2019
Dissecting maternal care: Patterns of maternal parenting in a prospective cohort study
Unternaehrer E, Cost KT, Bouvette‐Turcot A, Gaudreau H, Massicotte R, Dhir SK, Dass S, O'Donnell KJ, Gordon‐Green C, Atkinson L, Levitan RD, Wazana A, Steiner M, Lydon JE, Clark R, Fleming AS, Meaney MJ, Team T. Dissecting maternal care: Patterns of maternal parenting in a prospective cohort study. Journal Of Neuroendocrinology 2019, 31: e12784. PMID: 31442354, DOI: 10.1111/jne.12784.Peer-Reviewed Original ResearchConceptsMaternal parentingParental brainChild outcomesMental healthMaternal parenting styleSelf-report measuresChild-reported symptomsAinsworth Sensitivity ScaleFactor analysisSelf-report questionnairesParenting variablesDifferent latent constructsSupportive parentingRelationship satisfactionAffectionate parentingMotivational componentParenting stylesExploratory factor analysisSchool readinessMultidimensional constructBehavioral problemsParentingBehavioral componentsCooperation taskMother-child bonding
2017
Maternal prenatal anxiety and child COMT genotype predict working memory and symptoms of ADHD
O'Donnell KJ, Glover V, Lahti J, Lahti M, Edgar RD, Räikkönen K, O'Connor TG. Maternal prenatal anxiety and child COMT genotype predict working memory and symptoms of ADHD. PLOS ONE 2017, 12: e0177506. PMID: 28614354, PMCID: PMC5470664, DOI: 10.1371/journal.pone.0177506.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxietyAttention Deficit Disorder with HyperactivityCatechol O-MethyltransferaseChildFemaleGene-Environment InteractionGenotypeHumansLongitudinal StudiesMaleMemory, Short-TermMothersPolymorphism, Single NucleotidePregnancyPrenatal Exposure Delayed EffectsProspective StudiesSelf ReportConceptsMaternal prenatal anxietySymptoms of ADHDPrenatal anxietyChildren's symptomsSelf-report measuresInter-individual differencesRs4680 genotypeIndividual differencesHyperactivity symptomsChildren's responsesADHDDevelopmental outcomesCOMT genotypeAnxietyAge 8 yearsMemoryVal/Val genotypeVal/ALSPAC cohortChild neurodevelopmentYears of ageFunctional genetic variationVal genotypeCOMTGene-environment interactionsMaternal prenatal cortisol predicts infant negative emotionality in a sex-dependent manner
Braithwaite EC, Pickles A, Sharp H, Glover V, O'Donnell KJ, Tibu F, Hill J. Maternal prenatal cortisol predicts infant negative emotionality in a sex-dependent manner. Physiology & Behavior 2017, 175: 31-36. PMID: 28322912, PMCID: PMC5429387, DOI: 10.1016/j.physbeh.2017.03.017.Peer-Reviewed Original ResearchConceptsNeonatal Behavioral Assessment ScaleSex-dependent mannerPrenatal stressMaternal prenatal cortisolPrenatal cortisolFemale infantInfant negative emotionalityFetal developmental trajectoriesMaternal saliva samplesProspective longitudinal cohortDevelopment Study cohortGeneral population estimatesBehavioral Assessment ScaleWirral Child HealthPrenatal cortisol levelsInverse probability weightsStudy cohortMale infantLongitudinal cohortFetal programmingChild healthEvening cortisolSex-specific developmental trajectoriesGlucocorticoid mechanismsPrevention strategies