https://medicine.yale.edu/ysm/news-rss/?title=Top%20Stories&orgId=113592&keywordId=7 A selection of the latest research, academic, and other newsworthy developments at Yale School of Medicine en-us Copyright 2026 Yale School of Medicine Fri, 05 Jun 2026 22:28:21 Z https://www.yalemedicine.org/news/yale-medicine-takes-top-spots-in-national-state-rankings https://www.yalemedicine.org/news/yale-medicine-takes-top-spots-in-national-state-rankings Yale Medicine was ranked third in the nation for physician practices, an annual designation by Castle Connolly, a health care research company that recognizes doctors considered the best in their specialty. Mon, 02 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/answering-a-century-old-question-how-do-brain-oscillations-emerge/ https://medicine.yale.edu/news-article/answering-a-century-old-question-how-do-brain-oscillations-emerge/ Yale researchers developed a new method for measuring oscillations in neuronal activity. It could help identify early biomarkers of Alzheimer’s disease. Wed, 08 Oct 2025 15:00:00 Z https://medicine.yale.edu/news-article/brain-navigates-new-spaces-by-flickering-between-reality-and-old-mental-maps/ https://medicine.yale.edu/news-article/brain-navigates-new-spaces-by-flickering-between-reality-and-old-mental-maps/ A new Yale study reveals the brain's internal map doesn't just track one’s current location, it constantly "flickers" between the present space and remembered alternatives. Fri, 03 Oct 2025 12:00:00 Z https://medicine.yale.edu/news-article/brain-network-active-at-birth-linked-to-social-behavior-later-in-life/ https://medicine.yale.edu/news-article/brain-network-active-at-birth-linked-to-social-behavior-later-in-life/ A brain network linked to social attention is functional in newborns, a Yale study finds. It may underlie some of the social vulnerabilities associated with autism. Wed, 01 Oct 2025 14:00:00 Z https://medicine.yale.edu/news-article/brain-activity-variable-during-development/ https://medicine.yale.edu/news-article/brain-activity-variable-during-development/ Fluctuations in brain activity increase until mid-adolescence. Deviations from this trajectory are linked to worse executive functioning. Mon, 22 Sep 2025 16:00:00 Z https://medicine.yale.edu/news-article/glp-1-receptor-agonists-protect-the-liver-during-alcohol-consumption/ https://medicine.yale.edu/news-article/glp-1-receptor-agonists-protect-the-liver-during-alcohol-consumption/ New findings suggest GLP-1 receptor agonists like Ozempic reduce alcohol metabolism and its toxic metabolites. But they may also raise blood alcohol levels. Thu, 18 Sep 2025 19:00:00 Z https://medicine.yale.edu/news-article/how-an-essential-vitamin-b-derived-nutrient-concentrates-in-mitochondria/ https://medicine.yale.edu/news-article/how-an-essential-vitamin-b-derived-nutrient-concentrates-in-mitochondria/ Researchers have uncovered why the essential nutrient CoA is largely found in mitochondria. It could help us understand a number of diseases. Mon, 15 Sep 2025 16:00:00 Z https://medicine.yale.edu/news-article/a-new-paradigm-for-understanding-social-cognition/ https://medicine.yale.edu/news-article/a-new-paradigm-for-understanding-social-cognition/ A new approach reveals the sophisticated social strategies marmosets use to cooperate. It may also shed light on how social cognition goes awry in conditions like autism. Wed, 03 Sep 2025 15:00:00 Z https://news.yale.edu/2025/08/26/giving-mrna-vaccines-technological-shot-arm https://news.yale.edu/2025/08/26/giving-mrna-vaccines-technological-shot-arm Yale researchers have created a new technology to maximize the effectiveness and reach of mRNA vaccines.  Tue, 26 Aug 2025 20:00:00 Z https://medicine.yale.edu/news-article/treating-preventing-obesity-obesity-related-conditions/ https://medicine.yale.edu/news-article/treating-preventing-obesity-obesity-related-conditions/ A new research letter by an interdisciplinary Yale School of Medicine team estimates the extent to which obesity-related conditions are attributable to obesity and overweight in adolescents and young adults in the United States. Mon, 25 Aug 2025 15:00:00 Z https://medicine.yale.edu/news-article/how-hiv-uses-t-cells-to-hide-in-the-gut/ https://medicine.yale.edu/news-article/how-hiv-uses-t-cells-to-hide-in-the-gut/ Yale researchers identified a transcription factor that creates a perfect haven for HIV to hide. It could be a target for clearing the virus. Thu, 21 Aug 2025 15:00:00 Z https://medicine.yale.edu/news-article/genetic-study-yields-personalized-therapeutics-for-a-rare-skin-disorder/ https://medicine.yale.edu/news-article/genetic-study-yields-personalized-therapeutics-for-a-rare-skin-disorder/ Keith Choate, MD, PhD, Aaron B. and Marguerite Lerner Professor and Chair of Dermatology and professor of genetics and pathology, led a study that found that cancer medications could be used to treat a rare type of ichthyosis. Thu, 21 Aug 2025 04:00:00 Z https://news.yale.edu/2025/07/18/study-finds-link-between-hypertension-and-breastfeeding-outcomes https://news.yale.edu/2025/07/18/study-finds-link-between-hypertension-and-breastfeeding-outcomes A new Yale study suggests women with high blood pressure before and during pregnancy may benefit from targeted interventions to support breastfeeding. Fri, 18 Jul 2025 18:00:00 Z https://medicine.yale.edu/news-article/for-heart-transplant-patients-blood-test-may-detect-rejection-earlier-and-more-easily/ https://medicine.yale.edu/news-article/for-heart-transplant-patients-blood-test-may-detect-rejection-earlier-and-more-easily/ A new study suggests that cell messengers known as exosomes from transplanted hearts and T cells could be biomarkers for early detection of organ rejection. Thu, 26 Jun 2025 14:00:00 Z https://news.yale.edu/2025/06/23/screen-saver-simpler-less-costly-virus-testing-high-risk-settings https://news.yale.edu/2025/06/23/screen-saver-simpler-less-costly-virus-testing-high-risk-settings Screening for an immunological biomarker in the nasal passage can effectively rule out a respiratory virus—reducing the need for conventional PCR tests. Tue, 24 Jun 2025 13:00:00 Z https://medicine.yale.edu/news-article/consuming-less-cysteine-can-burn-fat-to-induce-weight-loss/ https://medicine.yale.edu/news-article/consuming-less-cysteine-can-burn-fat-to-induce-weight-loss/ Reducing calorie intake can improve health and longevity. A new study finds the amino acid cysteine may be a key reason why. Tue, 03 Jun 2025 09:00:00 Z https://medicine.yale.edu/news-article/understanding-how-a-rare-brain-wasting-disease-hides-in-neurons-for-decades/ https://medicine.yale.edu/news-article/understanding-how-a-rare-brain-wasting-disease-hides-in-neurons-for-decades/ A neuronal model of Creutzfeldt-Jakob disease begins to reveal how latent infections activate and trigger neurological decline. Wed, 28 May 2025 18:00:00 Z https://medicine.yale.edu/news-article/t-cells-take-up-residence-in-the-healthy-brain-via-a-gut-fat-brain-axis/ https://medicine.yale.edu/news-article/t-cells-take-up-residence-in-the-healthy-brain-via-a-gut-fat-brain-axis/ A Yale study finds specialized immune cells in the brains of mice and humans in the absence of disease, questioning previous dogma about interactions between the brain and the immune system. Wed, 28 May 2025 15:00:00 Z https://medicine.yale.edu/news-article/singing-to-babies-improves-their-moods/ https://medicine.yale.edu/news-article/singing-to-babies-improves-their-moods/ A new study highlights how singing is a simple yet effective way to support infant well-being. Wed, 28 May 2025 07:01:00 Z https://news.yale.edu/research-greater-good https://news.yale.edu/research-greater-good Yale research makes America stronger, safer, and healthier. Fri, 23 May 2025 12:00:00 Z https://medicine.yale.edu/news-article/understanding-one-genes-role-in-different-neurodevelopmental-disorders/ https://medicine.yale.edu/news-article/understanding-one-genes-role-in-different-neurodevelopmental-disorders/ A new Yale study reveals how variations in one gene related to intellectual disability, autism, schizophrenia, and related disorders alter behavior and neuron function. Wed, 21 May 2025 12:00:00 Z https://medicine.yale.edu/news-article/md-class-of-2025-ready-to-ignite-the-world-they-want-to-see/ https://medicine.yale.edu/news-article/md-class-of-2025-ready-to-ignite-the-world-they-want-to-see/ The ability of the Yale School of Medicine (YSM) MD Class of 2025 to change the world for the better was a common theme at its May 19 Commencement ceremony. Family and friends of the 87 graduates, along with YSM faculty, students, and staff, filled Amistad Park for the occasion. Mon, 19 May 2025 04:00:00 Z https://news.yale.edu/2025/05/09/how-typhoid-fever-triggers-severe-neurological-symptoms https://news.yale.edu/2025/05/09/how-typhoid-fever-triggers-severe-neurological-symptoms Yale researchers have discovered how typhoid fever triggers neurological symptoms, offering new insight into treatment options.  Fri, 09 May 2025 15:00:00 Z https://medicine.yale.edu/news-article/beloved-yale-school-of-medicine-professor-leaves-dollar9-million-bequest-to-yale/ https://medicine.yale.edu/news-article/beloved-yale-school-of-medicine-professor-leaves-dollar9-million-bequest-to-yale/ A $9 million bequest from the late Joseph Frederick Hoffman, PhD, Eugene Higgins Professor Emeritus of Cellular and Molecular Physiology at Yale School of Medicine (YSM), will establish funds to support research, students, patients, and more. Tue, 06 May 2025 13:00:00 Z https://medicine.yale.edu/news-article/skin-injury-may-bring-on-food-allergies/ https://medicine.yale.edu/news-article/skin-injury-may-bring-on-food-allergies/ A Yale lab links skin inflammation to the development of food allergies via a skin-gut connection, suggesting clues to a little-understood immune reaction. Fri, 04 Apr 2025 18:00:00 Z https://news.yale.edu/2025/03/26/how-inherited-cancer-risks-can-be-used-effective-personalized-therapy https://news.yale.edu/2025/03/26/how-inherited-cancer-risks-can-be-used-effective-personalized-therapy A new study co-led by scientists at Yale and NYU reveals a novel mechanism linking genetic mutations and cancer drug efficacy.  Thu, 27 Mar 2025 04:00:00 Z https://medicine.yale.edu/news-article/yale-researchers-advance-work-in-diagnosing-and-preventing-tickborne-diseases/ https://medicine.yale.edu/news-article/yale-researchers-advance-work-in-diagnosing-and-preventing-tickborne-diseases/ New research led by Yale School of Medicine advances the goals of creating a diagnostic test and vaccines for tick-borne diseases. The study was published March 26 in Science Translational Medicine. Wed, 26 Mar 2025 19:00:00 Z https://medicine.yale.edu/news-article/protein-turnover-mapping-may-offer-clues-for-alzheimers-cancer-treatment/ https://medicine.yale.edu/news-article/protein-turnover-mapping-may-offer-clues-for-alzheimers-cancer-treatment/ Protein turnover is essential for cellular health. Yale researchers have now determined protein turnover across several tissue types, uncovering potential targets for treating Alzheimer’s disease and cancer. Thu, 20 Mar 2025 15:00:00 Z https://news.yale.edu/2025/03/20/new-crispr-tool-enables-more-seamless-gene-editing-and-improved-disease-modeling https://news.yale.edu/2025/03/20/new-crispr-tool-enables-more-seamless-gene-editing-and-improved-disease-modeling Yale scientists have developed a CRISPR technology that can assess genetic interactions on a host of immunological responses to multiple diseases, including cancer. Thu, 20 Mar 2025 10:00:00 Z https://medicine.yale.edu/news-article/harnessing-the-power-of-biomedical-data-while-protecting-privacy/ https://medicine.yale.edu/news-article/harnessing-the-power-of-biomedical-data-while-protecting-privacy/ In an interview, Yale’s Hyunghoon Cho discusses his research on how to make the most of biomedical data while ensuring its security. Fri, 14 Mar 2025 16:00:00 Z https://news.yale.edu/2025/03/14/seizures-and-driving-roadmap-protecting-public-health-and-individual-rights https://news.yale.edu/2025/03/14/seizures-and-driving-roadmap-protecting-public-health-and-individual-rights In an interview, Yale neurologist Benjamin Tolchin discusses a new consensus statement he co-authored on seizures, driver licensure, and medical reporting. Fri, 14 Mar 2025 16:00:00 Z https://medicine.yale.edu/news-article/a-new-approach-to-alzheimers-study-finds-promising-therapeutic-target/ https://medicine.yale.edu/news-article/a-new-approach-to-alzheimers-study-finds-promising-therapeutic-target/ Axonal spheroids may contribute to Alzheimer’s disease by hindering neuronal communication. Researchers have found a way to shrink them. Mon, 10 Mar 2025 10:00:00 Z https://medicine.yale.edu/news-article/new-insights-into-preterm-infant-immunity-could-inform-care/ https://medicine.yale.edu/news-article/new-insights-into-preterm-infant-immunity-could-inform-care/ By developing new methods that extract a lot of data from a small amount of blood, Yale researchers are getting the first look at how immune systems develop in extremely preterm infants. Wed, 05 Mar 2025 19:00:00 Z https://news.yale.edu/2025/03/03/scientists-discover-how-naturally-occurring-mechanism-hampers-fertility https://news.yale.edu/2025/03/03/scientists-discover-how-naturally-occurring-mechanism-hampers-fertility A new Yale study describes a key mechanism that blocks egg-sperm fertilization. Mon, 03 Mar 2025 05:00:00 Z https://medicine.yale.edu/news-article/yale-researchers-use-large-language-models-to-detect-gastrointestinal-bleeding/ https://medicine.yale.edu/news-article/yale-researchers-use-large-language-models-to-detect-gastrointestinal-bleeding/ A team of Yale researchers demonstrated the effectiveness of a large language model (LLM)-based pipeline in identifying overt gastrointestinal bleeding in 1,108 patients seen between 2014 and 2023 in Yale New Haven Health. The study showed a high accuracy of the model in detecting melena, hematochezia, and hematemesis, identifying recurrent bleeding, and catching more than 98% of cases. The algorithm also increased the average per-patient reimbursement. Fri, 28 Feb 2025 05:00:00 Z https://medicine.yale.edu/news-article/the-rules-of-immunity-what-decides-t-cell-fate/ https://medicine.yale.edu/news-article/the-rules-of-immunity-what-decides-t-cell-fate/ Yale researchers have identified a lever that determines the fate of T cells, influencing whether they become killer cells or exhausted cells during an immune response. Thu, 27 Feb 2025 05:00:00 Z https://medicine.yale.edu/news-article/ysm-moves-up-to-3rd-in-us-for-nih-funding/ https://medicine.yale.edu/news-article/ysm-moves-up-to-3rd-in-us-for-nih-funding/ Yale School of Medicine now ranks third in the nation for NIH funding, according to the most recent report from the Blue Ridge Institute for Medical Research. Tue, 25 Feb 2025 05:00:00 Z https://news.yale.edu/2025/02/25/canvas-clinic-med-students-study-art-sharpen-critical-thinking https://news.yale.edu/2025/02/25/canvas-clinic-med-students-study-art-sharpen-critical-thinking The Yale School of Medicine celebrates the 10th anniversary of “Making the Invisible Visible,” a program that uses Yale’s art collections as part of medical training. Tue, 25 Feb 2025 05:00:00 Z https://news.yale.edu/2025/02/19/immune-markers-post-vaccination-syndrome-indicate-future-research-directions https://news.yale.edu/2025/02/19/immune-markers-post-vaccination-syndrome-indicate-future-research-directions A small number of people report chronic symptoms after receiving COVID-19 shots. A new study provides clues for further research. Wed, 19 Feb 2025 05:00:00 Z https://medicine.yale.edu/news-article/gut-microbiome-changes-linked-to-multiple-sclerosis-ms-new-study-finds/ https://medicine.yale.edu/news-article/gut-microbiome-changes-linked-to-multiple-sclerosis-ms-new-study-finds/ The gut microbiomes of individuals with multiple sclerosis (MS) have fewer bacteria coated with the host antibody immunoglobulin A (IgA), a new study finds. Tue, 18 Feb 2025 05:00:00 Z https://medicine.yale.edu/news-article/the-future-of-gene-editing-treatments-for-rare-diseases/ https://medicine.yale.edu/news-article/the-future-of-gene-editing-treatments-for-rare-diseases/ New gene-editing treatments being developed at Yale School of Medicine give hope to those with rare genetic diseases, such as Angelman syndrome. Mon, 17 Feb 2025 05:00:00 Z https://news.yale.edu/2025/02/13/feet-first-understanding-how-mrna-helps-cells-walk https://news.yale.edu/2025/02/13/feet-first-understanding-how-mrna-helps-cells-walk Yale researchers have uncovered a new role for mRNA — being part of the “feet” that allow cells to move around the body. Thu, 13 Feb 2025 05:00:00 Z https://news.yale.edu/2025/02/10/brown-reappointed-dean-yale-school-medicine https://news.yale.edu/2025/02/10/brown-reappointed-dean-yale-school-medicine During her first term, Dr. Nancy J. Brown advanced the school’s mission and elevated its reputation nationally and globally, university leaders said. Tue, 11 Feb 2025 05:00:00 Z https://medicine.yale.edu/news-article/why-opioid-use-disorder-oud-may-contribute-to-preterm-birth/ https://medicine.yale.edu/news-article/why-opioid-use-disorder-oud-may-contribute-to-preterm-birth/ The opioid buprenorphine is linked to increased inflammation and weakening of the fetal membrane, researchers found. Tue, 11 Feb 2025 05:00:00 Z https://medicine.yale.edu/news-article/health-care-company-payouts-favor-shareholders-new-research-shows/ https://medicine.yale.edu/news-article/health-care-company-payouts-favor-shareholders-new-research-shows/ Most of health care companies’ net income goes to shareholders, according to a research letter recently published in JAMA Internal Medicine. Mon, 10 Feb 2025 05:00:00 Z https://news.yale.edu/2025/02/05/study-reveals-how-gut-bacteria-might-trigger-autoimmune-diseases-lupus https://news.yale.edu/2025/02/05/study-reveals-how-gut-bacteria-might-trigger-autoimmune-diseases-lupus Gut bacteria are increasingly implicated in non-gut-related autoimmune diseases. Yale researchers have begun to understand how they’re connected. Fri, 07 Feb 2025 05:00:00 Z https://news.yale.edu/2025/02/06/yale-scientists-recode-genome-programmable-synthetic-proteins https://news.yale.edu/2025/02/06/yale-scientists-recode-genome-programmable-synthetic-proteins A team of synthetic biologists have re-written the genetic code of an organism using a novel cellular platform for producing new classes of synthetic proteins. Thu, 06 Feb 2025 05:00:00 Z https://news.yale.edu/2025/02/06/study-sheds-light-genetic-changes-shaped-human-brain-evolution https://news.yale.edu/2025/02/06/study-sheds-light-genetic-changes-shaped-human-brain-evolution A new Yale study reveals how a class of genetic switches altered genes shared by humans and chimpanzees, and identified more genes that were targeted in the process. Thu, 06 Feb 2025 05:00:00 Z https://medicine.yale.edu/news-article/mehra-golshan-to-receive-the-ellis-island-medal-of-honor/ https://medicine.yale.edu/news-article/mehra-golshan-to-receive-the-ellis-island-medal-of-honor/ Golshan was awarded the 2025 Ellis Island Medal of Honor from the Ellis Island Honors Society on May 10, 2025. The medal recognizes Golshan’s contributions to breast cancer treatment and research, his dedication to patient care, and his commitment to mentorship. Wed, 05 Feb 2025 05:00:00 Z https://medicine.yale.edu/news-article/ai-can-identify-cardiomyopathies-early-says-new-study/ https://medicine.yale.edu/news-article/ai-can-identify-cardiomyopathies-early-says-new-study/ AI-assisted testing in emergency rooms could lead to early diagnosis of cardiomyopathies, Yale-led research finds. Fri, 31 Jan 2025 05:00:00 Z