2021
Functional Reserve: The Residual Variance in Instrumental Activities of Daily Living Not Explained by Brain Structure, Cognition, and Demographics
Kraal A, Massimo L, Fletcher E, Carrión C, Medina L, Mungas D, Gavett B, Farias S. Functional Reserve: The Residual Variance in Instrumental Activities of Daily Living Not Explained by Brain Structure, Cognition, and Demographics. Neuropsychology 2021, 35: 19-32. PMID: 33393797, PMCID: PMC8753970, DOI: 10.1037/neu0000705.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overApathyBrainCognitionCognitive DysfunctionCognitive ReserveDementiaDemographyDisease ProgressionFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingMaleMiddle AgedNervous System DiseasesNeuropsychological TestsPsychiatric Status Rating ScalesConceptsBrain structuresDementia severityLate-life cognitive outcomesAssociation of cognitionModifiable intervention targetsInstrumental Activities of DailyCognitively normal individualsCognitive reserveCognitive performanceStructural equation modelingInstrumental activitiesActivities of DailyCognitive outcomesEnhanced functional reserveCognitive declineCognitionIntervention targetsBrain atrophyBrain pathologyLawton-Brody Instrumental ActivitiesOlder adultsEquation modelingPreliminary validationApathyLongitudinal data
2020
Education differentially contributes to cognitive reserve across racial/ethnic groups
Avila JF, Rentería MA, Jones RN, Vonk JMJ, Turney I, Sol K, Seblova D, Arias F, Hill‐Jarrett T, Levy S, Meyer O, Racine AM, Tom SE, Melrose RJ, Deters K, Medina LD, Carrión CI, Díaz‐Santos M, Byrd DR, Chesebro A, Colon J, Igwe KC, Maas B, Brickman AM, Schupf N, Mayeux R, Manly JJ. Education differentially contributes to cognitive reserve across racial/ethnic groups. Alzheimer's & Dementia 2020, 17: 70-80. PMID: 32827354, PMCID: PMC8376080, DOI: 10.1002/alz.12176.Peer-Reviewed Original ResearchConceptsWashington Heights-Inwood Columbia Aging ProjectCognitive reserveGrowth curve modelingEducational attainmentStructural magnetic resonance imagingLanguage performanceLanguage trajectoriesLanguage declineCurve modelingAging ProjectHigher educational attainmentMemoryCortical thinningEthnic groupsWMH burdenAttainmentMagnetic resonance imagingNegative impactResonance imagingRace/ethnicity
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