https://medicine.yale.edu/ysm/news-rss/?title=More%20Historical%20Impact%20Stories&orgId=124035&keywordId=1329 A selection of the latest research, academic, and other newsworthy developments at YSM Impact en-us Copyright 2026 Yale School of Medicine Fri, 10 Apr 2026 20:13:05 Z https://medicine.yale.edu/news-article/americas-first-x-ray/ https://medicine.yale.edu/news-article/americas-first-x-ray/ In 1896, Yale physicist Arthur Wright produced one of America’s first X-ray images, helping launch modern medical imaging in the United States. Tue, 24 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/from-penicillin-to-phages-yales-century-long-fight-against-infection/ https://medicine.yale.edu/news-article/from-penicillin-to-phages-yales-century-long-fight-against-infection/ Yale doctors helped save the first U.S. patient treated with penicillin and led early clinical trials—launching America’s antibiotic era. Tue, 24 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/from-erector-set-to-heart-bypass/ https://medicine.yale.edu/news-article/from-erector-set-to-heart-bypass/ In 1948, a Yale medical student built a heart bypass pump, helping lay the foundation for open-heart surgery. Tue, 24 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/how-cells-communicate/ https://medicine.yale.edu/news-article/how-cells-communicate/ Yale research uncovered how vesicles fuse and recycle, revealing core mechanisms of cellular communication. Tue, 24 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/bullseye-how-yale-researchers-identified-lyme-disease/ https://medicine.yale.edu/news-article/bullseye-how-yale-researchers-identified-lyme-disease/ After two Connecticut mothers raised alarms, Yale physicians identified Lyme disease as a tick-borne illness—changing diagnosis and treatment nationwide. Tue, 24 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/ketamine-how-yale-redefined-depression-treatment/ https://medicine.yale.edu/news-article/ketamine-how-yale-redefined-depression-treatment/ Yale psychiatrist John Krystal’s discovery that ketamine rapidly treats depression led to esketamine and transformed mental health care. Tue, 24 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/rna-reimagined/ https://medicine.yale.edu/news-article/rna-reimagined/ Yale scientist Sidney Altman’s discovery of catalytic RNA earned a Nobel Prize and helped shape modern gene editing and RNA medicine. Tue, 24 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/how-yale-helped-create-modern-fetal-medicine/ https://medicine.yale.edu/news-article/how-yale-helped-create-modern-fetal-medicine/ From fetal heart rate monitoring to prenatal genetic diagnosis, Yale innovations helped establish modern multidisciplinary fetal medicine. Tue, 24 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/yale-and-the-birth-of-modern-neonatal-intensive-care/ https://medicine.yale.edu/news-article/yale-and-the-birth-of-modern-neonatal-intensive-care/ In 1960, Yale’s Louis Gluck opened the first NICU in the United States, revolutionizing care for premature and critically ill newborns. Tue, 24 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/stigma-to-science/ https://medicine.yale.edu/news-article/stigma-to-science/ Yale research helped redefine obesity as a chronic metabolic disease and advanced next-generation treatments. Tue, 24 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/the-birth-of-chemotherapy-at-yale-from-wartime-secrecy-to-modern-cancer-care/ https://medicine.yale.edu/news-article/the-birth-of-chemotherapy-at-yale-from-wartime-secrecy-to-modern-cancer-care/ In 1942, Yale scientists treated the first patient with intravenous chemotherapy using nitrogen mustard. The breakthrough—once classified during World War II—helped establish modern cancer treatment. Tue, 24 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/insulin-and-the-first-insulin-pump-how-yale-advanced-diabetes-care/ https://medicine.yale.edu/news-article/insulin-and-the-first-insulin-pump-how-yale-advanced-diabetes-care/ Yale researchers helped develop the first insulin pump, pioneering continuous insulin delivery and modern automated diabetes care. Mon, 23 Feb 2026 05:00:00 Z https://medicine.yale.edu/news-article/genetic-testing-in-hospitals-and-clinics-how-yale-advanced-whole-exome-sequencing/ https://medicine.yale.edu/news-article/genetic-testing-in-hospitals-and-clinics-how-yale-advanced-whole-exome-sequencing/ In 2009, Yale researchers showed whole exome sequencing could deliver rapid genetic diagnoses, accelerating rare disease care and precision medicine. Mon, 23 Feb 2026 05:00:00 Z