Shattered Conception Podcast: Episode 39. The Placenta and What It Tells Us with Harvey Kliman, M.D., Ph.D.
My guest on Episode 39 of Shattered Conception is Dr. Harvey Kliman who has, in addition to an M.D., holds a Ph.D. in cellular biochemistry from the University of Chicago. He is currently a Research Scientist in the Department of Obstetrics and Gynecology at Yale University School of Medicine and the Director of the Reproductive and Placental Research Unit with a special interest in infertility, pregnancy complications, pregnancy loss(es) and stillbirth.Source: Shattered Conception
Hope for women with recurring pregnancy losses
For some, every pregnancy ends in a loss within six weeks. “These particular patients always have losses and they are not infertile. They get pregnant easily but they always have these losses,” says Dr. Harvey Kliman, director of the Reproductive and Placental Research Unit in the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale School of Medicine.Source: WTNH
Progesterone may be key to preventing recurrent miscarriage
For women who suffer multiple pregnancy losses in the first four to six weeks of gestation, the hormone progesterone could offer hope for a successful birth, according to a new study by Yale School of Medicine researchers and their colleagues at University of Illinois at Chicago.
Autism Treatment For Under-Threes Is Key, But Diagnosis Is Tough
Most children with autism are well past their fourth birthday by the time they're diagnosed with the condition, according to new government data. Their parents and teachers may have raised red flags earlier, but it takes months or years to confirm suspicions with a formal diagnosis. And therapy rarely starts without one. "The school wouldn't do anything for us until we had a diagnosis," said Kimberly Vincent, of Wallingford, whose daughter Rebekah was diagnosed at age 6.Source: The Hartford Courant
Early Childhood Autism Treatment Is Key, But Diagnosis Is Difficult
Most children with autism are well past their fourth birthday by the time they’re diagnosed with the condition, according to new government data. Although the average age of diagnosis is nearly four-and-a-half, diagnoses can reliably be made around age two. Their parents and teachers may have raised red flags earlier, but it takes months or years to confirm suspicions with a formal diagnosis. And therapy rarely starts without one.Source: WNPR
Experts: Autism treatment for kids under 3 is key, but diagnosis tough
Most children with autism are well past their fourth birthday by the time they’re diagnosed with the condition, according to new government data. Their parents and teachers may have raised red flags earlier, but it takes months or years to confirm suspicions with a formal diagnosis. And therapy rarely starts without one.Source: New Haven Register
Genetic anomalies account for majority of miscarriages
A substantial majority of miscarriages appear to be caused by genetic abnormalities rather than the usual suspects of thrombophilias, antiphospholipid syndromes, immunologic problems, or other maternal factors, study results suggest.Source: Ob.Gyn. News
New York Times: Study Ties Autism Risk to Creases in Placenta
After most pregnancies, the placenta is thrown out, having done its job of nourishing and supporting the developing baby. But a new study raises the possibility that analyzing the placenta after birth may provide clues to a child’s risk for developing autism.Source: The New York Times
Abnormal placenta may reveal newborn’s autism risk
A new study published in the online issue of Biological Psychiatry, senior author Dr. Harvey Kliman and his colleagues examined abnormal placental folds and cell growths called trophoblast inclusions, which acted as effective biomarkers for predicting which children were at risk for developing ASD.Source: FOX NEWS
Placentas provide clues about autism risk at birth, study says
Researchers believe they have come up with a way to tell whether a newborn infant has a higher-than-normal risk of developing autism -- by looking for abnormalities in the placenta shortly after birth. The abnormalities in question are called trophoblast inclusions, or TIs.Source: Los Angeles Times
Autism May Be Linked to Placenta Abnormalities
It's much too early to say that an examination of the placenta could be used as a definitive test for autism at birth, said study researcher Dr. Harvey Kliman, director of Reproductive and Placental Research at the Yale University School of Medicine. Autism spectrum disorders are typically diagnosed when children are ages 3 or 4, or even older.Source: MyHeatlhNewsDaily
Autism risk spotted at birth in abnormal placentas
Researchers at the Yale School of Medicine have figured out how to measure an infant’s risk of developing autism by looking for abnormalities in his/her placenta at birth, allowing for earlier diagnosis and treatment for the developmental disorder. The findings are reported in the April 25 online issue of Biological Psychiatry.
Turncoat of Placenta Is Watched for Trouble
In mother-and-child paintings and Henry Moore sculptures, mothers and babies meld together with such ease they appear as one. But in the course of some pregnancies, the embryo’s struggle for nutrients can escalate into all-out war with the mother, a dangerous condition called pre-eclampsia.Source: New York Times
Battle between the placenta and uterus could help explain preeclampsia
A battle that brews in the mother’s womb between the father’s biological goal to produce the biggest, healthiest baby possible vs. the mother’s need to live through delivery might help explain preeclampsia, an often deadly disease of pregnancy. The fetus must be big enough to thrive, yet small enough to pass through the birth canal. In a new study, Yale researchers describe the mechanism that keeps these conflicting goals in balance.