2022
Noninvasive amino acid turnover predicts human embryo aneuploidy
Olcay IO, Akcay B, Bahceci M, Arici A, Boynukalin K, Yakicier C, Ozpinar A, Basar M. Noninvasive amino acid turnover predicts human embryo aneuploidy. Gynecological Endocrinology 2022, 38: 461-466. PMID: 35481385, DOI: 10.1080/09513590.2022.2068520.Peer-Reviewed Original ResearchConceptsEuploid groupAneuploid groupAmino acid turnoverAneuploid embryosHigher implantation rateAmino acid metabolism profilePotential diagnostic testPreimplantation genetic testingAcid turnoverBlank control groupEmbryo selection criteriaAssisted reproduction technologyMultiple pregnanciesImplantation ratePatient groupAmino acid concentrationsAneuploid blastocystsEmbryo aneuploidyControl groupDay 5IVF clinicsLow success rateGenetic testingCulture mediumTE biopsy
2014
The comparative effects of perindopril and catechin on mesangial matrix and podocytes in the streptozotocin induced diabetic rats
Ertürküner S, Başar M, Tunçdemir M, Seçkin İ. The comparative effects of perindopril and catechin on mesangial matrix and podocytes in the streptozotocin induced diabetic rats. Pharmacological Reports 2014, 66: 279-287. PMID: 24911082, DOI: 10.1016/j.pharep.2013.09.010.Peer-Reviewed Original ResearchConceptsUntreated diabetic groupDiabetic groupMesangial matrixControl groupDiabetic nephropathyDiabetes mellitusEnd-stage kidney failureOxidative stressExperimental diabetic nephropathyHigh blood pressureAdult Wistar AlbinoGlomerular mesangial matrixBlood glucose valuesExcessive reactive oxygen species (ROS) productionReactive oxygen species productionBlood pressureKidney weightDiabetic ratsKidney failureImmunohistochemical stainingOxygen species productionPodocyte damageBody weightEnzyme inhibitorsWistar albino