Duman, Pothula: Cell-type speciﬁc modulation of NMDA receptors triggers antidepressant actions
In a new paper published in Molecular Psychiatry, Santosh Pothula, Post Doctoral Associate in the laboratory of Dr. Ronald S Duman, and the late Ronald Duman, PhD, Elizabeth Mears and House Jameson Professor of Psychiatry and Professor of Neuroscience, and Director of the Abraham Ribicoff Research Facilities, write that both the NMDA receptor (NMDAR) positive allosteric modulator (PAM), and antagonist, can exert rapid antidepressant effects as shown in several animal and human studies. However, how this bidirectional modulation of NMDARs causes similar antidepressant effects remains unknown.Source: Molecular Psychiatry
Yale's Colón-Ramos Energizes His Native Puerto Rico's Response to COVID-19
For years, Daniel Colón-Ramos, PhD, of Yale School of Medicine, has gathered knowledge and resources from Yale and around the world for the benefit of his native Puerto Rico. The COVID-19 pandemic has spurred him to do so again.
Elena Gracheva is a finalist of the 2020 Blavatnik National Awards for Young Scientists
Dr. Elena Gracheva, an Associate Professor of Cellular & Molecular Physiology and of Neuroscience, is a 2020 Finalists of the prestigious Blavatnik National Awards for Young Scientists, the world’s largest unrestricted prize for early-career scientists.Source: Elena Gracheva is a finalist of the 2020 Blavatnik National Awards for Young Scientists
Carefully, Yale Labs Stir to Life Across Campus
Since June 1, the start of a broad, three-phase reactivation of campus, an estimated 4,000 faculty members, graduate students, and staff representing more than 500 labs around Yale have fired up microscopes, opened fume hoods, or dusted off other essential research equipment.Source: YaleNews
Anthony Koleske Appointed Ensign Professor of MB&B and Neuroscience
Koleske, deputy dean for scientific affairs for the basic sciences, focuses his research on the molecular mechanisms by which growth factor and adhesion receptors regulate cell shape, structural stability, and movement.Source: YaleNews
Anthony Koleske appointed Ensign Professor of MB&B and Neuroscience
Anthony J. Koleske, newly named as the Ensign Professor of Molecular Biophysics and Biochemistry (MB&B) and of Neuroscience, studies the biochemical mechanisms that control changes in cell shape and movement in order to understand how these processes break down in cancer and brain diseases.Source: Yale News
Yale Engage COVID 19 Inflammation & Genetics, Where Biology Meets Translation
On June 3, 2020, nearly 350 industry representatives and academics joined the inaugural Yale Engage webinar series, Facilitating Collaboration to Combat COVID-19. Opening remarks were made by Michael Crair, PhD, the conversation was moderated by Ruth Montgomery, PhD, and the highly informative panelists included Akiko Iwasaki, PhD, Ellen Foxman, MD, PhD, Naftali Kaminski, MD, Carrie Lucas, PhD, Andrew Wang, MD, PhD. If you were unable to attend, or if you missed a portion of the webinar, please find a link to the recording below, along with a PDF of the panelists’ presentations.
Yale Researchers Find Where Stress Lives
Yale researchers have found a neural home of the feeling of stress people experience, an insight that may help people deal with the debilitating sense of fear and anxiety that stress can evoke, Yale researchers report May 27 in the journal Nature Communications.
New Imaging Tool Helps Researchers See Extent of Alzheimer’s Early Damage
New imaging technology allows scientists to see the widespread loss of brain synapses in early stages of Alzheimer’s disease, a finding that one day may aid in drug development, according to a new Yale University study.Source: Yale News
Here's Why You're So Exhausted, Despite Doing Less During the Coronavirus Pandemic — And How to Feel Better
Rajita Sinha, PhD, Foundations Fund Professor of Psychiatry and Professor in the Child Study Center and of Neuroscience and Director of the Yale Stress Center, spoke to Yahoo Life about the impact of stress on the body during the COVID-19 crisis.Source: Yahoo Life
Ni Feng receives a 2020 Warren Alpert Distinguished Scholar Award
Ni Fend, a postdoctoral researcher in Elena Gracheva's lab, has become a 2020 Warren Alpert Distinguished Scholar. Her project "Hanging in the Balance: Fluid Homeostasis in Hibernation" aims to reveal fundamental knowledge about how hibernation enables some species to survive over an entire winter without water. This project will use the thirteen-lined ground squirrel as a model system to dissect and manipulate the neural circuits that regulate fluid balance across torpor and arousal states during hibernation.Source: Ni Feng receives a 2020 Warren Alpert Distinguished Scholar award
Major Gift Will Support an Innovative Brain Research Collaboration
The Swiss-based NOMIS Foundation is making a large five-year award for research into what makes the human brain unique. The research will be a collaboration between the laboratories of James P. Noonan, PhD, associate professor of genetics and of neuroscience at Yale School of Medicine, and Franck Polleux, PhD, professor of neuroscience at Columbia University and a member of that school’s Zuckerman Institute. Their combined mission is to understand the brain and mind.
Two Yale MD-PhD Students Honored With Soros Fellowships for New Americans
Two Yale School of Medicine (YSM) MD-PhD students, Stefano Daniele (fifth-year) and Eric Hoyeon Song (fourth-year), are among the 30 new recipients of the Paul & Daisy Soros Fellowships for New Americans. The fellows, all of whom are immigrants or the children of immigrants, were selected from a record-breaking pool of over 2,200 applicants for their potential to make significant contributions to the United States.
New Deputy Dean for Scientific Affairs (Basic Science Departments) Is Named
Anthony J. Koleske, PhD, professor of molecular biophysics and biochemistry and neuroscience, assumes the role of deputy dean for scientific affairs (basic science departments) effective April 1, 2020. Koleske succeeds Michael Crair, PhD, William Ziegler III Professor of Neuroscience and professor of ophthalmology and visual science, who steps into the role of Yale University's vice provost for research.
In Isolation, Worries and Stress are Magnified
Marc Potenza, MD, PhD, Professor of Psychiatry, in the Child Study Center and of Neuroscience, speaks about the coronavirus quarantine and the difficulty for people who suffer from substance use disorder, gambling addiction, or problematic video gaming—otherwise known as Internet gaming disorder.Source: Medical Xpress
Stress and Resilience Town Halls
Beginning Friday, March 20, the Department of Psychiatry will offer virtual “Stress and Resilience town halls” over Zoom that are open to all faculty, residents, students, and staff at Yale School of Medicine and Yale New Haven Health. Virtual meetings will take place twice daily and run for up to an hour. Individuals can attend as frequently as they like.