2015
Intravenous Fibrinolytic Therapy in Central Retinal Artery Occlusion: A Patient-Level Meta-analysis
Schrag M, Youn T, Schindler J, Kirshner H, Greer D. Intravenous Fibrinolytic Therapy in Central Retinal Artery Occlusion: A Patient-Level Meta-analysis. JAMA Neurology 2015, 72: 1148-1154. PMID: 26258861, DOI: 10.1001/jamaneurol.2015.1578.Peer-Reviewed Original ResearchConceptsCentral retinal artery occlusionRetinal artery occlusionSystemic fibrinolytic therapyVisual acuity outcomesPatient-level dataNatural history groupConservative treatmentFibrinolytic therapyArtery occlusionAcuity outcomesPatient-Level Meta-AnalysisIntravenous fibrinolytic therapyAnterior chamber paracentesisAbsolute risk reductionOutcome of treatmentNatural history studiesTissue plasminogen activatorRandom-effects modelRelevant review articlesWeb of ScienceFibrinolysis treatmentConservative therapyRetinal ischemiaVisual outcomeConservative modalities
2013
Tissue plasminogen activator via cross-collateralization for tandem internal carotid and middle cerebral artery occlusion.
Bulsara KR, Ediriwickrema A, Pepper J, Robertson F, Aruny J, Schindler J. Tissue plasminogen activator via cross-collateralization for tandem internal carotid and middle cerebral artery occlusion. World Journal Of Clinical Cases 2013, 1: 290-4. PMID: 24364024, PMCID: PMC3868713, DOI: 10.12998/wjcc.v1.i9.290.Peer-Reviewed Original ResearchTissue plasminogen activatorMiddle cerebral artery occlusionTandem internal carotidCerebral artery occlusionArtery occlusionInternal carotidIntra-arterial tissue plasminogen activatorPlasminogen activatorEndovascular carotid stentingFurther embolic eventsHealth Stroke ScaleSystemic thrombolysisCarotid dissectionStroke ScaleEmbolic eventsCarotid stentingPoor outcomeCurrent treatmentHigh riskFull recoveryNational InstituteCarotidDissectionOcclusionFurther support
2012
Acute Central Retinal Artery Occlusion Treated with Intravenous Recombinant Tissue Plasminogen Activator
Nowak RJ, Amin H, Robeson K, Schindler JL. Acute Central Retinal Artery Occlusion Treated with Intravenous Recombinant Tissue Plasminogen Activator. Journal Of Stroke And Cerebrovascular Diseases 2012, 21: 913.e5-913.e8. PMID: 22349707, DOI: 10.1016/j.jstrokecerebrovasdis.2012.01.003.Peer-Reviewed Original ResearchConceptsCentral retinal artery occlusionAcute central retinal artery occlusionIntravenous recombinant tissue plasminogen activatorRecombinant tissue plasminogen activatorRetinal artery occlusionTissue plasminogen activatorMacular edemaArtery occlusionSymptom onsetLeft eyeVisual acuityRt-PACases of CRAOAcute ischemic cerebral strokePlasminogen activatorIntravenous rt-PALeft afferent pupillaryIschemic cerebral strokeProspective clinical trialsEffective therapeutic optionCherry-red spotRight-handed manMinimal visual acuityCurrent literatureAfferent pupillary