2020
Initial Stroke Evaluation
Amin H, Schindler J. Initial Stroke Evaluation. 2020, 5-9. DOI: 10.1007/978-3-030-52552-1_2.ChaptersStroke evaluationLarge vessel occlusionAcute stroke evaluationIntra-cerebral hemorrhageIntravenous thrombolysisStroke neurologistsEmergency departmentPhysical examinationVessel occlusionEmergency physiciansCT scanPatientsTimely assessmentSystematic evaluationThrombectomyThrombolysisHemorrhageNeurologistsEvaluationNursesPhysiciansOcclusion
2018
Safety Outcomes of Thrombolysis for Acute Ischemic Stroke in Patients with History of Intracranial Hemorrhage (P4.033)
Chu S, Sommaruga S, Hwang D, Dearborn J, Sansing L, Cord B, Samarth G, Petersen N, Gilmore E, Schindler J, Matouk C, Sheth K, Falcone G. Safety Outcomes of Thrombolysis for Acute Ischemic Stroke in Patients with History of Intracranial Hemorrhage (P4.033). Neurology 2018, 90 DOI: 10.1212/wnl.90.15_supplement.p4.033.Peer-Reviewed Original Research
2016
Initial Stroke Evaluation
Amin H, Schindler J. Initial Stroke Evaluation. 2016, 5-8. DOI: 10.1007/978-3-319-39605-7_2.ChaptersValidation of TURN, a simple predictor of symptomatic intracerebral hemorrhage after IV thrombolysis
Asuzu D, Nystrӧm K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Validation of TURN, a simple predictor of symptomatic intracerebral hemorrhage after IV thrombolysis. Clinical Neurology And Neurosurgery 2016, 146: 71-75. PMID: 27152469, DOI: 10.1016/j.clineuro.2016.04.017.Peer-Reviewed Original ResearchConceptsSymptomatic intracerebral hemorrhageIntracerebral hemorrhageRt-PAOdds ratioYale-New Haven HospitalNINDS rt-PA trialIschemic stroke patientsNew Haven HospitalTwo-sample t-testStroke patientsCharacteristic curveThrombolysisHemorrhageSignificant differencesPatientsT-testScoresExternal datasetSimple predictorInternal datasetHospital
2015
TURN Score Predicts 24-Hour Cerebral Edema After IV Thrombolysis
Asuzu D, Nyström K, Sreekrishnan A, Schindler J, Wira C, Greer D, Halliday J, Kimberly WT, Sheth KN. TURN Score Predicts 24-Hour Cerebral Edema After IV Thrombolysis. Neurocritical Care 2015, 24: 381-388. PMID: 26341364, DOI: 10.1007/s12028-015-0198-6.Peer-Reviewed Original ResearchConceptsSymptomatic intracerebral hemorrhageBrain swellingIntracerebral hemorrhageCerebral edemaPoor outcomeSevere outcomesOdds ratioLogistic regression reporting odds ratiosNINDS rt-PA trialIschemic stroke patientsReporting odds ratioNew brainNew onsetMidline shiftStroke patientsRt-PAEdemaThrombolysisMortalityOutcomesMass effectCharacteristic curveHemorrhagePatientsStatistical associationTURN: A Simple Predictor of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis
Asuzu D, Nyström K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. TURN: A Simple Predictor of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis. Neurocritical Care 2015, 23: 166-171. PMID: 25869481, DOI: 10.1007/s12028-015-0131-z.Peer-Reviewed Original ResearchConceptsSymptomatic intracerebral hemorrhageBaseline NIHSS scorePrestroke mRS scoreNIHSS scoreMRS scoreIntracerebral hemorrhageRt-PAOdds ratioYale-New Haven HospitalNINDS rt-PA trialIschemic stroke patientsIschemic stroke treatmentIndependent predictorsStroke treatmentStroke patientsClinical parametersPlatelet countHyperacute strokeDerivation datasetThrombolysisLogistic regressionSubstantial riskNew scoreCharacteristic curveHemorrhageComparison of On-hour vs Off-hour Patient Cohorts at a Primary Stroke Center: Onset-To-Treatment Duration and Clinical Outcomes after IV Thrombolysis (S21.005)
Nystrom K, Asuzu D, Amin H, Schindler J, Wira C, Greer D, Chi N, Halliday J, Sheth K. Comparison of On-hour vs Off-hour Patient Cohorts at a Primary Stroke Center: Onset-To-Treatment Duration and Clinical Outcomes after IV Thrombolysis (S21.005). Neurology 2015, 84 DOI: 10.1212/wnl.84.14_supplement.s21.005.Peer-Reviewed Original Research
2014
HAT Score Outperforms 7 Other Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis (P3.109)
Asuzu D, Nystrom K, Halliday J, Wira C, Greer D, Schindler J, Sheth K. HAT Score Outperforms 7 Other Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis (P3.109). Neurology 2014, 82 DOI: 10.1212/wnl.82.10_supplement.p3.109.Peer-Reviewed Original Research