2015
The Emerging Role of Angiogenic Factor Dysregulation in the Pathogenesis of Polycystic Ovarian Syndrome
Tal R, Seifer DB, Arici A. The Emerging Role of Angiogenic Factor Dysregulation in the Pathogenesis of Polycystic Ovarian Syndrome. Seminars In Reproductive Medicine 2015, 33: 195-207. PMID: 26036901, DOI: 10.1055/s-0035-1552582.Peer-Reviewed Original ResearchConceptsPolycystic ovarian syndromeGrowth factorOvarian syndromePathophysiology of PCOSAngiogenic factor imbalanceOvarian hyperstimulation syndromeCommon endocrine disorderVascular endothelial growth factorPlatelet-derived growth factorBasic fibroblast growth factorMultiple angiogenic factorsEndothelial growth factorFibroblast growth factorHyperstimulation syndromeOvulatory dysfunctionStromal vascularityAnovulatory infertilityPolycystic ovariesEndocrine disordersReproductive ageTreatment strategiesFollicular growthOvarian angiogenesisAngiogenic factorsCorpus luteum
2014
Is AMH a regulator of follicular atresia?
Seifer DB, Merhi Z. Is AMH a regulator of follicular atresia? Journal Of Assisted Reproduction And Genetics 2014, 31: 1403-1407. PMID: 25193290, PMCID: PMC4389943, DOI: 10.1007/s10815-014-0328-7.Peer-Reviewed Original ResearchConceptsFollicular atresiaNatural ovarian agingPolycystic ovary syndromeOnset of menopausePremature ovarian insufficiencyTreatment of PCOSDifferent patient populationsBasic science studiesTiming of onsetOvary syndromePatient populationOvarian agingOvarian failureHuman ovaryTreatment strategiesAMH productionOvarian insufficiencyIntraovarian regulatorsGrowth factorCellular originCritical growth factorsCancer therapyMenopauseAtresiaAMH