2022
Benefits of weight loss of 10% or more in patients with overweight or obesity: A review
Tahrani AA, Morton J. Benefits of weight loss of 10% or more in patients with overweight or obesity: A review. Obesity 2022, 30: 802-840. PMID: 35333446, DOI: 10.1002/oby.23371.Peer-Reviewed Original ResearchConceptsObesity-related complicationsModest weight lossWeight lossBariatric surgeryLarge weight lossReduced cancer riskWeight-related complicationsCardiovascular risk factorsHealth-related qualityWeight management programType 2 diabetesGreater weight lossMain treatment targetsCost-effective interventionLifestyle modificationLifestyle interventionSevere obesityKnee osteoarthritisSleep apneaRisk factorsCancer riskGlucose metabolismPatientsOverweightTreatment targets
2020
Correlating actual one-year weight loss with predicted weight loss by the MBSAQIP: bariatric surgical risk/benefit calculator
Zhou R, Ying L, Valle J, Moore J, Nadzam G, Roberts K, Ghiassi S, Morton J, Duffy A. Correlating actual one-year weight loss with predicted weight loss by the MBSAQIP: bariatric surgical risk/benefit calculator. Surgical Endoscopy 2020, 35: 5705-5708. PMID: 32968922, DOI: 10.1007/s00464-020-08030-4.Peer-Reviewed Original ResearchConceptsHigher preoperative BMIBariatric surgeryWeight lossActual weight lossPreoperative BMIOne-year weight lossYale-New Haven HospitalNational databasePatient preoperative informationMethodsA retrospective reviewBody mass indexBackgroundThe American SocietyNew Haven HospitalUnpaired t-testObese patientsPatient factorsRetrospective reviewMass indexPreoperative discussionPreoperative informationBMI pointsBMIPatientsInformed consentSurgerySafety and Efficacy of Bariatric and Metabolic Surgery
Ghiassi S, Morton JM. Safety and Efficacy of Bariatric and Metabolic Surgery. Current Obesity Reports 2020, 9: 159-164. PMID: 32253662, DOI: 10.1007/s13679-020-00377-y.Peer-Reviewed Original ResearchConceptsDurable weight lossBariatric surgeryRisk/benefit ratioWeight lossRisk of complicationsCurrent medical treatmentRisk of mortalityObesity-related diseasesReviewBariatric surgeryBariatric proceduresCause morbidityMetabolic surgeryObesity comorbiditiesMedical managementRelated comorbiditiesSafety profileCardiovascular diseaseGlobal prevalenceMedical treatmentSurgeryBenefit ratioMortalityComorbiditiesMorbidityDurable methodEffect of JumpstartMD, a Commercial Low-Calorie Low-Carbohydrate Physician-Supervised Weight Loss Program, on 22,407 Adults
Bourke S, Morton JM, Williams P. Effect of JumpstartMD, a Commercial Low-Calorie Low-Carbohydrate Physician-Supervised Weight Loss Program, on 22,407 Adults. Journal Of Obesity 2020, 2020: 8026016. PMID: 32318289, PMCID: PMC7157789, DOI: 10.1155/2020/8026016.Peer-Reviewed Original ResearchConceptsWeight loss programGreater weight lossWeight lossLoss programWeekly appointmentsCommercial weight loss programEffective weight lossPharmacologic treatmentLow carbohydrate foodsMeal replacementReplacement dietLast observationCompletersMajor determinantWomenDietLonger enrollmentAppointmentsPatientsCoach meetingsMonths
2019
Concerning Greater Social Contexts in Bariatric Surgery Availability and Telomere Length Outcomes—Reply
Morton J, Garg T, Leva N. Concerning Greater Social Contexts in Bariatric Surgery Availability and Telomere Length Outcomes—Reply. JAMA Surgery 2019, 154: 884-884. PMID: 31188413, DOI: 10.1001/jamasurg.2019.1727.Peer-Reviewed Original ResearchAssessment of obesity prevalence and validity of obesity diagnoses coded in claims data for selected surgical populations
Ammann EM, Kalsekar I, Yoo A, Scamuffa R, Hsiao CW, Stokes AC, Morton JM, Johnston SS. Assessment of obesity prevalence and validity of obesity diagnoses coded in claims data for selected surgical populations. Medicine 2019, 98: e16438. PMID: 31335698, PMCID: PMC6709187, DOI: 10.1097/md.0000000000016438.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedArthroplasty, Replacement, KneeBariatric SurgeryBody Mass IndexCatheter AblationClinical CodingElectronic Health RecordsFemaleHerniorrhaphyHumansMaleMiddle AgedObesityOutcome Assessment, Health CarePatient SelectionPrevalencePrognosisReproducibility of ResultsRetrospective StudiesUnited StatesConceptsBody mass indexPositive predictive valueBariatric surgeryDiagnosis codesElectronic health recordsSurgical populationClaims dataHernia repairObesity diagnosisPrognostic factorsSurgical outcomesInterpretation of studiesCardiac ablationPatient body mass indexMeasured body mass indexHigh positive predictive valueImportant prognostic factorType of surgeryAdministrative healthcare dataAdministrative claims dataFalse positive patientsPatient ageMass indexPatient selectionIndex procedureObesity Disease Pandemic on Joint Disease and Longevity
Milla C, Lo Menzo E, Morton J, Rosenthal RJ. Obesity Disease Pandemic on Joint Disease and Longevity. The Journal Of Arthroplasty 2019, 34: s33-s35. PMID: 30954412, DOI: 10.1016/j.arth.2019.03.004.Peer-Reviewed Original Research
2018
Strategies for Weight Reduction Prior to Total Joint Arthroplasty.
Chen MJ, Bhowmick S, Beseler L, Schneider KL, Kahan SI, Morton JM, Goodman SB, Amanatullah DF. Strategies for Weight Reduction Prior to Total Joint Arthroplasty. Journal Of Bone And Joint Surgery 2018, 100: 1888-1896. PMID: 30399084, DOI: 10.2106/jbjs.18.00020.Peer-Reviewed Original ResearchRecommendations on the most suitable quality‐of‐life measurement instruments for bariatric and body contouring surgery: a systematic review
de Vries C, Kalff M, Prinsen C, Coulman K, Haan C, Welbourn R, Blazeby J, Morton J, van Wagensveld B. Recommendations on the most suitable quality‐of‐life measurement instruments for bariatric and body contouring surgery: a systematic review. Obesity Reviews 2018, 19: 1395-1411. PMID: 29883059, DOI: 10.1111/obr.12710.Peer-Reviewed Original ResearchConceptsBariatric surgerySystematic reviewCochrane database systematic reviewsPatient-reported outcome measuresHealth Measurement INstruments (COSMIN) checklistLife measurement instrumentsFuture clinical trialsMeasurement propertiesSystematic literature searchDegree of recommendationFurther validation studiesClinical trialsEligible studiesOutcome measuresLife instrumentsMethodological qualityLiterature searchSurgeryLife measurementsContent validityStrong evidencePoor qualityValidation studyEMBASEReview
2017
American Society for Metabolic and Bariatric Surgery estimation of metabolic and bariatric procedures performed in the United States in 2016
English WJ, DeMaria EJ, Brethauer SA, Mattar SG, Rosenthal RJ, Morton JM. American Society for Metabolic and Bariatric Surgery estimation of metabolic and bariatric procedures performed in the United States in 2016. Surgery For Obesity And Related Diseases 2017, 14: 259-263. PMID: 29370995, DOI: 10.1016/j.soard.2017.12.013.Peer-Reviewed Original ResearchConceptsBariatric proceduresQuality Improvement ProgramBariatric surgeryNational Surgical Quality Improvement ProgramBariatric Outcomes Longitudinal DatabaseSurgical Quality Improvement ProgramIntragastric balloon placementBariatric Surgery AccreditationObesity treatment interventionsNationwide Inpatient SampleDuodenal switch procedureAmerican SocietyNumber of proceduresMorbid obesityBiliopancreatic diversionGastric bypassAppropriate therapyUndergo surgeryBalloon placementInpatient SampleOutpatient centerSwitch procedureRevision proceduresTreatment interventionsSurgeryAmerican Society of Clinical Oncology Summit on Addressing Obesity Through Multidisciplinary Provider Collaboration: Key Findings and Recommendations for Action
Ligibel JA, Alfano CM, Hershman DL, Merrill JK, Basen‐Engquist K, Bloomgarden ZT, Demark‐Wahnefried W, Dixon S, Hassink SG, Jakicic JM, Morton JM, Okwuosa TM, Powell‐Wiley T, Rothberg AE, Stephens M, Streett SE, Wild RA, Westman EA, Williams RJ, Wollins DS, Hudis CA. American Society of Clinical Oncology Summit on Addressing Obesity Through Multidisciplinary Provider Collaboration: Key Findings and Recommendations for Action. Obesity 2017, 25: s34-s39. PMID: 29086516, PMCID: PMC6724199, DOI: 10.1002/oby.21987.Peer-Reviewed Original ResearchConceptsHealth care provider communityProvider collaborationMultidisciplinary collaborationAmerican SocietySynopsis of recommendationsProvider communityOncology providersProvider educationObesity preventionObesity epidemicClinical OncologyObesitySummit attendeesIdentified prioritiesMalignancyCancerASCOOncologyObesity in America
Rosenthal RJ, Morton J, Brethauer S, Mattar S, De Maria E, Benz JK, Titus J, Sterrett D. Obesity in America. Surgery For Obesity And Related Diseases 2017, 13: 1643-1650. PMID: 28935198, DOI: 10.1016/j.soard.2017.08.002.Peer-Reviewed Original ResearchConceptsPrevalence of obesityDisease of obesityBest treatment modalityTreatment of obesityUS household populationConsequences of obesityGeneral US populationSerious health problemHIV infectionExcess weightObesity treatmentTreatment modalitiesTreatment optionsUniversity HospitalHeart diseaseObese AmericansEarly deathObesityHealth problemsUS populationMental illnessDiseaseWeight lossProbability-based panelOversamples of blacksQuality of Life After Bariatric Surgery
Mazer LM, Azagury DE, Morton JM. Quality of Life After Bariatric Surgery. Current Obesity Reports 2017, 6: 204-210. PMID: 28527103, DOI: 10.1007/s13679-017-0266-7.Peer-Reviewed Original ResearchConceptsQuality of lifeBariatric surgeryDefinition of QoLLife outcomesPatient-reported qualityLong-term QoLConsensus Conference StatementObesity resultsPhysical QoLCurrent evidenceReviewThe purposeSurgeryQoLConference StatementMental healthLasting improvementAbsence of consensusRecent findingsOutcomesInitial studySummaryObesityComorbiditiesFollowAdipose tissue macrophages impair preadipocyte differentiation in humans
Liu LF, Craig CM, Tolentino LL, Choi O, Morton J, Rivas H, Cushman SW, Engleman EG, McLaughlin T. Adipose tissue macrophages impair preadipocyte differentiation in humans. PLOS ONE 2017, 12: e0170728. PMID: 28151993, PMCID: PMC5289462, DOI: 10.1371/journal.pone.0170728.Peer-Reviewed Original ResearchConceptsImpaired adipocyte differentiationSystemic insulin resistanceInsulin resistanceAdipocyte differentiationPreadipocyte differentiationMacrophage removalImpaired preadipocyte differentiationProinflammatory immune cellsAdipose tissue inflammationAbsence of CD14Insulin-resistant humansAdipose tissue samplesOil Red ODifferentiation of preadipocytesBariatric surgeryProinflammatory cytokinesInflammatory cytokinesTissue inflammationImmune cellsCytokine secretionAdiponectin secretionAdipogenic gene expressionPhysiologic mechanismsAdipose tissueVAT adipocytesComparative effectiveness of primary bariatric operations in the United States
Sudan R, Maciejewski ML, Wilk AR, Nguyen NT, Ponce J, Morton JM. Comparative effectiveness of primary bariatric operations in the United States. Surgery For Obesity And Related Diseases 2017, 13: 826-834. PMID: 28236529, DOI: 10.1016/j.soard.2017.01.021.Peer-Reviewed Original ResearchConceptsBPD/DSPrimary bariatric operationsBariatric surgery centerBariatric operationsAdverse eventsSurgery centersBody mass index unitWeight lossCo-morbidity resolutionMore adverse eventsMultiple surgical centersSerious adverse eventsType 2 diabetesGreater weight lossLarge multisite cohortCurrent bariatric operationsT2D resolutionComorbidity resolutionBaseline characteristicsGastric bypassDuodenal switchSurgical centersInverse probability weightingMultisite cohortOdds ratio
2016
Ethnic Considerations for Metabolic Surgery
Morton JM. Ethnic Considerations for Metabolic Surgery. Diabetes Care 2016, 39: 949-953. PMID: 27222553, DOI: 10.2337/dc16-0413.Peer-Reviewed Original ResearchConceptsMetabolic surgerySurgery outcomesBurden of obesityDifferent ethnic groupsComorbidity remissionDiabetes variesInfluence of ethnicitySurgeryEthnic groupsEthnic disparitiesObesityHealth concernWeight lossSocioeconomic statusDiabetesOutcomesEthnicityRemissionComplicationsGroupEthnic considerationsFurther refinementEffect of Vagal Nerve Blockade on Moderate Obesity with an Obesity-Related Comorbid Condition: the ReCharge Study
Morton JM, Shah SN, Wolfe BM, Apovian CM, Miller CJ, Tweden KS, Billington CJ, Shikora SA. Effect of Vagal Nerve Blockade on Moderate Obesity with an Obesity-Related Comorbid Condition: the ReCharge Study. Obesity Surgery 2016, 26: 983-989. PMID: 27048437, PMCID: PMC4831996, DOI: 10.1007/s11695-016-2143-y.Peer-Reviewed Original ResearchConceptsObesity-related comorbid conditionsBody mass indexModerate obesityComorbid conditionsPercentage excess weight lossWeight lossImplant site painVagal nerve blockadeCommon adverse eventsExcess weight lossObesity-related comorbiditiesWeight management counselingType 2 diabetesGreater weight lossSite painAdverse eventsBlockade therapyPrespecified subgroupsSevere obesitySham deviceMass indexNerve blockadeSleep apneaSafety profileClinical trialsCovering bariatric surgery has minimal effect on insurance premium costs within the Affordable Care Act
English W, Williams B, Scott J, Morton J. Covering bariatric surgery has minimal effect on insurance premium costs within the Affordable Care Act. Surgery For Obesity And Related Diseases 2016, 12: 1045-1050. PMID: 27260649, DOI: 10.1016/j.soard.2016.03.011.Peer-Reviewed Original ResearchConceptsBariatric surgery coverageBariatric surgerySurgery coverageAffordable Care ActAverage monthly premiumCare ActState health exchangesEssential health benefitsMillions of AmericansSurgeryPublic Use FileMonthly premiumHealth benefitsHealth exchangesUse FileInsurance premium costsBenchmark plansCoverage levelsMinimal effectPremium costsLipids and bariatric procedures Part 2 of 2: scientific statement from the American Society for Metabolic and Bariatric Surgery (ASMBS), the National Lipid Association (NLA), and Obesity Medicine Association (OMA)1
Bays H, Kothari SN, Azagury DE, Morton JM, Nguyen NT, Jones PH, Jacobson TA, Cohen DE, Orringer C, Westman EC, Horn DB, Scinta W, Primack C. Lipids and bariatric procedures Part 2 of 2: scientific statement from the American Society for Metabolic and Bariatric Surgery (ASMBS), the National Lipid Association (NLA), and Obesity Medicine Association (OMA)1. Surgery For Obesity And Related Diseases 2016, 12: 468-495. PMID: 27050404, DOI: 10.1016/j.soard.2016.01.007.Peer-Reviewed Original ResearchConceptsNational Lipid AssociationObesity Medicine AssociationBariatric proceduresLipid levelsBariatric surgeryLipid effectsRisk factorsCardiovascular disease risk factorsMajor cardiovascular risk factorsCardiovascular risk factorsDisease risk factorsTissue lipid metabolismScientific statementAmerican SocietyClinical lipidologyGut hormonesImmune factorsLipid associationIntestinal microbiotaBile acidsLipid metabolismTrace element deficienciesSurgeryAssociationMetabolic
2015
Lipids and bariatric procedures part 1 of 2: Scientific statement from the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and Obesity Medicine Association: EXECUTIVE SUMMARY
Bays HE, Jones PH, Jacobson TA, Cohen DE, Orringer CE, Kothari S, Azagury DE, Morton J, Nguyen NT, Westman EC, Horn DB, Scinta W, Primack C. Lipids and bariatric procedures part 1 of 2: Scientific statement from the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and Obesity Medicine Association: EXECUTIVE SUMMARY. Journal Of Clinical Lipidology 2015, 10: 15-32. PMID: 26892119, DOI: 10.1016/j.jacl.2015.12.003.Peer-Reviewed Original ResearchConceptsNational Lipid AssociationObesity Medicine AssociationBariatric proceduresLipid levelsBariatric surgeryScientific statementCholesterol metabolismCardiovascular disease risk factorsDisease risk factorsBile acid metabolismAmerican SocietyLipid benefitsGut hormonesImmune factorsRisk factorsCardiovascular diseaseLipid associationIntestinal microbiotaEndocrine factorsBile acidsExecutive summaryLipid effectsTrace element deficienciesAcid metabolismObesity