1997
Sodium-hydrogen exchange isoform expression in blood cells: implications for studies in diabetes mellitus
Rutherford P, Pizzonia J, Abu-Alfa A, Biemesderfer D, Reilly R, Aronson P. Sodium-hydrogen exchange isoform expression in blood cells: implications for studies in diabetes mellitus. Experimental And Clinical Endocrinology & Diabetes 1997, 105: 13-16. PMID: 9288535, DOI: 10.1055/s-0029-1211787.Peer-Reviewed Original ResearchConceptsPeripheral blood cellsPeripheral blood cell preparationsDiabetes mellitusBlood cell preparationsBlood cellsNHE activityPathophysiological roleNa-H exchange activityNHE-1Vascular smooth muscle cell proliferationNHE-3Smooth muscle cell proliferationProgressive renal impairmentNHE isoformsVascular smooth muscleDirect pathophysiological roleCell preparationsMuscle cell proliferationPlatelet membranesNa-H exchangeRenal proximal tubulesNHE isoforms 1Sodium-hydrogen exchangeRenal impairmentNondiabetic controls
1991
Na+-H+ Exchanger and Its Role in Essential Hypertension and Diabetes Mellitus
Huot S, Aronson P. Na+-H+ Exchanger and Its Role in Essential Hypertension and Diabetes Mellitus. Diabetes Care 1991, 14: 521-535. PMID: 1650693, DOI: 10.2337/diacare.14.6.521.Commentaries, Editorials and LettersConceptsDiabetes mellitusEssential hypertensionInsulin-dependent diabetes mellitusHigh blood pressureSubgroup of patientsBlood pressureHypertensionAnimal modelsPathophysiological statesTransepithelial absorptionAltered activityCellular mechanismsMellitusPatientsIntracellular pHPossible roleCell volume regulationVolume regulationCell growthRecent cDNA cloningNephropathyUbiquitous transport systems