Junjie Guo, PhD

Assistant Professor of Neuroscience

Departments & Organizations

Center for RNA Science and Medicine

Interdepartmental Neuroscience Program

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS) | Molecular Cell Biology, Genetics and Development | Neuroscience: Neural Disorders

Yale Medicine Outlist


A native of Guangzhou, China, Junjie Guo received his B.A. in Biology from Peking University (Beijing). He completed his Ph.D. thesis in the Solomon H. Snyder Department of Neuroscience at Johns Hopkins University School of Medicine, working with Hongjun Song on neuronal DNA methylation in the adult brain. During his postdoctoral training in David Bartel's laboratory at the Whitehead Institute/MIT,  Guo developed a series of high-throughput computational and experimental methods to investigate circular RNAs and intracellular RNA folding. He joined the Department of Neuroscience at Yale School of Medicine in Fall 2017. 

The Guo lab is broadly interested in questions at the intersection of RNA biology and neuroscience, with an emphasis on developing and applying new tools to investigate RNA-based gene regulatory mechanisms in the nervous system. Research in the lab aims to understand how these mechanisms may be specialized in the nervous system as well as their roles in neurological diseases.

Education & Training

PhD Johns Hopkins University School of Medicine, Neuroscience (2011)
BA Peking University, Biology (2006)
Postdoctoral Fellow Whitehead Institute/MIT/HHMI

Honors & Recognition

  • NIH Director's New Innovator (DP2) AwardNIH Common Fund (2018)

  • NARSAD Young InvestigatorBrain & Behavior Research Foundation (2018)

  • Klingenstein-Simons Fellowship Award in NeuroscienceThe Klingenstein Fund and the Simons Foundation (2018)

  • Yale Scholar in Neurodegenerative ResearchYale School of Medicine (2017)

  • Damon Runyon Postdoctoral FellowshipDamon Runyon Cancer Research Foundation (2013)

  • Peter and Patricia Gruber International Research Award in NeuroscienceSociety for Neuroscience, the Gruber Foundation (2012)

  • Harold M. Weintraub Graduate Student AwardFred Hutchinson Cancer Research Center (2012)

Professional Service

  • American Society for Cell Biology (2017 - Present)

  • RNA Society (2017 - Present)

  • Society for Neuroscience (2012 - Present)

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Contact Info

Junjie Guo, PhD
Mailing Address
Boyer Center for Molecular Medicine
295 Congress Ave. Room 154B

New Haven, CT 06519

Guo Laboratory