2024
Dyadic care to improve postnatal outcomes of birthing people and their infants: A scoping review protocol
Choy C, McAdow M, Rosenberg J, Grimshaw A, Martinez-Brockman J. Dyadic care to improve postnatal outcomes of birthing people and their infants: A scoping review protocol. PLOS ONE 2024, 19: e0298927. PMID: 38625992, PMCID: PMC11020692, DOI: 10.1371/journal.pone.0298927.Peer-Reviewed Original ResearchConceptsCare interventionsBirthing personsHealth outcomesCare studiesJoanna Briggs Institute critical appraisal toolsPostnatal health outcomesReduce healthcare disparitiesImprove healthcare deliveryProvision of careCritical appraisal toolsWHO regional databasesRisk of biasOpen Science FrameworkObstetric careHealthcare disparitiesImplementation outcomesNarrative synthesisAppraisal ToolImprove disparitiesHealthcare deliveryGrey literaturePractice gapReview protocolWeb of Science Core CollectionHealthcare system
2022
Myometrial‐derived CXCL12 promotes lipopolysaccharide induced preterm labour by regulating macrophage migration, polarization and function in mice
Zhang L, Mamillapalli R, Habata S, McAdow M, Taylor HS. Myometrial‐derived CXCL12 promotes lipopolysaccharide induced preterm labour by regulating macrophage migration, polarization and function in mice. Journal Of Cellular And Molecular Medicine 2022, 26: 2566-2578. PMID: 35318804, PMCID: PMC9077289, DOI: 10.1111/jcmm.17252.Peer-Reviewed Original ResearchConceptsInflammation-related cytokinesSmooth muscle cellsPreterm laborCXCL12/CXCR4Preterm birthMacrophage migrationIL-6M1 polarizationPregnant miceImmune cellsCXCL12/CXCR4 axisTreatment of SMCsTumor necrosis factor alphaInduced preterm laborInfiltration of neutrophilsMacrophage M1 polarizationStart of labourNecrosis factor alphaTNF-α expressionPrimary smooth muscle cellsPremature laborPregnancy durationGestational tissuesMacrophage infiltrationNeonatal mortality
2020
Association of Oxytocin Rest During Labor Induction of Nulliparous Women With Mode of Delivery.
McAdow M, Xu X, Lipkind H, Reddy UM, Illuzzi JL. Association of Oxytocin Rest During Labor Induction of Nulliparous Women With Mode of Delivery. Obstetrics And Gynecology 2020, 135: 569-575. PMID: 32028487, DOI: 10.1097/aog.0000000000003709.Peer-Reviewed Original ResearchConceptsMode of deliveryInduction of laborNeonatal morbidityCesarean deliveryNulliparous womenLatent laborOxytocin infusionLatent phaseMultivariable logistic regression analysisContinuous oxytocin infusionRetrospective cohort analysisLarge academic medical centerBody mass indexLogistic regression analysisAcademic medical centerContinuous oxytocinSingleton gestationsLabor inductionGestational ageMass indexPotential confoundersMaternal ageOdds ratioCohort analysisMedical Center
2016
Antibodies against a secreted product of Staphylococcus aureus trigger phagocytic killing
Thomer L, Emolo C, Thammavongsa V, Kim H, McAdow M, Yu W, Kieffer M, Schneewind O, Missiakas D. Antibodies against a secreted product of Staphylococcus aureus trigger phagocytic killing. Journal Of Experimental Medicine 2016, 213: 293-301. PMID: 26880578, PMCID: PMC4813671, DOI: 10.1084/jem.20150074.Peer-Reviewed Original ResearchConceptsMethicillin-resistant Staphylococcus aureusBloodstream infectionsPhagocytic killingElicit cross-protective immune responsesCross-protective immune responsesProtective fibrin shieldS. aureus vaccineAureus vaccineClinical efficacyMRSA isolatesImmune cellsOpsonophagocytic killingFrequent causeImmune responseHost immunityHost prothrombinProtective antigenSpecific antibodiesInfectionSurface moleculesAntibodiesS. aureusStaphylococcus aureusAntibody therapeuticsStaphylococcal surface
2012
Coagulases as Determinants of Protective Immune Responses against Staphylococcus aureus
McAdow M, DeDent AC, Emolo C, Cheng AG, Kreiswirth BN, Missiakas DM, Schneewind O. Coagulases as Determinants of Protective Immune Responses against Staphylococcus aureus. Infection And Immunity 2012, 80: 3389-3398. PMID: 22825443, PMCID: PMC3457572, DOI: 10.1128/iai.00562-12.Peer-Reviewed Original Research
2010
IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge
Kim HK, DeDent A, Cheng AG, McAdow M, Bagnoli F, Missiakas DM, Schneewind O. IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge. Vaccine 2010, 28: 6382-6392. PMID: 20226248, PMCID: PMC3095377, DOI: 10.1016/j.vaccine.2010.02.097.Peer-Reviewed Original ResearchConceptsIntravenous challengeAbscess formationStaphylococcus aureus abscess formationLethal intravenous challengePathogenesis of infectionHospital-acquired infectionsStaphylococcal abscess formationNaïve miceActive immunizationLethal challengeSurface proteinsOpsonophagocytic killingStaphylococcal diseaseFrequent causeSubunit vaccineExperimental animalsMouse bloodAntibodiesStaphylococcus aureusBind hemoglobinVaccineInfectionMiceStaphylococciBacteremia