2023
AMH predicts miscarriage in non-PCOS but not in PCOS related infertility ART cycles
Arkfeld C, Han E, Tal R, Seifer D. AMH predicts miscarriage in non-PCOS but not in PCOS related infertility ART cycles. Reproductive Biology And Endocrinology 2023, 21: 35. PMID: 37020210, PMCID: PMC10074664, DOI: 10.1186/s12958-023-01087-5.Peer-Reviewed Original ResearchConceptsBody mass indexMiscarriage rateMean AMHART cyclesNumber of embryosElevated AMHAMH valuesOdds ratioNon-PCOS patientsOverall miscarriage rateConfidence intervalsAutologous embryo transferSART CORS databaseMultivariate regression analysisHeterotopic pregnancyClinical pregnancyAMH levelsIVF cyclesPCOS patientsPCOS populationIndependent predictorsMass indexPatient populationOocyte bankingAutologous transfer
2020
OVERCOMPENSATING? THE USE OF ICSI FOR NON-MALE FACTOR INFERTILITY DOES NOT IMPROVE LIVE BIRTH RATE IN A MATCHED PATIENT POPULATION
Glenn T, Kelk D, Wininger M, Seifer D. OVERCOMPENSATING? THE USE OF ICSI FOR NON-MALE FACTOR INFERTILITY DOES NOT IMPROVE LIVE BIRTH RATE IN A MATCHED PATIENT POPULATION. Fertility And Sterility 2020, 114: e299-e300. DOI: 10.1016/j.fertnstert.2020.08.820.Peer-Reviewed Original Research
2016
Biosimilar FSH preparations- are they identical twins or just siblings?
Orvieto R, Seifer DB. Biosimilar FSH preparations- are they identical twins or just siblings? Reproductive Biology And Endocrinology 2016, 14: 32. PMID: 27301324, PMCID: PMC4908720, DOI: 10.1186/s12958-016-0167-8.Peer-Reviewed Original ResearchConceptsFSH preparationsPregnancy rateClinical practicePhase 3 clinical trialsIncidence of OHSSOngoing pregnancy ratePolycystic ovary syndromeAdditional patient populationsPopulation of womenDose-response curveRecombinant FSH preparationsBiosimilar productsNormal respondersIVF failurePoor respondersOvary syndromeClinical efficacyPatient populationClinical trialsBiosimilar agentsSteelman-PohleyClinical useFurther comparative studiesPatientsIdentical twins
2014
Is AMH a regulator of follicular atresia?
Seifer DB, Merhi Z. Is AMH a regulator of follicular atresia? Journal Of Assisted Reproduction And Genetics 2014, 31: 1403-1407. PMID: 25193290, PMCID: PMC4389943, DOI: 10.1007/s10815-014-0328-7.Peer-Reviewed Original ResearchConceptsFollicular atresiaNatural ovarian agingPolycystic ovary syndromeOnset of menopausePremature ovarian insufficiencyTreatment of PCOSDifferent patient populationsBasic science studiesTiming of onsetOvary syndromePatient populationOvarian agingOvarian failureHuman ovaryTreatment strategiesAMH productionOvarian insufficiencyIntraovarian regulatorsGrowth factorCellular originCritical growth factorsCancer therapyMenopauseAtresiaAMH
2012
High frequency of discordance between antimüllerian hormone and follicle-stimulating hormone levels in serum from estradiol-confirmed days 2 to 4 of the menstrual cycle from 5,354 women in U.S. fertility centers
Leader B, Hegde A, Baca Q, Stone K, Lannon B, Seifer DB, Broekmans F, Baker VL. High frequency of discordance between antimüllerian hormone and follicle-stimulating hormone levels in serum from estradiol-confirmed days 2 to 4 of the menstrual cycle from 5,354 women in U.S. fertility centers. Fertility And Sterility 2012, 98: 1037-1042. PMID: 22771028, DOI: 10.1016/j.fertnstert.2012.06.006.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAnti-Mullerian HormoneChemistry, ClinicalEstradiolFemaleFertilityFollicle Stimulating Hormone, HumanHumansMenstrual CycleMiddle AgedOocytesOvulation InductionPredictive Value of TestsPrognosisReference StandardsReproductive MedicineRetrospective StudiesUnited StatesYoung AdultConceptsYears of ageFSH valuesSerum AMHAntimüllerian hormoneAMH valuesFertility centerCut pointsDay 2Clinical discordanceMenstrual cycle day 2Follicle-stimulating hormone levelsCycle day 2Reference laboratoryFollicle-stimulating hormoneLarger patient populationSingle reference laboratoryFrequency of discordanceAge-dependent fashionClinical cut pointsSame serum samplesOvarian stimulationPatient populationAMH testingMenstrual cycleHormone levels