Active companies in the New Haven area, and their founders

Achillion Pharmaceuticals 
Innovative treatments for infectious diseases (
Yung-Chi Cheng, Ph.D., Henry Bronson Professor of Pharmacology

Affomix Corporation
Antibody screening technology
Michael Snyder, Ph.D., former Lewis B. Cullman Professor of Molecular, Cellular, and Developmental Biology and professor of molecular biophysics and chemistry

Alexion Pharmaceuticals
Treatments for rare diseases (
Leonard Bell, M.D. ’84, former assistant clinical professor of medicine and pathology
Joseph A. Madri, M.D., Ph.D., HS ’76, professor of pathology

Applied Spine Technologies 
Spinal implant device
Manohar M. Panjabi, Ph.D., professor emeritus of orthopaedics and rehabilitation

Axerion Therapeutics
Treatments for spinal cord injury and Alzheimer disease
Stephen M. Strittmatter, M.D., Ph.D., Vincent Coates Professor of Neurology and professor of neurobiology

Antibiotic discovery
Ronald Breaker, Ph.D., Henry Ford II Professor of Molecular, Cellular, and Developmental Biology

Carigent Therapeutics
Drug delivery technology
W. Mark Saltzman, Ph.D., chair and Goizueta Foundation Professor of Chemical and Biomedical Engineering
Tarek Fahmy, Ph.D., assistant professor of biomedical engineering

CGI Pharmaceuticals 
Kinase drug discovery
David Armistead, Ph.D.
Mark Velleca, M.D., Ph.D., HS ’97, FW ’99, assistant clinical professor of laboratory medicine
Ira Mellman, Ph.D., former Sterling Professor of Cell Biology and Immunology

CoolSpine LLC
Cooling catheter for use in cardiothoracic surgery
John A. Elefteriades, M.D. ’76, HS ’81, FW ’83, William W.L. Glenn Professor of Surgery

Helix Therapeutics
Genetic repair therapies
Peter M. Glazer, M.D., Ph.D., Robert E. Hunter Professor of Therapeutic Radiology

Quantitative histopathology testing and diagnostics (
David L. Rimm, M.D., Ph.D., professor of pathology
Robert L. Camp, M.D. ’97, Ph.D., associate research scientist in pathology

JS Genetics
Genetic tests for Turner’s syndrome and dyslexia (
Jeffrey R. Gruen, M.D., associate professor of pediatrics (neonatology), investigative medicine, and genetics
Allen E. Bale, M.D., professor of genetics
Scott A. Rivkees, M.D., professor of pediatrics (pediatric developmental biology and biophysics)

L2 Diagnostics
Infectious disease diagnostics 
Erol Fikrig, M.D., Waldemar Von Zedtwitz Professor of Medicine
Joseph E. Craft, M.D., professor of medicine (rheumatology) and immunobiology
Richard A. Flavell, Ph.D., chair and Sterling Professor of Immunobiology

Marinus Pharmaceuticals 
Therapeutics for psychiatric disorders (
Vincent A. Pieribone, Ph.D., associate professor of physiology

MGS Research Inc.
Medical gel dosimetry systems (
Marek J. Maryanski, Ph.D.
John C. Gore, Ph.D., former professor of psychology
Robert J. Schulz, Ph.D., professor emeritus of therapeutic radiology

Cancer diagnostics
Frank Slack, Ph.D., associate professor of molecular, cellular, and developmental biology
Joanne B. Weidhaas, M.D., Ph.D., assistant professor of therapeutic radiology

New Haven Pharmaceuticals 
Therapeutics for depression and GI disorders (
John H. Krystal, M.D. ’84, HS ’88, Robert L. McNeil, Jr., Professor of Clinical Pharmacology
John P. Geibel, M.D., Ds.C., professor of surgery (gastroenterology) and cellular and molecular physiology
Wajahat Z. Mehal, Ph.D., assistant professor of medicine (digestive diseases)
Gerard Sanacora, M.D., Ph.D., assistant professor of psychiatry
Vladimir Coric, M.D., associate clinical professor of psychiatry

Therapeutics and diagnostics for age-related macular degeneration
Josephine J. Hoh, Ph.D., associate professor of epidemiology and ophthalmology

PGxHealth, a division of Clinical Data
Biomarker discovery and drug development (
Gualberto Ruaño, M.D. ’97, Ph.D. ’97

Traditional Chinese botanical remedies developed into FDA-approved drugs for cancer (
Yung-Chi “Tommy” Cheng, Ph.D., Henry Bronson Professor of Pharmacology

Rib-X Pharmaceuticals
Antibiotic drug discovery and development (
Thomas A. Steitz, Ph.D., Sterling Professor of Molecular Biophysics and Biochemistry (and co-recipient of the 2009 Nobel Prize in Chemistry)
Peter B. Moore, Ph.D., Sterling Professor of Chemistry and professor of molecular biophysics and biochemistry
William L. Jorgensen, Ph.D., Sterling Professor of Chemistry

Ovarian cancer diagnostics for Chinese market
Gil G. Mor, M.D., M.Sc., Ph.D., associate professor of obstetrics, gynecology, and reproductive services

Vascular Insights LLC
ClariVein catheter for treating varicose veins (
John P. Marano Jr., Ph.D. ’69
Michael Tal, M.D., associate professor of radiology