with short‐cervix mediated preterm birth: a case–control study. BJOG An International Journal Of Obstetrics & Gynaecology 2015, 122: 1387-1394. PMID: 25600430, PMCID: PMC4508241, DOI: 10.1111/1471-0528.13243.Peer-Reviewed Original ResearchConceptsShort cervixCervical lengthAR genotypeMaternal-Fetal Medicine Units NetworkEunice Kennedy Shriver National InstituteNormal cervical lengthShort cervical lengthShort cervix groupPreterm birth riskCase-control studyRace/ethnicitySpontaneous PTBNulliparous womenPregnancy outcomesPreterm birthTransvaginal sonogramsPrimary outcomePTB riskSecond trimesterAncillary studiesChild healthBirth riskCervixAdrenoceptor genotypeControl group
2011
Contemporary Patterns of Spontaneous Labor With Normal Neonatal Outcomes
Zhang J, Landy H, Branch W, Burkman R, Haberman S, Gregory K, Hatjis C, Ramirez M, Bailit J, Gonzalez-Quintero V, Hibbard J, Hoffman M, Kominiarek M, Learman L, Van Veldhuisen P, Troendle J, Reddy U. Contemporary Patterns of Spontaneous Labor With Normal Neonatal Outcomes. Obstetrical & Gynecological Survey 2011, 66: 132-133. DOI: 10.1097/ogx.0b013e31821685d0.Peer-Reviewed Original ResearchNormal neonatal outcomeNulliparous womenCervical dilationNeonatal outcomesMultiparous womenSpontaneous onsetAdequate uterine contractionDuration of laborSingleton term pregnanciesAverage labor curvesContemporary obstetric populationElectronic medical recordsInterval-censored regressionRepeated-measures analysisLabor arrestAbnormal laborEpidural analgesiaObstetric populationSpontaneous laborTerm pregnancyVaginal deliveryVertex presentationUterine contractionsClinical centersMedical records