Yale Center for Restless Legs Syndrome

The Yale Center for Restless Legs Syndrome (YCRLS) within the Yale Departments of Neurology and Pulmonary, Critical Care, & Sleep Medicine are comprised of physicians and scientists dedicated to the recognition, evaluation, treatment, and understanding of restless legs syndrome (RLS). The group consists of physicians with differing backgrounds which include neurology, sleep medicine, and psychiatry. The primary goal of YCRLS is to provide excellent care for persons suffering from sensory, motor, psychologic, and sleep symptoms related to RLS.

The Yale Center for Restless Legs Syndrome is one of eight RLS Quality Care Centers in the world recognized and supported by the RLS Foundation. In addition, to expertise in RLS, practitioners in this center, have expertise in the assessment and treatment of sleep-disordered breathing, depression, and insomnia, conditions that are comorbid with RLS. Through the Yale Centers for Sleep Medicine, there is access to polysomnography, and through Yale Departments of Neurology and Radiology, there is access to neuroimaging. Treatment strategies include the use of the most up-to-date medications. In addition, within the same complex, there is an infusion center, where intravenous iron can be administered.

The other mission of the Yale Center for Restless Legs Syndrome is to increase understanding of RLS through investigation of this disorder.  We have ongoing clinical trials that patients may have the option of participating in. We are an active teaching center and provide learning opportunities to medical students, residents of neurology and internal medicine, and fellows in movement disorders, sleep medicine, and pulmonary medicine.  

Bio Profile

Brian B. Koo, MD

Associate Professor

Director, Sleep Medicine Laboratory at Connecticut Veterans Affairs Healthcare System, Medicine

Director, Yale Center for Restless Legs Syndrome

     A graduate of the University of Pennsylvania (BA, 1995) and Tufts University School of Medicine (MD, 2001), Dr. Koo joined the Case Western Reserve School of Medicine faculty in 2008 and was subsequently recruited to Yale University in 2013. Dr. Koo’s primary clinical and research interests lie at the intersection between neurology and sleep medicine, in both of which he is board certified. Dr. Koo is particularly interested in the restless legs syndrome (RLS) and periodic limb movements...

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Bio Profile

Vahid Mohsenin, MD

Professor of Medicine (Pulmonary)

Senior Fellow, The John B. Pierce Laboratory

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At the Yale Center for Restless Legs Syndrome, we are committed not only to treating patients with RLS but also to understanding the disease and to optimizing treatment strategies. For this reason, we are involved in research to clarify the underlying biological mechanisms of RLS. We are also involved in clinical trials in the treatment of RLS. If you interested in learning more about this research, you can contact Dr. Brian Koo at brian.koo@yale.edu.

We are also accepting donations to help us carry out this work. If you are interested in giving a donation, please contact Sharon McManus at (203) 436-8543 or contact her at Sharon.mcmanus@yale.edu. Please mention donations to the Yale Center for Restless Legs Syndrome.

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We evaluate and treat children with dystonia, chorea, myoclonus, tremor, motor tics, stereotypies and other paroxysmal disorders of movement.

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