2001
Use of cryopreserved cadaveric vein allograft for hemodialysis access precludes kidney transplantation because of allosensitization
Benedetto B, Lipkowitz G, Madden R, Kurbanov A, Hull D, Miller M, Bow L. Use of cryopreserved cadaveric vein allograft for hemodialysis access precludes kidney transplantation because of allosensitization. Journal Of Vascular Surgery 2001, 34: 139-142. PMID: 11436087, DOI: 10.1067/mva.2001.114206.Peer-Reviewed Original ResearchConceptsVein allograftsHemodialysis accessPRA valuesControl cohortPRA assaysWaiting listKidney transplantation waiting listPanel-reactive antibodies valuesPotential kidney transplant recipientsUniversity-affiliated medical centerMajor histocompatibility complex IKidney transplant recipientsHistory of transfusionTransplant waiting listTransplantation waiting listMean PRANonimmunosuppressed individualsHemodialysis populationKidney transplantationPrior transplantationTransplant recipientsConsecutive patientsProsthetic graftsAntibody valuesKidney failure
1996
Organ transplantation at the Hartford Transplant Center.
Schweizer R, Bartus S, Hull D, Perdrizet G, Swanson M, Low H, Gallagher R, Dougherty J, Rosson R, Hyams J, D'Avella J, Rasoulpour M, Sullivan P, Bow L. Organ transplantation at the Hartford Transplant Center. Connecticut Medicine 1996, 60: 387-93. PMID: 8758656.Peer-Reviewed Original ResearchConceptsTransplant centersActuarial graft survivalRecipients of kidneysMost transplant centersTwo-year survivalHealth care communityTriple immunosuppressionGraft survivalKidney transplantationLiver transplantRelated donorsCadaveric kidneysHigh success rateDonor organsOrgan transplantationOrgan transplantsPancreas patientsKidneySuccess rateSurvivalTransplantationTransplantNational averageHeartImmunosuppression
1995
Enhanced intracoronary thrombolysis with urokinase using a novel, local drug delivery system. In vitro, in vivo, and clinical studies.
Mitchel J, Fram D, Palme D, Foster R, Hirst J, Azrin M, Bow L, Eldin A, Waters D, McKay R. Enhanced intracoronary thrombolysis with urokinase using a novel, local drug delivery system. In vitro, in vivo, and clinical studies. Circulation 1995, 91: 785-93. PMID: 7828307, DOI: 10.1161/01.cir.91.3.785.Peer-Reviewed Original ResearchConceptsDispatch catheterLocal infusionEnd-hole catheterU urokinaseCatheter infusionIntracoronary thrombusAngioplasty siteUrokinase administrationLocal drug delivery systemIntracoronary thrombolysisUrokinase infusionBalloon angioplastySystemic bolusIntramural depositionNew local drug delivery systemDistal coronary flowLocal urokinase deliveryLocal urokinase infusionThrombus-containing stenosesConventional balloon angioplastyInfusion of urokinaseInfusion of salinePorcine coronary arteriesSystemic fibrinolytic stateCardiac catheterization laboratory
1994
Inhibition of platelet deposition and lysis of intracoronary thrombus during balloon angioplasty using urokinase-coated hydrogel balloons.
Mitchel J, Azrin M, Fram D, Hong M, Wong S, Barry J, Bow L, Curley T, Kiernan F, Waters D. Inhibition of platelet deposition and lysis of intracoronary thrombus during balloon angioplasty using urokinase-coated hydrogel balloons. Circulation 1994, 90: 1979-1988. PMID: 7923688, DOI: 10.1161/01.cir.90.4.1979.Peer-Reviewed Original ResearchConceptsLocal urokinase deliveryVivo balloon angioplastyIntracoronary thrombusBalloon angioplastyPlatelet depositionThrombotic closureDistal embolizationAngioplasty siteAbrupt closureArterial wallHydrogel balloonContralateral control arteriesContralateral control vesselsIntramural drug deliveryVivo studiesConventional balloon angioplastyNew Zealand rabbitsU urokinaseConventional angioplastyBalloon dilatationClinical efficacyReflow phenomenonIliac arteryBlood exposureControl arteries