2024
Genetic polymorphisms associated with adverse pregnancy outcomes in nulliparas
Khan R, Guerrero R, Wapner R, Hahn M, Raja A, Salleb-Aouissi A, Grobman W, Simhan H, Silver R, Chung J, Reddy U, Radivojac P, Pe’er I, Haas D. Genetic polymorphisms associated with adverse pregnancy outcomes in nulliparas. Scientific Reports 2024, 14: 10514. PMID: 38714721, PMCID: PMC11076516, DOI: 10.1038/s41598-024-61218-9.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesAdverse pregnancy outcomesMulti-ancestry genome-wide association studyCluster of SNPsGestational diabetesPregnancy outcomesAdmixed AmericansNovel lociPregnancy lossAssociation studiesGenetic markersIncreased risk of pregnancy lossTRMU geneGenetic ancestryAssociated with gestational diabetesRisk of pregnancy lossSub-cohortProportion of pregnanciesCause of morbidityLociAssociation TestSNPsPreterm birthMaternal riskIncreased risk
2022
Association of a Mediterranean Diet Pattern With Adverse Pregnancy Outcomes Among US Women
Makarem N, Chau K, Miller E, Gyamfi-Bannerman C, Tous I, Booker W, Catov J, Haas D, Grobman W, Levine L, McNeil R, Merz C, Reddy U, Wapner R, Wong M, Bello N. Association of a Mediterranean Diet Pattern With Adverse Pregnancy Outcomes Among US Women. JAMA Network Open 2022, 5: e2248165. PMID: 36547978, PMCID: PMC9857221, DOI: 10.1001/jamanetworkopen.2022.48165.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesMediterranean diet patternTime of conceptionPregnancy outcomesDiet patternLower oddsAMED scoresGestational diabetesCohort studyUS womenLower riskRisk of APOsPrepregnancy body mass indexCardiovascular disease risk factorsSemiquantitative food frequency questionnaireAlternate Mediterranean diet scoreNulliparous Pregnancy Outcomes StudyLowest AMED scoresGestational age infantsDisease risk factorsDose-response associationFood frequency questionnaireMediterranean diet scoreBody mass indexCause of morbidity