2014
Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram
DeVito EE, Babuscio TA, Nich C, Ball SA, Carroll KM. Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram. Drug And Alcohol Dependence 2014, 145: 156-167. PMID: 25457739, PMCID: PMC4268325, DOI: 10.1016/j.drugalcdep.2014.10.007.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsClinical trialsClinical outcomesTreatment outcomesCocaine dependenceBehavioral therapyBehavioral treatment conditionsPoor treatment outcomesEvidence-based treatmentsGender differencesWidespread clinical implementationPoor outcomePharmacological treatmentMedication conditionAddiction pharmacotherapyCocaine useSecondary analysisBehavioral treatmentClinical implementationWomenCareful assessmentDisulfiramOutcomesTrialsMenA pilot trial of a videogame-based exercise program for methadone maintained patients
Cutter CJ, Schottenfeld RS, Moore BA, Ball SA, Beitel M, Savant JD, Stults-Kolehmainen MA, Doucette C, Barry DT. A pilot trial of a videogame-based exercise program for methadone maintained patients. Journal Of Substance Use And Addiction Treatment 2014, 47: 299-305. PMID: 25012555, PMCID: PMC4487635, DOI: 10.1016/j.jsat.2014.05.007.Peer-Reviewed Original ResearchConceptsExercise interventionSubstance useSubstance use disorder treatmentMethadone-maintained patientsStudy completion ratesPhysical activity levelsGreater physical activityWii Fit PlusUse disorder treatmentExercise programSedentary controlsPilot trialPhysical activityDisorder treatmentActive game playPilot studyActivity levelsInterventionPatientsCompletion ratesHigh satisfactionFurther investigationTrialsPsychological wellnessParticipantsComputer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone
Carroll KM, Kiluk BD, Nich C, Gordon MA, Portnoy GA, Marino DR, Ball SA. Computer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone. American Journal Of Psychiatry 2014, 171: 436-444. PMID: 24577287, PMCID: PMC4042674, DOI: 10.1176/appi.ajp.2013.13070987.Peer-Reviewed Original ResearchConceptsCocaine-dependent individualsCognitive behavioral therapyMethadone maintenanceCommunity-based outpatient clinicsPrevious pilot trialMethadone maintenance programStandard methadone maintenanceDisseminable strategyDefinitive trialOutpatient clinicClinical trialsEffective adjunctPilot trialTreatment terminationTreatment retentionBetter outcomesConsecutive weeksCBT4CBTWeekly accessAddiction treatmentDurable effectsTrialsSubstance usersStatistical significanceMethadone
2013
The Recovery Line: A pilot trial of automated, telephone-based treatment for continued drug use in methadone maintenance
Moore BA, Fazzino T, Barry DT, Fiellin DA, Cutter CJ, Schottenfeld RS, Ball SA. The Recovery Line: A pilot trial of automated, telephone-based treatment for continued drug use in methadone maintenance. Journal Of Substance Use And Addiction Treatment 2013, 45: 63-69. PMID: 23375114, PMCID: PMC3642223, DOI: 10.1016/j.jsat.2012.12.011.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultAutomationCocaine-Related DisordersFeasibility StudiesFemaleHumansMaleMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPatient Acceptance of Health CarePatient SatisfactionPilot ProjectsSubstance Abuse DetectionTelephoneTherapy, Computer-AssistedConceptsMethadone maintenanceLarge clinical trialsTelephone-based treatmentCurrent pilot studyPatient satisfactionClinical trialsPatient utilizationComputer-based treatmentPilot trialInitial efficacyInteractive voice response systemDrug usePatientsScreen outcomesVoice response systemPilot studyIllicit drugsTreatmentDaily useTrialsEfficacyOpioidsAbstinenceRecovery lineCocaine
2011
Mutual influence in therapist competence and adherence to motivational enhancement therapy
Imel ZE, Baer JS, Martino S, Ball SA, Carroll KM. Mutual influence in therapist competence and adherence to motivational enhancement therapy. Drug And Alcohol Dependence 2011, 115: 229-236. PMID: 21227601, PMCID: PMC3397170, DOI: 10.1016/j.drugalcdep.2010.11.010.Peer-Reviewed Original ResearchMeSH KeywordsBehavior, AddictiveClinical CompetenceCounselingFemaleHealth PersonnelHumansMaleMotivationMulticenter Studies as TopicPatient Acceptance of Health CarePatient ComplianceProfessional CompetenceProfessional-Patient RelationsPsychotherapyRandomized Controlled Trials as TopicSeverity of Illness IndexTreatment OutcomeConceptsMotivational enhancement therapyClinical trialsTherapist adherenceEnhancement therapyMulti-site clinical trialLarge multi-site clinical trialDays of useTreatment protocolTherapists' caseloadsAdherenceTherapist competenceTrialsTherapist performanceClient severityTherapyCaseloadTherapistsThree-level multilevel models
2010
Informal discussions in substance abuse treatment sessions with Spanish-speaking clients
Bamatter W, Carroll KM, Añez LM, Paris M, Ball SA, Nich C, Frankforter TL, Suarez-Morales L, Szapocznik J, Martino S. Informal discussions in substance abuse treatment sessions with Spanish-speaking clients. Journal Of Substance Use And Addiction Treatment 2010, 39: 353-363. PMID: 20817381, PMCID: PMC2967664, DOI: 10.1016/j.jsat.2010.07.005.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapyStandard treatmentDrug Abuse Clinical Trials Network protocolTreatment sessionsSubstance abuse treatment outcomesSignificant inverse correlationHispanic clientsEarly treatment sessionsSession audiotapesTreatment outcomesSubstance abuse treatment sessionsEnhancement therapyClient motivationSubstance useInverse correlationTreatment fidelityNational InstituteTreatmentAdverse consequencesTrialsSessionsClient retentionMonolingual SpanishMultisite effectiveness trials of treatments for substance abuse and co-occurring problems: Have we chosen the best designs?
Nunes EV, Ball S, Booth R, Brigham G, Calsyn DA, Carroll K, Feaster DJ, Hien D, Hubbard RL, Ling W, Petry NM, Rotrosen J, Selzer J, Stitzer M, Tross S, Wakim P, Winhusen T, Woody G. Multisite effectiveness trials of treatments for substance abuse and co-occurring problems: Have we chosen the best designs? Journal Of Substance Use And Addiction Treatment 2010, 38: s97-s112. PMID: 20307801, PMCID: PMC2909698, DOI: 10.1016/j.jsat.2010.01.012.Peer-Reviewed Original ResearchMeSH KeywordsCommunity Health ServicesComparative Effectiveness ResearchEvidence-Based MedicineHumansInformation DisseminationNational Institute on Drug Abuse (U.S.)Randomized Controlled Trials as TopicResearch DesignSubstance Abuse Treatment CentersSubstance-Related DisordersTreatment OutcomeUnited StatesConceptsClinical Trials NetworkMultisite effectiveness trialEffectiveness trialNational Drug Abuse Treatment Clinical Trials NetworkSubstance abuseNew interventionsReal-world clinical settingNew treatment interventionsPrimary outcome paperFuture effectiveness trialHIV risk behaviorsEvidence-based treatmentsBehavioral health problemsCo-occurring problemsOutcome papersClinical trialsHIV riskTreatment interventionsHealth problemsRisk behaviorsClinical settingTrials NetworkDrug abuseTrialsSuch treatment
2009
A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users
Carroll KM, Martino S, Ball SA, Nich C, Frankforter T, Anez LM, Paris M, Suarez-Morales L, Szapocznik J, Miller WR, Rosa C, Matthews J, Farentinos C. A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users. Journal Of Consulting And Clinical Psychology 2009, 77: 993-999. PMID: 19803579, PMCID: PMC2792592, DOI: 10.1037/a0016489.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapyEnhancement therapySubstance useSubstance usersRandomized Effectiveness TrialIndividual sessionsCurrent substance useX time interactionTreatment condition interactionCondition x time interactionSubstance use problemsClinical trialsEffectiveness trialTreatment exposureTherapy phaseTreatment retentionTreatment sessionsHispanic adultsTherapyHeterogeneous groupHispanic individualsTime interactionIndividual treatmentTrialsUse problems
2008
Serious Adverse Events in Randomized Psychosocial Treatment Studies: Safety or Arbitrary Edicts?
Petry NM, Roll JM, Rounsaville BJ, Ball SA, Stitzer M, Peirce JM, Blaine J, Kirby KC, McCarty D, Carroll KM. Serious Adverse Events in Randomized Psychosocial Treatment Studies: Safety or Arbitrary Edicts? Journal Of Consulting And Clinical Psychology 2008, 76: 1076-1082. PMID: 19045975, PMCID: PMC2756150, DOI: 10.1037/a0013679.Peer-Reviewed Original ResearchConceptsSerious adverse eventsAdverse eventsStandard careDrug Abuse Clinical Trials NetworkMore (95% CI 4 to 167 more) serious adverse eventsSAE incidence rateClinical Trials NetworkPsychosocial treatment studiesPsychosocial intervention studiesPercent of participantsPsychosocial trialsIncidence ratePharmaceutical trialsTherapy trialsIntervention studiesTreatment studiesTrials NetworkHuman subjects protection policiesSubstance-abusing participantsContingency managementMotivational enhancementNational InstituteTrialsSignificant differencesCareWhat is usual about “treatment-as-usual”? Data from two multisite effectiveness trials
Santa Ana EJ, Martino S, Ball SA, Nich C, Frankforter TL, Carroll KM. What is usual about “treatment-as-usual”? Data from two multisite effectiveness trials. Journal Of Substance Use And Addiction Treatment 2008, 35: 369-379. PMID: 18337053, PMCID: PMC2712113, DOI: 10.1016/j.jsat.2008.01.003.Peer-Reviewed Original ResearchConceptsEffectiveness trialDrug Abuse Clinical Trials NetworkSubstance useMultisite effectiveness trialClinical Trials NetworkStandard clinical practiceParticipants' substance useCommunity-based drug abuse treatmentDrug abuse treatmentNumber of interventionsSubstance use outcomesPatient outcomesClinical practiceTrials NetworkAbuse treatmentUse outcomesNational InstituteSocial functioningTreatmentTrialsOpen-ended questionsOutcomesStandard practiceEarly stagesEarly sessions
2007
Site Matters: Multisite Randomized Trial of Motivational Enhancement Therapy in Community Drug Abuse Clinics
Ball SA, Martino S, Nich C, Frankforter TL, Van Horn D, Crits-Christoph P, Woody GE, Obert JL, Farentinos C, Carroll KM. Site Matters: Multisite Randomized Trial of Motivational Enhancement Therapy in Community Drug Abuse Clinics. Journal Of Consulting And Clinical Psychology 2007, 75: 556-567. PMID: 17663610, PMCID: PMC2148493, DOI: 10.1037/0022-006x.75.4.556.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapySubstance useEnhancement therapyBrief intervention conditionsOutpatient substance abuse programsSubstance use reductionDrug abuse clinicsSubstance abuse programsSession audiotapesRandomized trialsClinical trialsMultisite Randomized TrialSustained reductionTherapy phaseDrug usersPrimary alcohol usersAlcohol usersAbuse programsIntervention conditionSignificant increaseTherapyTrialsCAUOutpatientsClinicIssues in Designing and Implementing a Spanish‐Language Multi‐Site Clinical Trial
Suarez‐Morales L, Matthews J, Martino S, Ball SA, Rosa C, Farentinos C, Szapocznik J, Carroll KM. Issues in Designing and Implementing a Spanish‐Language Multi‐Site Clinical Trial. American Journal On Addictions 2007, 16: 206-215. PMID: 17612825, PMCID: PMC3628724, DOI: 10.1080/10550490701375707.Peer-Reviewed Original ResearchConceptsClinical trialsMulti-site clinical trialClinical Trials NetworkNIDA Clinical Trials NetworkMotivational enhancement therapySubstance abuse treatmentMulti-site trialClinical staffHealth disparitiesTrials NetworkAbuse treatmentEnhancement therapyTrialsHispanic populationStudy teamAssessment instrumentsDiverse populationsPopulationTherapy
2004
Millon Clinical Multiaxial Inventory-III Subtypes of Opioid Dependence: Validity and Matching to Behavioral Therapies
Ball SA, Nich C, Rounsaville BJ, Eagan D, Carroll KM. Millon Clinical Multiaxial Inventory-III Subtypes of Opioid Dependence: Validity and Matching to Behavioral Therapies. Journal Of Consulting And Clinical Psychology 2004, 72: 698-711. PMID: 15301655, PMCID: PMC3709250, DOI: 10.1037/0022-006x.72.4.698.Peer-Reviewed Original ResearchConceptsLess symptom improvementOpioid-dependent outpatientsOpioid dependenceSymptom improvementClinical trialsBetter outcomesPredictive validity analysesBehavioral therapyVoucher conditionSubtypesAffective disturbancesIntervention conditionMatching AnalysisPredictive validityCounselingValidity analysisNaltrexoneGroup counselingOutpatientsTherapyTrials