2023
Sodium intake and the development of hypertensive disorders of pregnancy
Bank T, Grasch J, Chung J, Mercer B, McNeil R, Parry S, Saade G, Shanks A, Silver R, Simhan H, Yee L, Reddy U, Grobman W, Frey H. Sodium intake and the development of hypertensive disorders of pregnancy. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101166. PMID: 37741626, DOI: 10.1016/j.ajogmf.2023.101166.Peer-Reviewed Original ResearchConceptsHypertensive disordersHigh sodium intakeSodium intakeChronic hypertensionNonpregnant populationLow platelet count syndromeNeonatal intensive care unitNulliparous Pregnancy Outcomes StudyElevated liver enzymesGestational age neonatesFood frequency questionnaireLow sodium intakeIncidence risk ratioIntensive care unitWeeks of gestationPregnancy Outcomes StudyLack of associationChi-square testGestational hypertensionNeonatal outcomesNonpregnant stateSodium restrictionFrequency questionnairePreterm birthSingleton pregnanciesRisk factors and perinatal outcomes for persistent placenta previa in nulliparas
Post R, Chang J, Ziogas A, Crosland B, Silver R, Haas D, Grobman W, Saade G, Reddy U, Simhan H, Chung J. Risk factors and perinatal outcomes for persistent placenta previa in nulliparas. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101136. PMID: 37598887, DOI: 10.1016/j.ajogmf.2023.101136.Peer-Reviewed Original ResearchPersistent placenta previaPlacenta previaMidtrimester ultrasoundRisk factorsPrevious pregnancyCesarean deliveryMaternal ageNulliparous Pregnancy Outcomes StudyLower neonatal birthweightOlder maternal agePrevious cesarean deliveryProspective cohort studyPregnancy Outcomes StudySignificant risk factorsMultivariate logistic regressionNulliparous individualsPrevious dilationNeonatal birthweightNeonatal outcomesPerinatal outcomesPreterm deliveryBaseline characteristicsCohort studyThird trimesterAntepartum admissionsAssociation between Sleep Disordered Breathing and Neonatal Outcomes in Nulliparous Individuals
Delgado A, Kendle A, Randis T, Donda K, Salemi J, Facco F, Parker C, Reddy U, Silver R, Basner R, Chung J, Schubert F, Pien G, Redline S, Parry S, Grobman W, Zee P, Louis J. Association between Sleep Disordered Breathing and Neonatal Outcomes in Nulliparous Individuals. American Journal Of Perinatology 2023, 41: e2418-e2426. PMID: 37380034, DOI: 10.1055/a-2115-0147.Peer-Reviewed Original ResearchSleep-disordered breathingAdverse neonatal outcomesNeonatal outcomesPrimary outcomeRisk ratioApnea-hypopnea indexRespiratory distress syndromeBody mass indexEvents/hConfidence intervalsSleep Disordered BreathingLog-binomial regressionNulliparous individualsHome sleep studiesChronic hypertensionNeonatal morbidityNew onsetPregestational diabetesComposite outcomeRespiratory supportTransient tachypneaDistress syndromeGestational ageMass indexMaternal riskFetal growth restriction and small for gestational age as predictors of neonatal morbidity: which growth nomogram to use?
Leon-Martinez D, Lundsberg L, Culhane J, Zhang J, Son M, Reddy U. Fetal growth restriction and small for gestational age as predictors of neonatal morbidity: which growth nomogram to use? American Journal Of Obstetrics And Gynecology 2023, 229: 678.e1-678.e16. PMID: 37348779, DOI: 10.1016/j.ajog.2023.06.035.Peer-Reviewed Original ResearchConceptsNeonatal composite outcomeComposite outcomeFetal growth restrictionGestational ageFetal weightWeeks of gestationPositive likelihood ratioGrowth restrictionNonanomalous singleton pregnanciesPoor neonatal outcomeRetrospective cohort studySingle academic centerWeeks of deliveryDays of deliveryFetal growth referencesElectronic medical recordsProportion of fetusesLikelihood ratioNeonatal morbidityNeonatal outcomesPerinatal outcomesCohort studySingleton pregnanciesNeonatal dataMedical recordsShort-term neonatal outcomes of pregnancies complicated by maternal obesity
Dinsmoor M, Ugwu L, Bailit J, Reddy U, Wapner R, Varner M, Thorp J, Caritis S, Prasad M, Tita A, Saade G, Sorokin Y, Rouse D, Blackwell S, Tolosa J, Network E. Short-term neonatal outcomes of pregnancies complicated by maternal obesity. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 100874. PMID: 36690180, PMCID: PMC10065915, DOI: 10.1016/j.ajogmf.2023.100874.Peer-Reviewed Original ResearchConceptsComposite neonatal morbidityNeonatal outcomesBody mass indexWeeks of gestationMaternal obesityNeonatal morbidityMorbid obesityMass indexReference groupIntraventricular hemorrhage grade 3Short-term neonatal outcomesCohort of deliveriesComposite neonatal outcomeSuper morbid obesityHypoxic-ischemic encephalopathyPrevious cesarean deliveryRespiratory distress syndromeChronic hypertensionPreterm deliveryBaseline characteristicsCesarean deliveryComposite outcomeMaternal heightMaternal preeclampsiaObese patients
2022
Treatment for Mild Chronic Hypertension During Pregnancy
Tita A, Szychowski J, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes B, Bell J, Aagaard K, Edwards R, Gibson K, Haas D, Plante L, Metz T, Casey B, Esplin S, Longo S, Hoffman M, Saade G, Hoppe K, Foroutan J, Tuuli M, Owens M, Simhan H, Frey H, Rosen T, Palatnik A, Baker S, August P, Reddy U, Kinzler W, Su E, Krishna I, Nguyen N, Norton M, Skupski D, El-Sayed Y, Ogunyemi D, Galis Z, Harper L, Ambalavanan N, Geller N, Oparil S, Cutter G, Andrews W. Treatment for Mild Chronic Hypertension During Pregnancy. Obstetrical & Gynecological Survey 2022, 77: 634-636. DOI: 10.1097/01.ogx.0000899456.24100.71.Peer-Reviewed Original ResearchHypertension During PregnancyAcute kidney injuryAdverse neonatal outcomesChronic hypertensionKidney injuryMaternal outcomesNeonatal outcomesPlacental abruptionPreterm birthHeart failureMaternal deathsGestational agePerinatal deathPulmonary edemaPregnancyBlack womenDeathOutcomesHypertensionAbruptionPreeclampsiaEdemaInjuryStrokeWomen
2021
Outcomes in Twins Compared With Singletons Subsequent to Preterm Prelabor Rupture of Membranes
Bartal M, Ugwu LG, Grobman WA, Bailit JL, Reddy UM, Wapner RJ, Varner MW, Thorp JM, Caritis SN, Prasad M, Tita ATN, Saade GR, Rouse DJ. Outcomes in Twins Compared With Singletons Subsequent to Preterm Prelabor Rupture of Membranes. Obstetrics And Gynecology 2021, 138: 725-731. PMID: 34619719, PMCID: PMC8542618, DOI: 10.1097/aog.0000000000004561.Peer-Reviewed Original ResearchMeSH KeywordsAdultChorioamnionitisCohort StudiesEndometritisEnterocolitis, NecrotizingFemaleFetal Membranes, Premature RuptureGestational AgeHumansInfant, NewbornInfant, PrematureOutcome Assessment, Health CarePerinatal MortalityPregnancyPregnancy OutcomePregnancy, TwinPremature BirthSepsisVenous ThromboembolismWound InfectionYoung AdultConceptsComposite maternal morbidityPreterm prelabor ruptureWeeks of gestationNeonatal morbidityPreterm PROMSingleton gestationsMaternal morbidityPrelabor ruptureTwin gestationsOdds ratioComposite major neonatal morbidityComposite neonatal morbidityMajor neonatal morbidityMedian gestational ageMedian latency periodMajor fetal anomaliesAdjusted odds ratioCoprimary outcomesObstetric cohortNeonatal outcomesTwin neonatesGestational agePotential confoundersFetal anomaliesMorbidityMaternal and Neonatal Outcomes in Nulliparous Participants Undergoing Labor Induction by Cervical Ripening Method
Andrikopoulou M, Bushman E, Rice M, Grobman W, Reddy U, Silver R, El-Sayed Y, Rouse D, Saade G, Thorp J, Chauhan S, Costantine M, Chien E, Casey B, Srinivas S, Swamy G, Simhan H. Maternal and Neonatal Outcomes in Nulliparous Participants Undergoing Labor Induction by Cervical Ripening Method. American Journal Of Perinatology 2021, 40: 1061-1070. PMID: 34352922, PMCID: PMC8817048, DOI: 10.1055/s-0041-1732379.Peer-Reviewed Original ResearchConceptsAdverse neonatal outcomesCervical ripeningNeonatal outcomesLabor inductionNulliparous participantsComposite outcomeAdverse maternal outcomesCervical ripening methodsMaternal composite outcomeNeonatal composite outcomeLow-risk womenLength of laborConcurrent oxytocinCoprimary outcomesNeonatal compositeExpectant managementMaternal outcomesCesarean deliverySecondary outcomesFetal demisePatient characteristicsMultivariable analysisCervical dilationLower riskSecondary analysisMaternal outcomes and risk factors for COVID-19 severity among pregnant women
Vouga M, Favre G, Martinez-Perez O, Pomar L, Acebal LF, Abascal-Saiz A, Hernandez MRV, Hcini N, Lambert V, Carles G, Sichitiu J, Salomon L, Stirnemann J, Ville Y, de Tejada BM, Goncé A, Hawkins-Villarreal A, Castillo K, Solsona EG, Trigo L, Cleary B, Geary M, Bartels H, Al-Kharouf F, Malone F, Higgins M, Keating N, Knowles S, Poncelet C, Ribeiro-do-Valle CC, Surita F, Dantas-Silva A, Borrelli C, Luz AG, Fuenzalida J, Carvajal J, Canales MG, Hernandez O, Grechukhina O, Ko AI, Reddy U, Figueiredo R, Moucho M, Pinto PV, De Luca C, De Santis M, de Campos DA, Martins I, Garabedian C, Subtil D, Bohrer B, Da Rocha Oppermann ML, Wender MCO, Schuler-Faccini L, Sanseverino MTV, Giugliani C, Friedrich L, Scherer MH, Mottet N, Ducarme G, Pelerin H, Moreau C, Breton B, Quibel T, Rozenberg P, Giannoni E, Granado C, Monod C, Mueller D, Hoesli I, Bassler D, Heldstab S, Kölble NO, Sentilhes L, Charvet M, Deprest J, Richter J, Van der Veeken L, Eggel-Hort B, Plantefeve G, Derouich M, Calvache AJN, Lopez-Giron MC, Burgos-Luna JM, Escobar-Vidarte MF, Hecher K, Tallarek AC, Hadar E, Haratz KK, Amikam U, Malinger G, Maymon R, Yogev Y, Schäffer L, Toussaint A, Rossier MC, De Sa RAM, Grawe C, Aebi-Popp K, Radan AP, Raio L, Surbek D, Böckenhoff P, Strizek B, Kaufmann M, Bloch A, Boulvain M, Johann S, Heldstab SA, Bernasconi MT, Grant G, Feki A, Brochut AM, Giral M, Sedille L, Papadia A, Brugger RC, Weber B, Fischer T, Kahlert C, Saines KN, Cambou M, Kanellos P, Chen X, Yin M, Haessig A, Ackermann S, Baud D, Panchaud A. Maternal outcomes and risk factors for COVID-19 severity among pregnant women. Scientific Reports 2021, 11: 13898. PMID: 34230507, PMCID: PMC8260739, DOI: 10.1038/s41598-021-92357-y.Peer-Reviewed Original ResearchConceptsSevere maternal outcomesPregnant womenRisk factorsMaternal outcomesPulmonary comorbiditiesHypertensive disordersNeonatal outcomesSevere complicationsHigh riskSevere acute respiratory syndrome coronavirus 2Severe coronavirus disease-19Severe COVID-19 diseaseAcute respiratory syndrome coronavirus 2Neonatal intensive care unitSARS-CoV-2 infectionRespiratory syndrome coronavirus 2Immediate neonatal outcomeIntensive care unitSyndrome coronavirus 2COVID-19 severityCase-control studyCoronavirus disease-19SARS-CoV-2COVID-19 diseaseMaternal disease
2019
Early Preterm Preeclampsia Outcomes by Intended Mode of Delivery
Coviello E, Iqbal S, Grantz K, Huang C, Landy H, Reddy U. Early Preterm Preeclampsia Outcomes by Intended Mode of Delivery. Obstetric Anesthesia Digest 2019, 39: 187-188. DOI: 10.1097/01.aoa.0000603672.77426.4d.Peer-Reviewed Original ResearchSevere featuresEarly preterm deliveryEarly preterm preeclampsiaEarly preterm birthElevated liver enzymesSyndrome of hemolysisIntended modePreeclampsia outcomesNeonatal outcomesPregnant patientsPreterm deliveryPreterm preeclampsiaPreterm birthLow plateletsMaternal mortalityLiver enzymesPaucity of studiesPreeclampsiaOutcomesDeliveryEclampsiaMorbidityPatientsPregnancySyndromeNeonatal Outcomes of Elective Early-term Births After Demonstrated Fetal Lung Maturity
Tita A, Jablonski K, Bailit J, Grobman W, Wapner R, Reddy U, Varner M, Thorp J, Leveno K, Caritis S, Iams J, Saade G, Sorokin Y, Rouse D, Blackwell S, Tolosa J. Neonatal Outcomes of Elective Early-term Births After Demonstrated Fetal Lung Maturity. Obstetric Anesthesia Digest 2019, 39: 93-93. DOI: 10.1097/01.aoa.0000557681.76214.2f.Peer-Reviewed Original ResearchFetal lung maturity testingLung maturity testingEarly term birthEarly-term neonatesFetal lung maturityNeonatal outcomesMaturity testingLung maturityAdverse neonatal outcomesFull-term birthFull-term neonatesNeonatal morbidityRespiratory outcomesEarly deliveryAbsence of indicationsNeonatesBirthOutcomesRiskPretermMorbidityTestingDuration of Operative Vaginal Delivery and Adverse Obstetric Outcomes
Miller E, Lai Y, Bailit J, Reddy U, Wapner R, Varner M, Thorp J, Leveno K, Caritis S, Prasad M, Tita A, Saade G, Sorokin Y, Rouse D, Blackwell S, Tolosa J. Duration of Operative Vaginal Delivery and Adverse Obstetric Outcomes. American Journal Of Perinatology 2019, 37: 503-510. PMID: 30895577, PMCID: PMC6754310, DOI: 10.1055/s-0039-1683439.Peer-Reviewed Original ResearchConceptsComposite adverse neonatal outcomeAdverse neonatal outcomesOperative vaginal deliveryNeonatal outcomesVaginal deliveryMulticenter observational cohortAdverse obstetric outcomesSevere perineal lacerationsObstetric outcomesPerinatal outcomesObservational cohortPerineal lacerationsPrimary cohortForceps applicationPotential confoundersSecondary analysisStrong associationOutcomesWomenCohortDurationDeliveryLacerationConfoundersForcepsNeonatal Outcomes of Elective Early-term Births After Demonstrated Fetal Lung Maturity
Tita A, Jablonski K, Bailit J, Grobman W, Wapner R, Reddy U, Varner M, Thorp J, Leveno K, Caritis S, Iams J, Saade G, Sorokin Y, Rouse D, Blackwell S, Tolosa J. Neonatal Outcomes of Elective Early-term Births After Demonstrated Fetal Lung Maturity. Obstetrical & Gynecological Survey 2019, 74: 66-67. DOI: 10.1097/01.ogx.0000553099.70846.e7.Peer-Reviewed Original Research
2018
Defining Failed Induction of Labor
Grobman W, Bailit J, Lai Y, Reddy U, Wapner R, Varner M, Thorp J, Leveno K, Caritis S, Prasad M, Tita A, Saade G, Sorokin Y, Rouse D, Blackwell S, Tolosa J. Defining Failed Induction of Labor. Obstetric Anesthesia Digest 2018, 38: 215. DOI: 10.1097/01.aoa.0000547313.79293.f8.Peer-Reviewed Original ResearchNonmedically Indicated Induction in Morbidly Obese Women is Not Associated With an Increased Risk of Cesarean Delivery
Kawakita T, Iqbal S, Huang C, Reddy U. Nonmedically Indicated Induction in Morbidly Obese Women is Not Associated With an Increased Risk of Cesarean Delivery. Obstetric Anesthesia Digest 2018, 38: 125-126. DOI: 10.1097/01.aoa.0000542343.43890.b0.Peer-Reviewed Original ResearchInduction of laborMorbidly obese womenCesarean deliveryObese womenExpectant managementClass III obesityRetrospective cohort studyNormal-weight womenIndicated inductionMaternal comorbiditiesMorbid obesityNeonatal outcomesCohort studySecondary outcomesWeeks' gestationRisk factorsHigh prevalenceClass IIObesityWomenComorbiditiesInductionOutcomesDeliveryRisk
2017
Maternal and Neonatal Outcomes With Early Compared With Delayed Pushing Among Nulliparous Women
Yee L, Sandoval G, Bailit J, Reddy U, Wapner R, Varner M, Caritis S, Prasad M, Tita A, Saade G, Sorokin Y, Rouse D, Blackwell S, Tolosa J. Maternal and Neonatal Outcomes With Early Compared With Delayed Pushing Among Nulliparous Women. Obstetric Anesthesia Digest 2017, 37: 98-99. DOI: 10.1097/01.aoa.0000515771.11264.4b.Peer-Reviewed Original ResearchNeonatal Outcomes by Attempted Mode of Delivery and Obstetric Intervention for Pregnancies Affected by Spina Bifida [19R]
Spiliopoulos M, Iqbal S, Reddy U, Landy H, Huang C. Neonatal Outcomes by Attempted Mode of Delivery and Obstetric Intervention for Pregnancies Affected by Spina Bifida [19R]. Obstetrics And Gynecology 2017, 129: 188s. DOI: 10.1097/01.aog.0000514163.09127.5e.Peer-Reviewed Original ResearchImmediate neonatal outcomeNeonatal outcomesCesarean deliveryMode of deliveryVaginal deliverySpina bifidaInduced laborLabor induction groupRetrospective cohort studyPrevious cesarean deliveryInduction of laborMultivariable logistic regressionWeeks of gestationYears of ageSafe Labor studyNICU admissionCesarean sectionCohort studyRespiratory morbiditySingleton pregnanciesSpontaneous laborBreech deliveryGestational ageObstetric interventionsBirth traumaMaternal and Neonatal Outcomes by Mode of Delivery in Obese Women With a Previous Cesarean Section [5R]
Coviello E, Clark-Ganheart C, Huang C, Landy H, Iqbal S, Reddy U. Maternal and Neonatal Outcomes by Mode of Delivery in Obese Women With a Previous Cesarean Section [5R]. Obstetrics And Gynecology 2017, 129: 184s. DOI: 10.1097/01.aog.0000514150.02396.7a.Peer-Reviewed Original ResearchPrior cesarean deliveryDVT/PEMode of deliveryMaternal ICU admissionCesarean deliveryNeonatal outcomesObese womenPostpartum hemorrhageICU admissionObesity classDeep vein thrombosis/pulmonary embolismPlanned repeat cesarean deliveryVBAC success ratePrevious cesarean sectionRepeat cesarean deliveryTrial of laborClasses of obesityMultivariable logistic regressionSuccess rateLess womenHypertensive disordersMaternal outcomesSuccessful VBACCesarean sectionPulmonary embolism188: Neonatal outcomes for pregnancies complicated by fetal cardiac anomalies according to attempted route of delivery
Parikh L, Grantz K, Iqbal S, Huang C, Fries M, Landy H, Reddy U. 188: Neonatal outcomes for pregnancies complicated by fetal cardiac anomalies according to attempted route of delivery. American Journal Of Obstetrics And Gynecology 2017, 216: s122. DOI: 10.1016/j.ajog.2016.11.092.Peer-Reviewed Original Research652: Maternal and neonatal outcomes associated with non-medically indicated induction of labor at term compared with expectant management in morbidly obese women
Kawakita T, Iqbal S, Huang C, Reddy U. 652: Maternal and neonatal outcomes associated with non-medically indicated induction of labor at term compared with expectant management in morbidly obese women. American Journal Of Obstetrics And Gynecology 2017, 216: s383. DOI: 10.1016/j.ajog.2016.11.386.Peer-Reviewed Original Research