Colton Center Request for Proposals
Colton Center for Autoimmunity at Yale is requesting project proposals to advance innovative translational research in autoimmune and allergic diseases, including but not limited to, discovery and development of therapeutics; identification and validation of therapeutic targets; development of drug delivery system and other platform technologies; as well as development of diagnostics, or biomarkers for patient stratification during clinical trials.
Yale scientists chosen by White House to expedite cancer research
Yale is one of three institutions that have been honored with the White House Cancer Moonshot research grant. Yale's Douglas Hanlon, PhD, research scientist in dermatology, and Richard Edelson, MD, the Anthony N. Brady Professor of Dermatology, describe their groundbreaking research, using mRNA technology to create a vaccine that targets only cancer cells.Source: WTNH News 8
Discovering the 'Cytokine Language' That Activates Immune Responses
Using a new computational method based on a causal inference framework, CINEMA-OT, the Yale team studied how individual immune cells react to combinations of cytokines, or small proteins released by cells that regulate inflammation. They discovered that certain cytokines have a synergistic effect, inducing unique gene activation programs compared to their individual effects. This cryptography of cytokine signals acts as a language, instructing immune cells.
Immune Sensing of Allergens Promotes Avoidance Behavior
A new study published in Nature demonstrates how the immune system plays a role in the development of behaviors to avoid food allergens. Previous research has suggested that the immune system may be involved in behavioral modification beyond simply protecting the body from infectious diseases.
Introducing the Internal Medicine 2021-2022 Annual Report
In the new report, there are updates from our clinical programs, research endeavors, our work on diversity, equity, and inclusion, and educational programs. Our faculty members were honored for their educational excellence. Research initiatives at Yale received applause on the national and international stages. This book highlights all that we have accomplished together this past year…
YSM Faculty Developing “Game Changer” for Global Health
Dengue. Zika. Lyme. Yellow fever. Chikungunya virus. Malaria. These worldwide diseases, and others, are spread by the bite from an infected arthropod, a tick or mosquito. Five faculty from Yale School of Medicine (YSM) are collaborating on a project focusing on creating vaccines against infectious diseases by targeting the vector, which could be a “game changer” for global health.
‘Prime and Spike’ Nasal Vaccine Strategy Helps Combat COVID
The new “prime” and “spike” approach may help prevent breakthrough infections of vaccinated individuals by bolstering immune response within the mucosal lining of the respiratory tract, which are the first cells attacked by COVID-19.Source: YaleNews
Marie Robert, MD, Jordan Pober, MD, PhD, Awarded POINTS Grant to Study Pathogenesis of Celiac Disease
Marie Robert, MD, Professor of Pathology and of Medicine (Digestive Diseases), and Jordan Pober, MD, PhD, the Bayer Professor of Translational Medicine and Professor of Immunobiology, Pathology, and Dermatology, have been awarded a grant from the Program for the Promotion of Interdisciplinary Team Science (POINTS) at Yale School of Medicine to study the Pathogenesis of Celiac Disease.
Calorie Reduction Lowers Protein Linked to the Aging Process
In a new study, Yale researchers show that moderate calorie restriction in people reduces the production of a protein called SPARC, which then reins in harmful inflammation and improves health in the aged. It could be a target for extending human health span, they report.
Irina Krykbaeva, PhD, Awarded 2022 Milton C. Winternitz Prize in Pathology
Irina Krykbaeva, a recent PhD graduate in the Department of Pathology at Yale School of Medicine, is the winner of the 2022 Milton C. Winternitz Prize in Pathology. The prize is awarded annually to the student who, in the opinion of the department faculty and staff, has done outstanding work in the course.
Vishwa Deep Dixit, DVM, PhD, Appointed Director of the Yale Center for Research on Aging (Y-Age) and Professor of Pathology at Yale Pathology
Vishwa Deep Dixit, DVM, PhD, the Waldemar Von Zedtwitz Professor of Comparative Medicine and Immunobiology at Yale School of Medicine, will be appointed as Director of the Yale Center for Research on Aging (Y-Age) and Professor of Pathology on January 1, 2022.
Ask tough questions: PhD student Sebastian Diaz
Sebastian Diaz, a PhD student in immunobiology at Yale School of Medicine (YSM), said it’s hard to be among the pioneers, but because medical students from underrepresented backgrounds have pushed for greater emphasis on diversity, equity, and inclusion (DEI) supported by resources “We have a very robust system that is now becoming bigger and bigger every year.”
Common Cold Could Protect Against COVID In Early Stages Of Infection
t’s hard to envision the common cold, caused by rhinoviruses, as something of a superhero, but recent research from Yale University has found this bug to have an intriguing effect on the early success of the pathogen that causes COVID-19 in the body.Source: IFLScience