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Grants and contracts awarded to Yale School of Medicine

Medicine@Yale, 2008 - Nov Dec


January/February 2008


  • Serap Aksoy, NIH, Evolutionary Genetics of Tsetse and its Symbionts, 5 years, $3,609,045
  • Norma Andrews, NIH, Lysosome-Mediated Cell Invasion by Trypanosoma cruzi, 5 years, $2,549,132
  • Lauren Cohn, NIH, Airway Inflammation-Related Inhibition of Disease (AIRID), 5 years, $1,654,270
  • Joseph Craft, NIH, Dissecting the Role for IL-15 in CD8+ T Cell Homeostasis in Human Lupus, 5 years, $1,654,480
  • Tore Eid, NIH, Dysregulation of Glutamine Synthetase in Human Temporal Lobe Epilepsy, 5 years, $866,750
  • Peter Glazer, NIH, Hypoxia, Genetic Instability and DNA Mismatch Repair, 5 years, $1,853,968
  • Jeffrey Gruen, NIH, Discovery of the 6p21.3 Reading Disability Gene, 3 years, $1,999,501
  • Ya Ha, NIH, Structural Studies of Intramembrane Protease GlpG, 4 years, $1,256,220
  • James Hebda, NIH, Investigating IAPP Aggregation and Toxicity Using Small Molecule Interference, 3 years, $91,673
  • Mark Hochstrasser, NIH, Function and Assembly of Eukaryotic Proteasome, 4 years, $1,179,381
  • Stanimir Ivanov, NIH, Analysis of F-Box Domain Containing Effector Proteins from Legionella pneumophila, 2 years, $96,472
  • Leslie Jacobsen, NIH, Reward-Motivated Learning in Adolescent Cannabis Users, 2 years, $421,754
  • James Leckman, NIH, rTMS For Adults with Severe Tourette Syndrome, 2 years, $423,620
  • David McCormick, NIH, Properties of Axons and Synaptic Communication in the Neocortex, 4 years, $1,468,281
  • Andrew Miranker, NIH, Fibrillogenesis Pathways in Diabetes and Renal Diseases, 1 year, $135,571
  • Michael Nitabach, NIH, Calcium Signaling in Circadian Clock Neurons, 5 years, $1,763,529
  • Justin Peacock, NIH, Arg Coordinates Contractile Forces with Adhesion Dynamics in Migrating Neurons, 3 years, $91,673
  • John Rose, NIH, Development of VSV/HIV Recombinants as HIV Vaccines, 5 years, $1,654,500
  • Gerald Shadel, NIH, Nuclear Control of Mitochondrial Gene Expression, 4 years, $1,489,032
  • Richard Shiffman, Agency for Health Care Research and Quality (AHRQ), Clinical Decision Support Services, 2 years, $2,460,732
  • Mehmet Sofuoglu, NIH, Human Laboratory Studies for Stimulant Addiction, 5 years, $631,800
  • Uhna Sung, NIH, A Proteomic Analysis of Norepinephrine Transporters, 1 year, $75,206
  • Elisabetta Ullu, NIH, Small RNAs and their Role in Trypanosome Biology, 5 years, $1,861,313
  • Vinzenz Unger, NIH, Structural Biology of Presynaptic Scaffolds, 1 year, $165,292


  • Albert Ayoub, Robert Leet and Clara Guthrie Patterson Trust, Primitive Cortical Networks, 2 years, $106,000
  • Allen Bale, Breast Cancer Alliance, Inc., Novel Chemopreventive Agents for Hereditary Breast Cancer, 1 year, $100,000
  • Vineet Bhandari, American Thoracic Society, Role of Angiopoietin-2 in Hyperoxia-Induced Lung Injury in the Newborn, 2 years, $100,000
  • Donald Botta, CoolSpine, LLC., Intraventricular Cooling Catheter, 1 year, $33,222
  • Elizabeth Bradley, United Health Foundation, Hospital Variation in Survival Rates after Acute Myocardial Infarction, 3 years, $300,000; The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Diffusion of Hospital Strategies to Improve Care for Heart Attacks: How and Why do Organizations Learn?, 1 year, $55,000
  • Owen Chan, Juvenile Diabetes Research Foundation International, Role of GABA in Modulation of Counterregulatory Responses to Hypoglycemia, 2 years, $110,000
  • Joseph Craft, Arthritis Foundation, A Novel T Cell Subset That Promotes Autoimmune Responses, 2 years, $200,000
  • Larry Davidson, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Restoring Hope and Health to Adults with Serious Mental Illness, 3 years, $360,000
  • Sabrina Diano, American Diabetes Association, Inc., Role of Arcuate AMPK on Energy Metabolism, 3 years, $300,000
  • David Donnelly, Arkansas Children’s Hospital Research Institute, Postnatal Resetting of Carotid Chemoreceptor Sensitivity, 1 year, $347,277
  • Eloise Dray, Susan G. Komen Breast Cancer Foundation, Molecular Basis of BRCA2-Mediated Repair of Chromosome Damage, 3 years, $135,000
  • Naomi Driesen, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Prefrontal Development in Youths at Risk for Schizophrenia, 2 years, $239,956
  • Michelle Erickson, College of American Pathologists Foundation, Evaluation of Usage Pattern of Fresh Frozen Plasma in a Tertiary Teaching Hospital Before and After an Interventional Program Initiated by the Transfusion Committee, 1 year, $9,545
  • Matia Finn-Stevenson, Independence Public Schools, Evaluation Design of Three Middle-Childhood Before- and After-School Programs, 1 year, $45,000
  • John Forrest, Doris Duke Charitable Foundation, Doris Duke Charitable Foundation Clinical Research Fellowship (CRF), 3.5 years, $900,000
  • Qian Gao, American Diabetes Association, Inc., Crosstalk Between Estrogen and Leptin Signaling, 3 years, $300,000
  • Nora Groce, Padua University Medical School, Investing for Health: Addressing the Social Determinants of Health, 2 months, $7,000
  • Marsha Guess, Robert Wood Johnson Foundation, Vaginal Smooth Muscle Cell Differentiation in Pelvic Organ Prolapse, 4 years, $416,558
  • Handan Gunduz-Bruce, National Alliance for Research on Schizophrenia and Depression, Modeling Glial Dysfunction in Psychotic and Mood Disorders, 2 years, $60,000
  • Matija Hedl, Crohn’s & Colitis Foundation of America Inc., Nod2-Mediated Self-Tolerance and Cross-Tolerance to Toll-Like Receptors 2 and 4, 2 years, $57,447
  • Robert Heimer, State of CT Dept. of Public Health, Preventing HIV and Other Infection by Expanding Syringe Access over the Counter and by Prescription, 2.5 years, $166,290
  • Mark Horowitz, Maine Medical Center Research Institute, Mouse Models to Delineate a Unique Metabolic and Skeletal Network, 1 year, $144,644
  • Tamas Horvath, Michael J. Fox Foundation for Parkinson’s Research, Ghrelin Protects Nigral Dopamine Cells, 1 year, $75,000
  • Richard Kibbey, American Diabetes Association, Inc., Interaction of Mitochondrial GTP, Calcium and Anaplerotic Metabolism to Regulate Insulin Secretion, 3 years, $414,000
  • Donald Lannin, Susan G. Komen Breast Cancer Foundation, Molecular Definition of DCIS that has Become Invasive, 2 years, $1,465,856
  • Qiang Leng, American Heart Association, National Center, Identification, Characterization and Regulation of Intermediate Conductance 70 pS K Channel in Kidney, 4 years, $308,000
  • Richard Lifton, Fondation Leducq, Transatlantic Network on Hypertension: Renal Salt Handling in the Control of Blood Pressure, 1 year, $3,000,000
  • Yilun Liu, Breast Cancer Alliance, Inc., Understanding the Role of RAD51C Complexes in DNA Repair and Tumor Avoidance, 2 years, $125,000
  • Paul Lombroso, Wesleyan University, Regulation of Epileptogenesis by STEP, 1 year, $16,089
  • Jinyu Lu, American Cancer Society, Inc., Deciphering the Genetic Basis of Tumor Metastasis in Drosophila, 2 years, $94,000
  • Shuangge Ma, University of Iowa, Regularized Classification and Survival Analysis for Expression Profiling of Cancer,
    4 years, $306,420
  • Mark Mamula, Juvenile Diabetes Research Foundation International, Post-Transitional Protein Modifications in
    Diabetes Autoantigens
    , 1 year, $110,000
  • Wang Min, AtheroGenics, Inc., Atherogenics Testing Agreement, 1 year, $19,860
  • Yorgo Modis, The Lupus Research Institute, The Structural Basis of Endogenous Nucleic Acid Recognition by Toll-Like Receptors 7 and 9, 3 years, $300,000
  • Alexander Neumeister, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Contribution of Life Trauma to the Neurobiology of Depression, 5 years, $467,110
  • Jennifer Prah Ruger, The Patrick and Catherine Weldon Donaghue Medical Research Foundation, Ethics and Economics of Healthcare Disparities, 5 years, $595,796
  • Lynne Regan, Breast Cancer Alliance, Inc., Novel Hsp90 Inhibitors as Potential Anti-Breast Cancer Agents, 1 year, $100,000
  • Lei Song, National Organization for Hearing Research Foundation, Cable Properties of Outer Hair Cell Cylinder, 1 year, $20,000
  • Mario Strazzabosco, PKD Foundation for Research in Polycystic Kidney Disease, Angiogenesis and Progression of Liver Cysts in ADPKD, 2 years, $150,000
  • Mary Tinetti, John A. Hartford Foundation, Hartford Foundation Center of Excellence in Aging at Yale, 5 years, $750,000
  • Christopher Tormey, College of American Pathologists Foundation, The Development of a Laboratory-Based Assay for the Identification and Evaluation of Transfusion Reactions, 1 year, $10,000
  • Hong Wang, William J. Clinton Foundation, Expert Advice on Non-ARV Costs, China, 6 months, $27,500
  • Tong Wang, Research Foundation of State University of New York, Cytoskeletal Mechanisms of the Epithelial Mesenchymal Transition Induced by the Receptor for Advanced Glycation End Products: The Role in Diabetic Kidney Disease, 1 year, $16,027
  • Lauren Zenewicz, American Cancer Society, Inc., The Role of the Cytokine IL-22 in Liver Inflammation, 2 years, $94,000
  • Edward Zigler, Foundation for Child Development, PCD Book, 1 year, $12,500