2021
Surgical strategies for older patients with glioblastoma
Barak T, Vetsa S, Nadar A, Jin L, Gupte TP, Fomchenko EI, Miyagishima DF, Yalcin K, Vasandani S, Gorelick E, Zhao AY, Antonios J, Theriault BC, Lifton N, Marianayagam N, Omay B, Omay ZE, Huttner A, McGuone D, Blondin NA, Corbin Z, Fulbright RK, Moliterno J. Surgical strategies for older patients with glioblastoma. Journal Of Neuro-Oncology 2021, 155: 255-264. PMID: 34626296, PMCID: PMC8651607, DOI: 10.1007/s11060-021-03862-z.Peer-Reviewed Original ResearchConceptsKarnofsky performance scoreLength of surgeryOlder patientsOverall survivalPostoperative complicationsSurgical resectionSurgical strategyLow preoperative KPS scorePoor Karnofsky performance scoreLow Karnofsky performance scoreYale-New Haven HospitalPostoperative adjuvant treatmentPreoperative KPS scoreAdjuvant treatment regimensExtent of resectionNew Haven HospitalUse of ioMRIAdjuvant treatmentHospital stayKPS scoreMethodsClinical dataConsecutive patientsPrognostic factorsTreatment regimensExperienced hands
2020
Tumor Location and Treatment Modality are Associated with Overall Survival in Adult Medulloblastoma
K A, Freedman I, Lee JH, Miyagishima D, Ahmed O, Yeung J. Tumor Location and Treatment Modality are Associated with Overall Survival in Adult Medulloblastoma. Cureus 2020, 12: e7061. PMID: 32226663, PMCID: PMC7089624, DOI: 10.7759/cureus.7061.Peer-Reviewed Original ResearchTumor locationOverall survivalAdult medulloblastomaPrognostic factorsAdult casesTreatment modalitiesSurvival timeMultivariate Cox proportional hazards modelWorse median survival timeCox proportional hazards modelOverall median survivalSignificant prognostic factorsBetter overall survivalEnd Results registryMedian survival timeMultivariate survival analysisUnited States SurveillanceProportional hazards modelCourse of treatmentAggressive brain tumorYears of ageMedian survivalSEER registryShorter survivalClinical variables