2017
Glucose Outcomes with the In-Home Use of a Hybrid Closed-Loop Insulin Delivery System in Adolescents and Adults with Type 1 Diabetes
Garg SK, Weinzimer SA, Tamborlane WV, Buckingham BA, Bode BW, Bailey TS, Brazg RL, Ilany J, Slover RH, Anderson SM, Bergenstal RM, Grosman B, Roy A, Cordero TL, Shin J, Lee SW, Kaufman FR. Glucose Outcomes with the In-Home Use of a Hybrid Closed-Loop Insulin Delivery System in Adolescents and Adults with Type 1 Diabetes. Diabetes Technology & Therapeutics 2017, 19: 155-163. PMID: 28134564, PMCID: PMC5359676, DOI: 10.1089/dia.2016.0421.Peer-Reviewed Original ResearchConceptsHybrid closed-loop insulin delivery systemGlucose valuesDiabetic ketoacidosis eventsMulticenter pivotal trialStudy phaseBlood sample testingType 1 diabetesClosed-loop insulin delivery systemBlood glucose valuesHome useContinuous glucose monitoringSensor glucose valuesHCl therapyKetoacidosis eventsHybrid closed-loop systemPivotal trialsInsulin delivery systemsGlucose outcomesMedtronic MiniMedType 1Glucose monitoringInsulin deliveryAdultsStayAdolescents
2016
Stress and Coping Predicts Adjustment and Glycemic Control in Adolescents with Type 1 Diabetes
Jaser SS, Patel N, Xu M, Tamborlane WV, Grey M. Stress and Coping Predicts Adjustment and Glycemic Control in Adolescents with Type 1 Diabetes. Annals Of Behavioral Medicine 2016, 51: 30-38. PMID: 27496164, PMCID: PMC5253083, DOI: 10.1007/s12160-016-9825-5.Peer-Reviewed Original ResearchConceptsDiabetes-related stressQuality of lifeType 1 diabetesGlycemic controlSymptoms of depressionDepressive symptomsMedical chartsDiabetesSymptomsType 1Coping strategiesPrimary control copingSignificant predictorsAdolescentsDisengagement coping strategiesMonthsPoor qualityDepressionOutcomesAdolescent usePredictorsCharacteristics of youth with type 1 diabetes (T1D) with and without a parent with T1D in the T1D exchange clinic registry
Fox LA, Mubasher M, Wolfsdorf JI, Buckingham BA, Peters AL, Tamborlane WV, Schatz DA, Maahs DM, Miller KM, Beck RW, Network F. Characteristics of youth with type 1 diabetes (T1D) with and without a parent with T1D in the T1D exchange clinic registry. Journal Of Diabetes 2016, 8: 834-838. PMID: 26663683, DOI: 10.1111/1753-0407.12363.Peer-Reviewed Original ResearchConceptsType 1 diabetesDiabetic ketoacidosisT1D Exchange Clinic RegistryInsulin pump therapyT1D Exchange RegistryContinuous glucose monitoringAcute complicationsGlycemic controlSevere hypoglycemiaClinic registryPump therapyPresent studyDiabetes managementT1D.T1DStudy participantsGlucose monitoringLinear mixed modelsDiabetesRegistryCharacteristics of youthChildrenAdolescentsMixed modelsStatistical comparison
2015
Testing for Rewards: A Pilot Study to Improve Type 1 Diabetes Management in Adolescents
Petry NM, Cengiz E, Wagner JA, Weyman K, Tichy E, Tamborlane WV. Testing for Rewards: A Pilot Study to Improve Type 1 Diabetes Management in Adolescents. Diabetes Care 2015, 38: 1952-1954. PMID: 26203061, PMCID: PMC4580608, DOI: 10.2337/dc15-0765.Peer-Reviewed Original Research
2012
Insulin Therapy in Children and Adolescents
Tamborlane WV, Sikes KA. Insulin Therapy in Children and Adolescents. Endocrinology And Metabolism Clinics Of North America 2012, 41: 145-160. PMID: 22575411, DOI: 10.1016/j.ecl.2012.01.002.Peer-Reviewed Original ResearchConceptsMultiple daily injectionsContinuous insulin infusionInsulin therapyBasal-bolus therapyMainstay of treatmentInsulin replacement therapyType 2 diabetesType 1 diabetesDaily injectionsReplacement therapyAnalogue insulinInsulin infusionInsulin secretionBiosynthetic humanTherapyInsulin formulationsNormal patternDiabetesTreatmentChildrenAdolescentsInfusionAimMainstayInsulin
2005
Single‐ and Multiple‐Dose Pharmacokinetics of Pioglitazone in Adolescents With Type 2 Diabetes
Christensen ML, Meibohm B, Capparelli EV, Velasquez‐Mieyer P, Burghen GA, Tamborlane WV. Single‐ and Multiple‐Dose Pharmacokinetics of Pioglitazone in Adolescents With Type 2 Diabetes. The Journal Of Clinical Pharmacology 2005, 45: 1137-1144. PMID: 16172178, DOI: 10.1177/0091270005279578.Peer-Reviewed Original ResearchConceptsMultiple-dose pharmacokineticsType 2 diabetesMultiple dosingDoses of pioglitazoneDaily dose administrationTotal serum concentrationsLast doseFirst doseSystemic exposureDose administrationSerum concentrationsBlood samplesPioglitazoneDose levelsActive metaboliteDosingDoseDiabetesPharmacokineticsAdolescentsHoursActive compoundsAdministrationDoses
2002
Depression in Type 1 diabetes in children Natural history and correlates
Grey M, Whittemore R, Tamborlane W. Depression in Type 1 diabetes in children Natural history and correlates. Journal Of Psychosomatic Research 2002, 53: 907-911. PMID: 12377302, DOI: 10.1016/s0022-3999(02)00312-4.Peer-Reviewed Original Research