2025
Medical therapy to treat obesity and optimize fertility in women of reproductive age: a narrative review
Duah J, Seifer D. Medical therapy to treat obesity and optimize fertility in women of reproductive age: a narrative review. Reproductive Biology And Endocrinology 2025, 23: 2. PMID: 39762910, PMCID: PMC11702155, DOI: 10.1186/s12958-024-01339-y.Peer-Reviewed Original ResearchConceptsWomen of reproductive ageFDA-approved medicationsGLP1-RAsReproductive ageTotal body weightWeight lossBariatric surgeryPreconception periodBody fat promotes adipose tissue dysfunctionResponse to ovulation inductionCombination of phentermineFirst-line therapyAdvanced maternal ageLive birth rateGLP1 receptor agonistsWeight loss medicationsPoor oocyte qualityRisk of surgeryCombination of naltrexoneSignificant side effectsMetabolic health factorsBody weightSignificant weight lossAnti-obesity drugsNovel pharmacological agents
1986
A critical reassessment of second‐look laparotomy in epithelial ovarian carcinoma
Miller D, Ballon S, Teng N, Seifer D, Soriero O. A critical reassessment of second‐look laparotomy in epithelial ovarian carcinoma. Cancer 1986, 57: 530-535. PMID: 3942985, DOI: 10.1002/1097-0142(19860201)57:3<530::aid-cncr2820570321>3.0.co;2-5.Peer-Reviewed Original ResearchConceptsSecond-look laparotomyEpithelial ovarian carcinomaOvarian carcinomaPersistent tumorSecond-line salvage therapyMultivariate logistic regression analysisPersistent ovarian carcinomaComplete clinical responseComplete pathologic responseFirst-line chemotherapyFirst-line therapyEvidence of recurrenceLarge residual tumorRisk of recurrenceLogistic regression analysisDisease-free statusCurative intentSalvage therapyAdjunctive therapyClinical responsePathologic evidencePathologic responseMicroscopic diseaseResidual tumorGross tumor
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