Medical therapy to treat obesity and optimize fertility in women of reproductive age: a narrative review
Duah J, Seifer D. Medical therapy to treat obesity and optimize fertility in women of reproductive age: a narrative review. Reproductive Biology And Endocrinology 2025, 23: 2. PMID: 39762910, PMCID: PMC11702155, DOI: 10.1186/s12958-024-01339-y.Peer-Reviewed Original ResearchConceptsWomen of reproductive ageFDA-approved medicationsGLP1-RAsReproductive ageTotal body weightWeight lossBariatric surgeryPreconception periodBody fat promotes adipose tissue dysfunctionResponse to ovulation inductionCombination of phentermineFirst-line therapyAdvanced maternal ageLive birth rateGLP1 receptor agonistsWeight loss medicationsPoor oocyte qualityRisk of surgeryCombination of naltrexoneSignificant side effectsMetabolic health factorsBody weightSignificant weight lossAnti-obesity drugsNovel pharmacological agents
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