2022
State insurance mandates for in vitro fertilization are not associated with improving racial and ethnic disparities in utilization and treatment outcomes
Correia K, Kraschel K, Seifer D. State insurance mandates for in vitro fertilization are not associated with improving racial and ethnic disparities in utilization and treatment outcomes. American Journal Of Obstetrics And Gynecology 2022, 228: 313.e1-313.e8. PMID: 36356698, DOI: 10.1016/j.ajog.2022.10.043.Peer-Reviewed Original ResearchConceptsNon-Hispanic white womenClinical outcomesEthnic disparitiesFertilization cyclesFertility careAssisted Reproductive Technology Clinical Outcomes Reporting SystemBlack/African American womenWhite womenSingle stimulation cycleInsurance mandatesReproductive-aged womenRecent study yearsLack of insuranceAfrican American womenAutologous cyclesLiveborn neonatesCohort studyPrimary outcomeState insurance mandatesState health insurance mandatesStimulation cyclesTreatment outcomesWomenHealth insurance mandatesOutcomes
2020
Anti-Müllerian hormone as a qualitative marker - or just quantity?
Kotlyar A, Seifer DB. Anti-Müllerian hormone as a qualitative marker - or just quantity? Current Opinion In Obstetrics & Gynecology 2020, 32: 219-226. PMID: 32205525, DOI: 10.1097/gco.0000000000000623.Peer-Reviewed Original ResearchConceptsAnti-Müllerian hormoneOvarian reserve testingClinical pregnancy rateLive birth rateOnset of menopausePremature ovarian insufficiencyNumber of oocytesSignificant predictive valueAMH levelsFertilization cyclesPregnancy rateOvarian insufficiencyIntracycle variabilityOocyte qualityPredictive valueEarly folliclesFetal trisomiesHormoneReproductive technologiesRiskQualitative markersSmall interMenopauseInsufficiencyFollicles
2018
Risk of severe maternal morbidity by maternal fertility status: a US study in 8 states
Luke B, Brown MB, Wantman E, Baker VL, Doody KJ, Seifer DB, Spector LG. Risk of severe maternal morbidity by maternal fertility status: a US study in 8 states. American Journal Of Obstetrics And Gynecology 2018, 220: 195.e1-195.e12. PMID: 30321527, PMCID: PMC9758649, DOI: 10.1016/j.ajog.2018.10.012.Peer-Reviewed Original ResearchConceptsSevere maternal morbidityMaternal fertility statusMaternal morbidityFertile womenBirth certificatesFertilization pregnanciesCesarean deliveryBlood transfusionInfertility treatmentUnplanned hysterectomyOocyte sourceFourth-degree perineal lacerationsOlder maternal ageInfant birth certificatesCharacteristics of womenSample of birthsSubfertile womenFertilization cyclesFresh cyclesPerineal lacerationsVaginal birthMaternal ageOdds ratioLive birthsStudy populationTemporal Differences in Utilization of Intracytoplasmic Sperm Injection Among U.S. Regions
Zagadailov P, Hsu A, Stern JE, Seifer DB. Temporal Differences in Utilization of Intracytoplasmic Sperm Injection Among U.S. Regions. Obstetrics And Gynecology 2018, 132: 310-320. PMID: 29995722, DOI: 10.1097/aog.0000000000002730.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCohort StudiesFemaleFertilization in VitroHumansInfertility, FemaleInfertility, MaleLive BirthMalePregnancyPregnancy RateRetrospective StudiesSperm Injections, IntracytoplasmicTreatment OutcomeUnited StatesUnited States Dept. of Health and Human ServicesYoung AdultConceptsLive birth rateUse of ICSIICSI rateICSI utilizationBirth rateRetrospective cohort studyMale factor infertilityHuman Services (HHS) regionsIntracytoplasmic sperm injectionYears of agePreimplantation genetic testingMale factor diagnosisDepartment of HealthNondonor cyclesCohort studyFertilization cyclesFactor infertilityMale factorSperm injectionMedical indicationsMagnitude of increaseClinicGenetic testingDisease controlICSI
2014
Successful Same-Cycle Blastocyst Transfer following Laparoscopic Ovarian Detorsion: A Report of Two Cases and Literature Review
Irani M, Tal R, Seifer DB, Grazi RV. Successful Same-Cycle Blastocyst Transfer following Laparoscopic Ovarian Detorsion: A Report of Two Cases and Literature Review. Case Reports In Obstetrics And Gynecology 2014, 2014: 806378. PMID: 24864219, PMCID: PMC4020476, DOI: 10.1155/2014/806378.Peer-Reviewed Original ResearchOvarian torsionEmbryo transferOocyte retrievalFavorable pregnancy outcomeLaparoscopic ovarian detorsionOvarian detorsionLaparoscopic evaluationOvarian stimulationPregnancy outcomesFertilization cyclesInfertility patientsPregnancy chancesSuccessful pregnancyBlastocyst transferEgg retrievalClinical dilemmaOptimal timingDetorsionPatientsConcurrent cyclesSuch casesLiterature reviewPregnancyIVFCases
2000
Inhibin B response to EFORT is associated with the outcome of oocyte retrieval in the subsequent in vitro fertilization cycle
Dzik A, Lambert-Messerlian G, Izzo V, Soares J, Pinotti J, Seifer D. Inhibin B response to EFORT is associated with the outcome of oocyte retrieval in the subsequent in vitro fertilization cycle. Fertility And Sterility 2000, 74: 1114-1117. PMID: 11119736, DOI: 10.1016/s0015-0282(00)01627-7.Peer-Reviewed Original ResearchConceptsInhibin B levelsInhibin B serum levelsB levelsInhibin B responsesSubsequent IVF cycleLevels 24 hoursAcademic clinical practiceGood responsePg/mLGonadotropin challengeBaseline serumInhibin BIVF cyclesOvarian stimulationOocyte retrievalOvarian reserveFertilization cyclesOvarian responseSerum levelsPoor responseOdds ratioMAIN OUTCOMEClinical practiceCorresponding oddsPg/
1998
Predicting Probabilities of Pregnancy and Multiple Gestation From In Vitro Fertilization—A New Model
WHEELER C, COLE B, FRISHMAN G, SEIFER D, LOVEGREEN S, HACKETT R. Predicting Probabilities of Pregnancy and Multiple Gestation From In Vitro Fertilization—A New Model. Obstetrics And Gynecology 1998, 91: 696-700. DOI: 10.1097/00006250-199805000-00010.Peer-Reviewed Original ResearchConceptsMultiple gestationsProbability of pregnancyEmbryo scoreNumber of embryosThird implantationFertilization cyclesInfant HospitalIVF programVitro FertilizationEmbryo transferPregnancySecond implantationLogistic regressionPatient-specific informationGestationP2/P1Embryo scoringHospitalScoresAgeImplantationBest predictorP3/P2Patients
1994
Early and late presentation of the ovarian hyperstimulation syndrome: two distinct entities with different risk factors*
Lyons CA, Wheeler CA, Frishman GN, Hackett RJ, Seifer DB, Haning RV. Early and late presentation of the ovarian hyperstimulation syndrome: two distinct entities with different risk factors*. Human Reproduction 1994, 9: 792-799. PMID: 7929724, DOI: 10.1093/oxfordjournals.humrep.a138598.Peer-Reviewed Original ResearchConceptsLate ovarian hyperstimulation syndromeOvarian hyperstimulation syndromeSevere ovarian hyperstimulation syndromeNumber of oocytesHyperstimulation syndromeEarly ovarian hyperstimulation syndromePost-human chorionic gonadotrophinDifferent risk factorsStepwise logistic regressionSeries of casesDay-hCGMultiple gestationsClinical predictorsFertilization cyclesGestational sacEarly pregnancyLate presentationOestradiol concentrationsSerum concentrationsEgg retrievalRisk factorsHigh oestradiolAcute effectsChorionic gonadotrophinRetrospective analysisDehydroepiandrosterone sulfate and anovulation increase serum inhibin and affect follicular function during administration of gonadotropins
Haning RV, Hua JJ, Hackett RJ, Wheeler CA, Frishman GN, Seifer DB, Dahl CA, Burger HG. Dehydroepiandrosterone sulfate and anovulation increase serum inhibin and affect follicular function during administration of gonadotropins. The Journal Of Clinical Endocrinology & Metabolism 1994, 78: 145-149. PMID: 8288697, DOI: 10.1210/jcem.78.1.8288697.Peer-Reviewed Original ResearchConceptsNumber of oocytesAnovulatory subjectsSerum inhibinAnovulatory ovariesSerum concentrationsNormal subjectsSerum DS concentrationSerum inhibin concentrationsAdministration of gonadotropinSecretion of inhibinResidual serum samplesDuration of treatmentAnovulatory patientsGonadotropin therapyInhibin concentrationsInhibin secretionPatient ageFertilization cyclesGonadotropin treatmentLH dosesFollicular functionHCG treatmentInhibinAverage durationSerum samples
1992
Luteinizing response to human chorionic gonadotropin does not predict outcome in gonadotropin releasing hormone agonist-suppressed/human menopausal gonadotropin-stimulated in vitro fertilization (IVF) cycles
Penzias A, Shamma F, Gutmann J, Seifer D, DeCherney A, Lavy G. Luteinizing response to human chorionic gonadotropin does not predict outcome in gonadotropin releasing hormone agonist-suppressed/human menopausal gonadotropin-stimulated in vitro fertilization (IVF) cycles. Journal Of Assisted Reproduction And Genetics 1992, 9: 244-247. PMID: 1525454, DOI: 10.1007/bf01203821.Peer-Reviewed Original Research