Shattered Conception Podcast: Episode 39. The Placenta and What It Tells Us with Harvey Kliman, M.D., Ph.D.
My guest on Episode 39 of Shattered Conception is Dr. Harvey Kliman who has, in addition to an M.D., holds a Ph.D. in cellular biochemistry from the University of Chicago. He is currently a Research Scientist in the Department of Obstetrics and Gynecology at Yale University School of Medicine and the Director of the Reproductive and Placental Research Unit with a special interest in infertility, pregnancy complications, pregnancy loss(es) and stillbirth.Source: Shattered Conception
Autism risk spotted at birth in abnormal placentas
Researchers at the Yale School of Medicine have figured out how to measure an infant’s risk of developing autism by looking for abnormalities in his/her placenta at birth, allowing for earlier diagnosis and treatment for the developmental disorder. The findings are reported in the April 25 online issue of Biological Psychiatry.
Digital Self‑harm is Associated With Disordered Eating Behaviors in Adults
Janet Lydecker, PhD, assistant professor of psychiatry, and colleagues studied the new phenomenon of “digital self-harm” and found that it was associated with disordered eating. Digital self-harm is when people post mean things about themselves (anonymously) online, so it appears they have been cyberbullied. The study results were published in Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity.Source: Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity
Survey of Americans Who Attempted Suicide Finds Many Aren’t Getting Care
The number of people who try suicide has risen steadily in the United States. But despite gains in health coverage, nearly half are not getting mental health treatment, according to a new Yale study published in JAMA Psychiatry.Source: The New York Times
Transient Neuronal Suppression for Exploitation of New Sensory Evidence
In noisy but stationary environments, decisions should be based on the temporal integration of sequentially sampled evidence, but it remains poorly understood how decisions should be made in the face of dynamically changing sensory evidence. According to a new study published in Nature Communications, abrupt change in evidence leads to a brief suppression of behavioral response, which parallels a corresponding dip in neural activity. Yale Department of Psychiatry scientists Hyojung Seo, PhD, and John D. Murray, PhD, are co-authors.Source: Nature Communications
Hippocampal Acetylcholine Modulates Stress-Related Behaviors Independent of Speciﬁc Cholinergic Inputs
Yann Mineur, PhD, MS, research scientist in psychiatry, and Marina Picciotto, PhD, Charles B. G. Murphy Professor of Psychiatry and Professor in the Child Study Center, of Neuroscience and of Pharmacology, are first and senior authors, respectively of a paper in Molecular Psychiatry that studied acetylcholine release in the hippocampus in response to stress.Source: Molecular Psychiatry
Cannabis and Psychosis: Recent Epidemiological Findings Continuing the “Causality Debate”
In a new piece published in The American Journal of Psychiatry, Suhas Ganeesh, MD, postdoctoral associate in psychiatry, and Deepak Cyril D'Souza, MD, professor of psychiatry at Yale School of Medicine, argue that if cannabis caused psychosis, then the increases in the rates of cannabis use should be accompanied by a parallel increase in the rates of psychosis.Source: The American Journal of Psychiatry
New‐Onset and Exacerbated Insomnia Symptoms During the COVID‐19 Pandemic in US Military Veterans
Jason DeViva, PhD; Peter Na, MD, MPH; and Robert Pietrzak, PhD, MPH are co-authors of a study in Journal of Sleep Research that evaluated pre- and pandemic-related factors associated with new-onset and exacerbated insomnia symptoms in a nationally representative sample of 3,078 United States military veteransSource: Journal of Sleep Research
COVID-19 and PTSD: Assessing the Pandemic’s Toll on Mental Health
As researchers and clinicians continue to grapple with the psychological fallout from COVID-19, a growing body of literature has examined the prevalence of post-traumatic stress disorder (PTSD) in the general public. Women’s Health Research at Yale and its collaborators published a study questioning how these estimates vary so greatly and if such wide swaths of the public can truly be suffering from pandemic-related PTSD.
What West Point Graduates Can Teach Us About Stress and Resilience
To explore how to promote psychological resilience and prevent negative health outcomes among such individuals, Dr. Melissa Thomas investigated the long-term physical and mental health risks and resilience of her fellow graduates from the U.S. Military Academy at West Point. It was the first study to focus on graduates and consider gender differences in these topic areas since the elite institution’s integration of women in 1980.
Nasal Vaccination May Protect Against Respiratory Viruses Better Than Injected Vaccines
Akiko Iwasaki, PhD, discusses her lab's finding that intranasal vaccinations, by triggering immune properties of mucosal membranes, may offer better protection against respiratory viruses than injected vaccines.
Nasal Vaccine May Aid Fight Against New Viral Variants
Akiko Iwasaki and her colleagues found that intranasal vaccination provided broad-based protection against heterologous respiratory viruses in mice, while so-called systemic immunization, which uses an injection to elicit body-wide protection, did not.Source: YaleNews