2018
Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time
Forest M, O'Donnell KJ, Voisin G, Gaudreau H, MacIsaac JL, McEwen LM, Silveira PP, Steiner M, Kobor MS, Meaney MJ, Greenwood CMT. Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time. Epigenetics 2018, 13: 19-32. PMID: 29381404, PMCID: PMC5837078, DOI: 10.1080/15592294.2017.1411443.Peer-Reviewed Original ResearchBrain-Derived Neurotrophic FactorCanadaCatechol O-MethyltransferaseDNA MethylationDried Blood Spot TestingEpigenesis, GeneticFemaleHumansMaleMouth MucosaNetherlandsOligonucleotide Array Sequence AnalysisReceptors, Dopamine D2Receptors, Dopamine D4Receptors, OxytocinReproducibility of ResultsSerotonin Plasma Membrane Transport ProteinsTime Factors
2015
funtooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types
Oros Klein K, Grinek S, Bernatsky S, Bouchard L, Ciampi A, Colmegna I, Fortin JP, Gao L, Hivert MF, Hudson M, Kobor MS, Labbe A, MacIsaac JL, Meaney MJ, Morin AM, O'Donnell KJ, Pastinen T, Van Ijzendoorn MH, Voisin G, Greenwood CM. funtooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types. Bioinformatics 2015, 32: 593-595. PMID: 26500152, PMCID: PMC4743629, DOI: 10.1093/bioinformatics/btv615.Peer-Reviewed Original ResearchMeSH KeywordsAutoimmune DiseasesCell LineageDiabetes, GestationalDNA MethylationFemaleHumansOligonucleotide Array Sequence AnalysisOrgan SpecificityPregnancySoftwareConceptsMethylation patternsIllumina Infinium Human Methylation450 BeadChipDNA methylation patternsBenefits of cellsDNA methylation dataTissue typesR packageInter-tissue variabilityMethylation dataChromosome XCell typesNew R packageNormalization of dataMore cellsCellsMultiple cellsCross-validated errorBeadChipBioconductor