Clinical Neuroscience Grand Rounds - Ron Riesenburger, MD

Password: 956762

Meeting ID: 942 1952 3099

Program Objective(s): 

1. Wild-type Transthyretun amyloid (ATTRwt) is the specific amyloid associated with ligamentum flavum thickening 
2. The amyloid triad consists of spinal stenosis, carpal tunnel syndrome, cardiac amyloidosis
3. Literature shows ligamentum flavum is thicker in patients with amyloid vs. no amyloid deposition
4. Literature shows a dose-dependent relationship between amyloid load and ligamentum flavum thickness. In other words, the more amyloid, the thicker the ligamentum flavum
5. Much more research is required. If causation between amyloid deposition and ligamentum flavum thickening is "proven," then medicinal treatment of spinal stenosis may become a possible treatment