https://medicine.yale.edu/ysm/news-rss/?title=Latest%20News&orgId=113592&keywordId=1549 A selection of the latest research, academic, and other newsworthy developments at Yale School of Medicine en-us Copyright 2026 Yale School of Medicine Mon, 13 Apr 2026 02:45:44 Z https://medicine.yale.edu/news-article/surgery-receives-gift-breast-cancer-research-reconstruction/ https://medicine.yale.edu/news-article/surgery-receives-gift-breast-cancer-research-reconstruction/ The gift will fund vital initiatives at YSM, focusing on advancing clinical care, research, and education in breast cancer treatment and reconstruction. Thu, 19 Feb 2026 14:00:00 Z https://medicine.yale.edu/news-article/yale-cancer-center-smilow-cancer-hospital-receive-million-dollar-gift-from-donor-compassionate-patient-care/ https://medicine.yale.edu/news-article/yale-cancer-center-smilow-cancer-hospital-receive-million-dollar-gift-from-donor-compassionate-patient-care/ Daniel M. Koenigsberg, YC ’62, MD, vividly remembers the compassionate care his late wife, Susan, received at Smilow Cancer Hospital while being treated for pancreatic cancer. He recognized this extraordinary patient care delivery by gifting $1 million to Yale Cancer Center and Smilow Cancer Hospital. Fri, 19 Sep 2025 15:00:00 Z https://medicine.yale.edu/news-article/yale-school-of-medicine-receives-dollar1-million-gift-toward-breast-cancer-research/ https://medicine.yale.edu/news-article/yale-school-of-medicine-receives-dollar1-million-gift-toward-breast-cancer-research/ The Yale School of Medicine (YSM) Department of Surgery has received a $1 million gift from Raj and Indra Nooyi to establish the Raj and Indra Nooyi Cancer Research Fund. Thu, 02 Jan 2025 05:00:00 Z https://medicine.yale.edu/news-article/in-the-early-steps-of-cancer-formation-timing-matters/ https://medicine.yale.edu/news-article/in-the-early-steps-of-cancer-formation-timing-matters/ Powerful microscopes at Yale capture the moment cancerous cell mutations begin, pointing to possible new pathways for cancer prevention. Tue, 30 Apr 2024 10:00:00 Z https://medicine.yale.edu/news-article/aasld-liver-cancer-management/ https://medicine.yale.edu/news-article/aasld-liver-cancer-management/ Yale researchers have collaborated with other experts in the field of hepatocellular carcinoma (HCC), or liver cancer, to develop the most recent American Association for the Study of Liver Diseases (AASLD) practice guidance for liver cancer. Mon, 19 Feb 2024 05:00:00 Z https://medicine.yale.edu/news-article/a-promising-treatment-on-the-horizon-for-cancer-related-fatigue/ https://medicine.yale.edu/news-article/a-promising-treatment-on-the-horizon-for-cancer-related-fatigue/ The research team found that a metabolism-targeting drug called dichloroacetate (DCA) helped alleviate CRF in mice, without interfering with cancer treatments. Tue, 03 Oct 2023 04:00:00 Z https://medicine.yale.edu/news-article/ai-more-accurately-identifies-patients-with-advanced-lung-cancer-that-respond-to-immunotherapy-and-helps-doctors-select-treatments/ https://medicine.yale.edu/news-article/ai-more-accurately-identifies-patients-with-advanced-lung-cancer-that-respond-to-immunotherapy-and-helps-doctors-select-treatments/ Researchers compared AI-powered digital scoring with traditional manual scoring of the PD-L1 immune biomarker to determine if a new immunotherapy treatment, atezolizumab, could benefit patients with advanced non-small cell lung cancer. Fri, 08 Sep 2023 13:00:00 Z https://medicine.yale.edu/news-article/new-immunotherapy-treatment-brings-hope-to-patients-with-advanced-non-small-cell-lung-cancer/ https://medicine.yale.edu/news-article/new-immunotherapy-treatment-brings-hope-to-patients-with-advanced-non-small-cell-lung-cancer/ The study's findings suggest that NC318, both alone and in combination with pembrolizumab, improved response rates and clinical outcomes for some patients with NSCLC. Fri, 08 Sep 2023 13:00:00 Z https://medicine.yale.edu/news-article/new-international-study-shows-promise-of-immunotherapy-treatment-for-patients-with-penile-cancer/ https://medicine.yale.edu/news-article/new-international-study-shows-promise-of-immunotherapy-treatment-for-patients-with-penile-cancer/ An international study led by Yale Cancer Center researchers at Yale School of Medicine found that the use of immune checkpoint inhibitors offers promising clinical benefits for some patients with advanced penile squamous cell carcinoma. Fri, 11 Aug 2023 04:00:00 Z https://medicine.yale.edu/news-article/screening-mammograms-for-older-women-carry-risks-studyfinds/ https://medicine.yale.edu/news-article/screening-mammograms-for-older-women-carry-risks-studyfinds/ Although some guidelines recommend continuing screening for older women, this new study emphasizes the importance of assessing potential harms associated with testing, such as overdiagnosis, which, researchers say, can negatively affect quality of life. Mon, 07 Aug 2023 21:00:00 Z https://news.yale.edu/2023/08/03/method-allows-new-insights-interplay-between-immune-system-and-tumors https://news.yale.edu/2023/08/03/method-allows-new-insights-interplay-between-immune-system-and-tumors A new technique will enable researchers to study individual differences in cancer progression and treatment response. Thu, 03 Aug 2023 04:00:00 Z https://medicine.yale.edu/news-article/researchers-develop-a-new-way-to-classify-hpv-associated-head-and-neck-cancers/ https://medicine.yale.edu/news-article/researchers-develop-a-new-way-to-classify-hpv-associated-head-and-neck-cancers/ Researchers have identified a novel subclass of HPV+ head and neck squamous cell carcinoma and demonstrated that treatment could be tailored by tumor type. Mon, 31 Jul 2023 19:00:00 Z https://medicine.yale.edu/news-article/yale-scientists-identify-immune-cells-critical-for-immunologic-memory-for-melanoma/ https://medicine.yale.edu/news-article/yale-scientists-identify-immune-cells-critical-for-immunologic-memory-for-melanoma/ A new study led by Yale Cancer Center researchers at Yale School of Medicine reveals that a specific population of CD8+ T-cells marked by IL-7R play an important role in better understanding anti-tumor memory. Thu, 27 Jul 2023 16:05:00 Z https://news.yale.edu/2023/07/27/tail-spin-study-reveals-new-way-reduce-friendly-fire-cell-therapy https://news.yale.edu/2023/07/27/tail-spin-study-reveals-new-way-reduce-friendly-fire-cell-therapy Many engineered T cells become tainted with the remnants of cancer antigens, which causes them to turn against other T cells. This eventually depletes the body of cancer-fighting cells and opens the door for a recurrence of cancer. A new Yale study, however, has identified a way to tame the self-destructive tendencies of these killer T cells. Thu, 27 Jul 2023 04:00:00 Z https://medicine.yale.edu/news-article/combination-cancer-therapies-can-shrink-tumors-and-improve-survival-outcomes-for-patients-with-advanced-non-small-cell-lung-cancer/ https://medicine.yale.edu/news-article/combination-cancer-therapies-can-shrink-tumors-and-improve-survival-outcomes-for-patients-with-advanced-non-small-cell-lung-cancer/ An ongoing phase II study led by a Yale Cancer Center researcher reveals that combining pembrolizumab with other treatments reduced the size of target tumors, resulting in a higher response rate for patients with advanced NSCLC. Wed, 12 Jul 2023 04:00:00 Z https://news.yale.edu/2023/07/06/eliminating-extra-chromosomes-cancer-cells-prevents-tumor-growth https://news.yale.edu/2023/07/06/eliminating-extra-chromosomes-cancer-cells-prevents-tumor-growth Many cancer cells have too many chromosomes. A new study reveals their role in promoting cancer—and their potential as a new target for treatment. Thu, 06 Jul 2023 04:00:00 Z https://medicine.yale.edu/news-article/pancreatic-cancer-risk-lower-if-pancreatic-cysts-remain-stable-for-five-years/ https://medicine.yale.edu/news-article/pancreatic-cancer-risk-lower-if-pancreatic-cysts-remain-stable-for-five-years/ Low-risk branch duct intraductal papillary mucinous neoplasms (IPMN) are the most common precancerous form of mucinous pancreatic cysts and once identified require regular surveillance imaging. But consensus is still forming around how long that watchful period should last. In a new study, Yale Cancer Center researchers question the health benefit of extended surveillance for patients whose cyst has not changed size for at least five years and has no worrisome features. Fri, 30 Jun 2023 04:00:00 Z https://medicine.yale.edu/news-article/study-hints-at-how-cancer-immunotherapy-can-be-safer/ https://medicine.yale.edu/news-article/study-hints-at-how-cancer-immunotherapy-can-be-safer/ Cancer immunotherapy has revolutionized treatment of many forms of cancer by unleashing the immune system response against tumors. But in some cases, side effects can be severe. Wed, 21 Jun 2023 04:00:00 Z https://medicine.yale.edu/news-article/new-findings-reveal-impact-of-changing-landscape-for-patients-with-cancer-prescribed-opioids/ https://medicine.yale.edu/news-article/new-findings-reveal-impact-of-changing-landscape-for-patients-with-cancer-prescribed-opioids/ In response to the opioid epidemic in the United States, interventions to prevent over-prescribing and misuse of opioids were enacted at institutional, state, and federal levels. To assess how changes in the prescribing landscape affected patients, a research team from the Yale COPPER Center examined the rates of both new and persistent opioid prescribing in patients with cancer as well as in patients without cancer, utilizing data from SEER-Medicare. Wed, 31 May 2023 04:00:00 Z https://medicine.yale.edu/news-article/new-yale-led-study-identifies-bereaved-parents-medical-priorities-for-children-with-advanced-cancer/ https://medicine.yale.edu/news-article/new-yale-led-study-identifies-bereaved-parents-medical-priorities-for-children-with-advanced-cancer/ For families facing the end-of-life of a loved one with pediatric cancer, robust quality measures to benchmark what parents value most in their child’s medical care do not currently exist. A new study from Yale Cancer Center helps identify what parents prioritize for their children with advanced cancer, including alleviating the child’s symptoms and honoring the family’s goals and wishes. Researchers say the findings may help establish a patient-centered agenda for quality measurement and improvement in children with advanced, incurable cancer. The study titled, "Parent Priorities in End-of-Life Care for Children with Cancer,” was published in JAMA Network Open on May 15. Mon, 15 May 2023 04:00:00 Z https://news.yale.edu/2023/03/08/bosenberg-named-brady-professor-dermatology-pathology-and-immunobiology https://news.yale.edu/2023/03/08/bosenberg-named-brady-professor-dermatology-pathology-and-immunobiology Dr. Marcus Bosenberg, an accomplished clinician, teacher, and researcher who studies the factors that regulate anti-cancer immune responses, was recently appointed the Anthony N. Brady Professor of Dermatology, Pathology, and Immunobiology, effective immediately. Wed, 08 Mar 2023 04:00:00 Z https://medicine.yale.edu/news-article/yale-led-trial-shows-significant-disease-free-survival-for-patients-diagnosed-with-non-small-cell-lung-cancer/ https://medicine.yale.edu/news-article/yale-led-trial-shows-significant-disease-free-survival-for-patients-diagnosed-with-non-small-cell-lung-cancer/ The new data show there are ongoing benefits for patients taking osimertinib, including prolonged disease-free survival (DFS) over placebo, reduced risk of local and distant metastases (spread of tumor), and improved central nervous system DFS. Wed, 01 Feb 2023 04:00:00 Z https://medicine.yale.edu/news-article/study-finds-large-gap-in-breast-cancer-treatment-recommendations-for-patients-aged-70-vs-69/ https://medicine.yale.edu/news-article/study-finds-large-gap-in-breast-cancer-treatment-recommendations-for-patients-aged-70-vs-69/ Age-based heuristics can lead to large differences in breast cancer treatment based on small differences in chronologic age, according to a new analysis of more than 500,000 patient records. Wed, 01 Feb 2023 04:00:00 Z https://medicine.yale.edu/news-article/older-patients-left-behind-in-progress-against-lung-cancer-yale-study-shows/ https://medicine.yale.edu/news-article/older-patients-left-behind-in-progress-against-lung-cancer-yale-study-shows/ Although widespread use of immune checkpoint inhibitors (ICIs) in patients with advanced lung cancer has led to meaningful improvements in survival in younger patients, older patients have not experienced similar survival benefits, new research from Yale Cancer Center shows. The study was published in JAMA Oncology. Thu, 26 Jan 2023 04:00:00 Z https://medicine.yale.edu/news-article/yale-scientists-enable-massively-parallel-dna-insertions-into-human-cells/ https://medicine.yale.edu/news-article/yale-scientists-enable-massively-parallel-dna-insertions-into-human-cells/ Yale Cancer Center scientists have developed a novel technology that for the first time enables massively parallel DNA substitutions (known as “knock-ins”) into human cells by taking advantage of messenger RNA (mRNA), a platform now well-known from its use as the COVID vaccine vehicle. Thu, 26 Jan 2023 04:00:00 Z https://seas.yale.edu/news-events/news/discovery-oxygens-role-growth-tumors-reconsidered https://seas.yale.edu/news-events/news/discovery-oxygens-role-growth-tumors-reconsidered Yale researchers have made a discovery that changes conventional thinking about the role that oxygen plays in the growth of tumors—an area of cancer research that has been intensely studied in recent years. Fri, 16 Dec 2022 04:00:00 Z https://medicine.yale.edu/news-article/oncology-therapy-at-the-end-of-life-have-we-missed-the-mark/ https://medicine.yale.edu/news-article/oncology-therapy-at-the-end-of-life-have-we-missed-the-mark/ In a study published today in JAMA Oncology, researchers at Yale Cancer Center in collaboration with researchers from Flatiron Health, Inc., revealed that despite recommendations, aggressive cancer care at the end-of-life persists and there has been a substantial transition from the use of chemotherapy to immunotherapy. Fri, 21 Oct 2022 04:00:00 Z https://medicine.yale.edu/news-article/a-new-path-for-treating-brain-cancer-with-a-yale-developed-compound/ https://medicine.yale.edu/news-article/a-new-path-for-treating-brain-cancer-with-a-yale-developed-compound/ Yale researchers have developed a new class of molecules that target some of the deadliest brain cancers while sparing healthy tissue. The discovery combines innovative synthetic chemistry and cutting-edge mechanistic studies in molecular biology, and offers a potentially powerful new approach to treating drug-resistant glioma tumors. Thu, 28 Jul 2022 04:00:00 Z