2025
United States racial/ethnic disparities in PGT-A use: an analysis of 2014–2020 SART CORS database
Mason-Otey A, Seifer D. United States racial/ethnic disparities in PGT-A use: an analysis of 2014–2020 SART CORS database. Reproductive Biology And Endocrinology 2025, 23: 66. PMID: 40349066, PMCID: PMC12065204, DOI: 10.1186/s12958-025-01399-8.Peer-Reviewed Original ResearchConceptsPGT-AMultiple logistic regressionART cyclesHispanic womenAsian womenSociety for Assisted Reproductive Technology Clinic Outcome Reporting SystemWhite womenSelection of euploid embryosPreimplantation genetic testingRetrospective cohort studyOutcome Reporting SystemAutologous ART cyclesSART CORS databaseEuploid embryosSART CORSAutologous cyclesCohort studyGenetic testingMinority womenLogistic regressionWomenBackgroundThe useResultsThis studyUnited StatesRacial/ethnic disparities
2024
UNITED STATES RACIAL/ETHNIC DISPARITIES IN OUTCOMES USING PGT-A: AN ANALYSIS OF 2014-2020 SART CORS DATABASE
Mason-Otey A, Seifer D. UNITED STATES RACIAL/ETHNIC DISPARITIES IN OUTCOMES USING PGT-A: AN ANALYSIS OF 2014-2020 SART CORS DATABASE. Fertility And Sterility 2024, 122: e381. DOI: 10.1016/j.fertnstert.2024.08.171.Peer-Reviewed Original ResearchAssessment of a Decade of Change in U.S. Assisted Reproductive Technology Cumulative Live-Birth Rates
Wang S, Seifer D. Assessment of a Decade of Change in U.S. Assisted Reproductive Technology Cumulative Live-Birth Rates. Obstetrics And Gynecology 2024, 143: 839-848. PMID: 38696814, DOI: 10.1097/aog.0000000000005598.Peer-Reviewed Original ResearchConceptsCumulative live birth rateLive birth rateAssisted reproductive technologyPreimplantation genetic testingInfertility diagnosisLive birthsOvulatory disordersGenetic testingReproductive technologyOdds of live birthMale factor infertilityFrozen embryo transferDiminished ovarian reserveClinical practiceRetrospective cohort studyAssociated with decreased oddsSART CORS databaseField of assisted reproductive technologyDemographic shiftsSART CORSOvarian reserveInfertility causeEmbryo transferCounseling patientsCohort study
2023
Cumulative live birth rates with autologous oocytes plateau with fewer number of cycles for each year of age > 42
Seifer D, Wang S, Frankfurter D. Cumulative live birth rates with autologous oocytes plateau with fewer number of cycles for each year of age > 42. Reproductive Biology And Endocrinology 2023, 21: 94. PMID: 37872609, PMCID: PMC10591412, DOI: 10.1186/s12958-023-01144-z.Peer-Reviewed Original ResearchConceptsCumulative live birth rateLive birth rateART cyclesBirth rateDesignRetrospective cohort studyPrior ART cyclesUse of ICSIEtiology of infertilityNumber of oocytesAge categoriesSART CORS databaseYears of ageTreatment cycle numberRace/ethnicityAutologous cyclesResultsBetween 2014Ovarian reserveCohort studyBlastocyst transferWomen 46Women 42Age 45Live birthsMAIN OUTCOMEPhysician expectationsAMH predicts miscarriage in non-PCOS but not in PCOS related infertility ART cycles
Arkfeld C, Han E, Tal R, Seifer D. AMH predicts miscarriage in non-PCOS but not in PCOS related infertility ART cycles. Reproductive Biology And Endocrinology 2023, 21: 35. PMID: 37020210, PMCID: PMC10074664, DOI: 10.1186/s12958-023-01087-5.Peer-Reviewed Original ResearchConceptsBody mass indexMiscarriage rateMean AMHART cyclesNumber of embryosElevated AMHAMH valuesOdds ratioNon-PCOS patientsOverall miscarriage rateConfidence intervalsAutologous embryo transferSART CORS databaseMultivariate regression analysisHeterotopic pregnancyClinical pregnancyAMH levelsIVF cyclesPCOS patientsPCOS populationIndependent predictorsMass indexPatient populationOocyte bankingAutologous transferAMH independently predicts aneuploidy but not live birth per transfer in IVF PGT-A cycles
Li H, Seifer D, Tal R. AMH independently predicts aneuploidy but not live birth per transfer in IVF PGT-A cycles. Reproductive Biology And Endocrinology 2023, 21: 19. PMID: 36739415, PMCID: PMC9898926, DOI: 10.1186/s12958-023-01066-w.Peer-Reviewed Original ResearchConceptsAnti-Müllerian hormoneNumber of embryosEuploid embryosLive birthsOocyte qualityAge groupsSignificant independent predictorsCase-control analysisSART CORS databasePreimplantation genetic testingAMH levelsIVF cyclesIndependent predictorsIVF outcomesOocyte yieldNormal embryosPredictive roleGenetic testingFinal analysisBirthAgeIVFSubset of cyclesHormonePGT
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