Poojith Nuthalapati
Postdoctoral AssociateAbout
Research
Publications
2025
Synaptic Pathology in Traumatic Brain Injury and Therapeutic Insights
Nuthalapati P, Holmes S, Altalib H, Fesharaki-Zadeh A. Synaptic Pathology in Traumatic Brain Injury and Therapeutic Insights. International Journal Of Molecular Sciences 2025, 26: 9604. PMID: 41096867, PMCID: PMC12525020, DOI: 10.3390/ijms26199604.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryChronic phaseImpact of traumatic brain injuryBrain injuryDendritic spinesImpaired synaptic plasticityLong-term impacts of TBIAcute phaseLoss of dendritic spinesSynaptic dysfunctionPhase of traumatic brain injuryGABAergic disruptionMemory deficitsNeurotransmitter systemsAcute phase of traumatic brain injuryDevelopment of post-traumatic epilepsyMood disturbancePost-TBISynaptic plasticityPost-traumatic epilepsyNeurological sequelaeExcitotoxic injurySynaptic densitySynaptic pathologyCerebral edemaInfluence of Exercise on Oxygen Consumption, Pulmonary Ventilation, and Blood Gas Analyses in Individuals with Chronic Diseases
Korivi M, Ghanta M, Nuthalapati P, Natesh N, Tang J, Bhaskar L. Influence of Exercise on Oxygen Consumption, Pulmonary Ventilation, and Blood Gas Analyses in Individuals with Chronic Diseases. Life 2025, 15: 1255. PMID: 40868903, PMCID: PMC12387642, DOI: 10.3390/life15081255.Peer-Reviewed Original ResearchPhysical activityVigorous-intensity physical activityWorld Health OrganizationEffects of exercise trainingBalance-training exercisesNon-pharmacological interventionsInfluence of exerciseHeightened metabolic demandsMuscle-strengtheningOxygen consumptionResistance trainingAerobic exerciseExercise trainingModerate-intensityLifestyle factorsIndividual life expectancyOlder adultsCardiopulmonary healthHealthcare systemType 2 diabetesChronic diseasesPulmonary ventilationExercisePsychological issuesBody compositionExamining psychiatric and cognitive adverse effects of brivaracetam, clobazam, lacosamide, eslicarbazepine, and perampanel in a veteran population
Nuthalapati P, DeBonis D, Gopaul M, Okafor C, Orner M, Jimenez A, Altalib H. Examining psychiatric and cognitive adverse effects of brivaracetam, clobazam, lacosamide, eslicarbazepine, and perampanel in a veteran population. Epilepsy & Behavior 2025, 172: 110557. PMID: 40570732, DOI: 10.1016/j.yebeh.2025.110557.Peer-Reviewed Original ResearchVeteran populationRetrospective analysis of veteransPopulation of veteransAnalysis of veteransICD-10 codesPsychiatric adverse effectsAnti-seizure medicinesVA systemICD-10Neurology noteMale participantsVeteransCognitive adverse effectsSafety analyticsIntegrated programCognitive disordersAdverse effectsORQ1-Q3Treatment initiationChronic neurological disorderExercise cautionEffects of brivaracetamPopulationMedian ageBiosensing Technologies to Improve Neurological Disease Management
Nuthalapati P, Singh A, Desai B, Yendapalli P, Gongireddy R, Singh K, Bollu B, Pinninty D. Biosensing Technologies to Improve Neurological Disease Management. 2025, 401-421. DOI: 10.1002/9781394287697.ch13.Peer-Reviewed Original ResearchCenobamate and pregnancy: A-single level 4 epilepsy center experience
Jimenez A, Toghramadjian I, Okafor C, Hanin A, Zhou X, Dorotan M, Nuthalapati P, Sakya S, Hirsch L, Altalib H, Lazorwitz A, Herlopian A. Cenobamate and pregnancy: A-single level 4 epilepsy center experience. Epilepsy & Behavior 2025, 169: 110440. PMID: 40318387, DOI: 10.1016/j.yebeh.2025.110440.Peer-Reviewed Original ResearchConceptsConcentration-to-dose ratioPost-partum periodUnintended pregnancyContraceptive methodsSingle-center retrospective chart reviewFemales of childbearing ageEarly-term birthPrevent unintended pregnancyAdult female patientsDrug level monitoringMonths of agePre-conceptual counsellingElective terminationSpontaneous miscarriagePregnancy outcomesCongenital malformationsFemale patientsHormonal contraceptionChildbearing ageMedical comorbiditiesCenobamatePregnancyContraceptive usePharmacokinetic profilePatientsReview Article: Efficacy and Safety of JNK Inhibitors in Cancer Therapy.
Sahithi L, Nuthalapati P, Hussain M, Nagabhishek S, Umeza B, Santoshi R, Afzal K, Ghanta M. Review Article: Efficacy and Safety of JNK Inhibitors in Cancer Therapy. Critical Reviews™ In Oncogenesis 2025, 30: 91-108. PMID: 41275483, DOI: 10.1615/critrevoncog.2025060497.Peer-Reviewed Original Research
2024
Phytochemical compounds for treating hyperuricemia associated with gout: a systematic review
Chenchula S, Ghanta M, Alhammadi M, Mohammed A, Anitha K, Nuthalapati P, Raju G, Huh Y, Bhaskar L. Phytochemical compounds for treating hyperuricemia associated with gout: a systematic review. Naunyn-Schmiedeberg's Archives Of Pharmacology 2024, 398: 4779-4801. PMID: 39636406, DOI: 10.1007/s00210-024-03686-4.Peer-Reviewed Original ResearchEx Vivo Immunization: A Strategy for Immunization Against SARS-CoV-2
Singh H, Nuthalapati P, Yendapalli P, Sahu D. Ex Vivo Immunization: A Strategy for Immunization Against SARS-CoV-2. 2024, 258-271. DOI: 10.1039/bk9781837672813-00258.Peer-Reviewed Original ResearchPeripheral blood mononuclear cellsNatural killer cellsCell-mediated immunityBlood mononuclear cellsEnhanced immune responseNaive lymphocytesDendritic cellsKiller cellsT cellsAntigen presentationB cellsMononuclear cellsImmune responseSARS-nCoV-2Human hostSignaling cascadesSARS-CoV-2Global pandemic coronavirus diseaseVirion particlesImmunityMass immunizationAdverse effectsCoronavirus 2Pandemic coronavirus diseaseNeuroinvasion by SARS-CoV-2 Influences the Prognosis of Neurological Disorders
Nuthalapati P, Ghanta M, Farran B, Chenchula S, Vedam V, Pukalendiran V, Amerneni K, Bhaskar L. Neuroinvasion by SARS-CoV-2 Influences the Prognosis of Neurological Disorders. 2024, 272-308. DOI: 10.1039/bk9781837672813-00272.Peer-Reviewed Original ResearchInterventional Brain Medicine: Medicine's newest frontier
Nuthalapati P, Palmer C, Barbosa D, George M, Brown J. Interventional Brain Medicine: Medicine's newest frontier. Brain Medicine 2024, 1: 3-5. DOI: 10.61373/bm024g.0013.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Get In Touch
Contacts
Mailing Address
Yale School of Medicine
2 Church St South
New Haven, Connecticut 06519
United States