2014
Primary hypertrophic osteoarthropathy caused by homozygous deletion in HPGD gene in a family: changing clinical and radiological findings with long-term follow-up
Tüysüz B, Yılmaz S, Kasapçopur Ö, Erener-Ercan T, Ceyhun E, Bilguvar K, Günel M. Primary hypertrophic osteoarthropathy caused by homozygous deletion in HPGD gene in a family: changing clinical and radiological findings with long-term follow-up. Rheumatology International 2014, 34: 1539-1544. PMID: 24816859, DOI: 10.1007/s00296-014-3037-8.Peer-Reviewed Original ResearchConceptsRadiological findingsClinical findingsDigital clubbingHPGD geneYears of agePrimary hypertrophic osteoarthropathyMonths of ageHomozygous deletionPainful swellingHypertrophic osteoarthropathyInfantile periodPalmoplantar hyperkeratosisHand radiographsOssification defectsHomozygous mutationIntrafamilial variabilityLate childhoodAgePatientsClubbingMonthsFindingsSiblingsExon 3Years
2008
Therapeutic efficacy of Ac-DMQD-CHO, a caspase 3 inhibitor, for rat spinal cord injury
Akdemir O, Berksoy I, Karaoğlan A, Barut Ş, Bilguvar K, Çirakoğlu B, Şahan E, Çolak A. Therapeutic efficacy of Ac-DMQD-CHO, a caspase 3 inhibitor, for rat spinal cord injury. Journal Of Clinical Neuroscience 2008, 15: 672-678. PMID: 18378144, DOI: 10.1016/j.jocn.2007.06.014.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCord injuryGroup 2Therapeutic efficacyRat spinal cord injuryDiffuse hemorrhagic necrosisSpinal cord traumaGroup 3 ratsPolymorphonuclear leukocyte infiltrationCaspase-3 inhibitorCord traumaFunctional recoveryLeukocyte infiltrationLight microscopy examinationHemorrhagic necrosisNeurologic performanceFunctional outcomeSpinal cordRat modelTraumatic injuryVascular thrombiTreatment responseGroup 3InjuryThoracic region