2021
Bariatric-Metabolic Surgery Utilisation in Patients With and Without Diabetes: Data from the IFSO Global Registry 2015–2018
Welbourn R, Hollyman M, Kinsman R, Dixon J, Cohen R, Morton J, Ghaferi A, Higa K, Ottosson J, Pattou F, Al-Sabah S, Anvari M, Himpens J, Liem R, Våge V, Walton P, Brown W, Kow L. Bariatric-Metabolic Surgery Utilisation in Patients With and Without Diabetes: Data from the IFSO Global Registry 2015–2018. Obesity Surgery 2021, 31: 2391-2400. PMID: 33638756, PMCID: PMC8113173, DOI: 10.1007/s11695-021-05280-6.Peer-Reviewed Original ResearchConceptsBody mass indexType 2 diabetes mellitusMethodsCross-sectional analysisRates of T2DMBariatric-metabolic surgeryHigh rateGastric bypassPrimary surgerySleeve gastrectomyDiabetes mellitusMass indexGlobal RegistryBaseline ageNational registryInclusion criteriaT2DMType of operationPatientsOlder menWomenSurgeryRegistryMenHigher proportionCommon operation
2020
Results of COVID-minimal Surgical Pathway During Surge-phase of COVID-19 Pandemic
Boffa DJ, Judson BL, Billingsley KG, Del Rossi E, Hindinger K, Walters S, Ermer T, Ratner E, Mitchell MR, Laurans MS, Johnson DC, Yoo PS, Morton JM, Zurich HB, Davis K, Ahuja N. Results of COVID-minimal Surgical Pathway During Surge-phase of COVID-19 Pandemic. Annals Of Surgery 2020, 272: e316-e320. PMID: 33086321, PMCID: PMC7668334, DOI: 10.1097/sla.0000000000004455.Peer-Reviewed Original ResearchConceptsHospital-acquired COVID-19 infectionCOVID-19 infectionSurgical pathwayCOVID-19 hospital admissionsCOVID-19 pandemicCommon surgical indicationsUrgent cancer treatmentOutcomes of patientsCOVID-19 patientsCOVID-19 testingCOVID-19 positive peoplePathway patientsPostoperative periodTimely surgeryHospital admissionMedian ageSurgical indicationsUrgent operationMedian lengthCancer patientsGenitourinary tractEmergency roomBACKGROUND DATASurgical proceduresPatient statusEffect of JumpstartMD, a Commercial Low-Calorie Low-Carbohydrate Physician-Supervised Weight Loss Program, on 22,407 Adults
Bourke S, Morton JM, Williams P. Effect of JumpstartMD, a Commercial Low-Calorie Low-Carbohydrate Physician-Supervised Weight Loss Program, on 22,407 Adults. Journal Of Obesity 2020, 2020: 8026016. PMID: 32318289, PMCID: PMC7157789, DOI: 10.1155/2020/8026016.Peer-Reviewed Original ResearchConceptsWeight loss programGreater weight lossWeight lossLoss programWeekly appointmentsCommercial weight loss programEffective weight lossPharmacologic treatmentLow carbohydrate foodsMeal replacementReplacement dietLast observationCompletersMajor determinantWomenDietLonger enrollmentAppointmentsPatientsCoach meetingsMonths
2019
Employing Enhanced Recovery Goals in Bariatric Surgery (ENERGY): a national quality improvement project using the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program
Brethauer SA, Grieco A, Fraker T, Evans-Labok K, Smith A, McEvoy MD, Saber AA, Morton JM, Petrick A. Employing Enhanced Recovery Goals in Bariatric Surgery (ENERGY): a national quality improvement project using the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program. Surgery For Obesity And Related Diseases 2019, 15: 1977-1989. PMID: 31640906, DOI: 10.1016/j.soard.2019.08.024.Peer-Reviewed Original ResearchConceptsBariatric Surgery AccreditationLength of stayBariatric surgeryReoperation rateNational quality improvement projectBariatric Surgery projectPrimary bariatric procedureOverall adverse eventsBariatric surgery patientsEnhanced recovery pathwayEnhanced recovery protocolQuality improvement projectQuality Improvement ProgramFinal analytic sampleBariatric proceduresOverall morbidityAdverse eventsReadmission ratesSurgery patientsPrivate practice programsSignificant associationRecovery pathwaysSurgery projectAnalytic sampleProcess measuresAssessment of obesity prevalence and validity of obesity diagnoses coded in claims data for selected surgical populations
Ammann EM, Kalsekar I, Yoo A, Scamuffa R, Hsiao CW, Stokes AC, Morton JM, Johnston SS. Assessment of obesity prevalence and validity of obesity diagnoses coded in claims data for selected surgical populations. Medicine 2019, 98: e16438. PMID: 31335698, PMCID: PMC6709187, DOI: 10.1097/md.0000000000016438.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedArthroplasty, Replacement, KneeBariatric SurgeryBody Mass IndexCatheter AblationClinical CodingElectronic Health RecordsFemaleHerniorrhaphyHumansMaleMiddle AgedObesityOutcome Assessment, Health CarePatient SelectionPrevalencePrognosisReproducibility of ResultsRetrospective StudiesUnited StatesConceptsBody mass indexPositive predictive valueBariatric surgeryDiagnosis codesElectronic health recordsSurgical populationClaims dataHernia repairObesity diagnosisPrognostic factorsSurgical outcomesInterpretation of studiesCardiac ablationPatient body mass indexMeasured body mass indexHigh positive predictive valueImportant prognostic factorType of surgeryAdministrative healthcare dataAdministrative claims dataFalse positive patientsPatient ageMass indexPatient selectionIndex procedureUsing Machine Learning Applied to Real-World Healthcare Data for Predictive Analytics: An Applied Example in Bariatric Surgery
Johnston SS, Morton JM, Kalsekar I, Ammann EM, Hsiao CW, Reps J. Using Machine Learning Applied to Real-World Healthcare Data for Predictive Analytics: An Applied Example in Bariatric Surgery. Value In Health 2019, 22: 580-586. PMID: 31104738, DOI: 10.1016/j.jval.2019.01.011.Peer-Reviewed Original ResearchConceptsLarge US healthcare claims databasesLaparoscopic metabolic surgeryHealthcare claims databasesType 2 diabetesStudy inclusion criteriaLogistic regression modelsDays postindexMedication cessationBariatric surgeryMetabolic surgeryT2D diagnosisCessation ratesPatient selectionMedication treatmentClaims databaseInclusion criteriaTreatment responseDiscriminative accuracyPatientsExternal validationSurgeryRegression modelsHealthcare dataTreatmentUseful predictive modelsPreoperative weight loss: is waiting longer before bariatric surgery more effective?
Eng V, Garcia L, Khoury H, Morton J, Azagury D. Preoperative weight loss: is waiting longer before bariatric surgery more effective? Surgery For Obesity And Related Diseases 2019, 15: 951-957. PMID: 31104959, DOI: 10.1016/j.soard.2019.03.012.Peer-Reviewed Original ResearchConceptsBody mass indexWeight lossBariatric surgeryMass indexConsultation visitSupervised weight loss programAverage body mass indexPreoperative wait timeSleeve gastrectomy patientsGastric bypass patientsPostoperative weight lossRate of complicationsDelay of treatmentWeight loss programSingle academic institutionInitial consultation visitAdverse surgical eventsSignificant long-term benefitWait timePreoperative percentageGastrectomy patientsGastric bypassLaparoscopic RouxBypass patientsAdverse eventsAssociation of Laparoscopic Gastric Bypass Surgery With Telomere Length in Patients With Obesity
Morton JM, Garg T, Leva N. Association of Laparoscopic Gastric Bypass Surgery With Telomere Length in Patients With Obesity. JAMA Surgery 2019, 154: 266-268. PMID: 30566188, PMCID: PMC6439632, DOI: 10.1001/jamasurg.2018.4830.Peer-Reviewed Original ResearchThe Impact of Ethnicity on Metabolic Outcomes after Bariatric Surgery
Valencia A, Garcia LC, Morton J. The Impact of Ethnicity on Metabolic Outcomes after Bariatric Surgery. Journal Of Surgical Research 2019, 236: 345-351. PMID: 30694776, DOI: 10.1016/j.jss.2018.09.061.Peer-Reviewed Original ResearchConceptsBody mass indexBariatric surgeryMetabolic outcomesDiabetic outcomesOral medicationsBlack patientsMass indexAsian patientsLaparoscopic sleeve gastrectomy procedureType II diabetes mellitusSignificant metabolic improvementSimilar metabolic outcomesSleeve gastrectomy procedureMajority of patientsAsian patient populationSingle academic institutionEthnic minority patientsNon-Hispanic whitesDiabetes remissionDiabetes resolutionGastric bypassLaparoscopic RouxPostoperative visitDiabetes mellitusMetabolic improvement
2018
Association of Bariatric Surgery and National Medication Use
Morton JM, Ponce J, Malangone-Monaco E, Nguyen N. Association of Bariatric Surgery and National Medication Use. Journal Of The American College Of Surgeons 2018, 228: 171-179. PMID: 30453056, DOI: 10.1016/j.jamcollsurg.2018.10.021.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBariatric SurgeryCardiovascular AgentsDrug UtilizationFemaleHealth Care CostsHumansHypoglycemic AgentsLongitudinal StudiesMaleMatched-Pair AnalysisMiddle AgedObesity, MorbidPostoperative PeriodPropensity ScoreRetrospective StudiesUnited StatesYoung AdultConceptsNonsurgical control patientsBariatric surgical patientsControl patientsSurgical patientsMedication useControl groupSurgical groupPharmacy costsPropensity-matched control groupTruven Health Analytics MarketScan Commercial ClaimsBariatric surgical proceduresMarketScan Commercial ClaimsTotal pharmacy costsLower pharmacy costsNonsurgical control groupEnduring treatmentGastric bypassIndex dateBariatric surgeryObese patientsPostoperative periodSevere obesitySurgical cohortBariatric operationsEncounters DatabaseComorbidity Remission Following Intragastric Dual Balloon Placement
Garcia L, Vajanaphanich S, Morton JM. Comorbidity Remission Following Intragastric Dual Balloon Placement. Obesity Surgery 2018, 29: 353-355. PMID: 30382461, DOI: 10.1007/s11695-018-3564-6.Peer-Reviewed Original ResearchConceptsComorbidity remissionBalloon placementDual balloonWeight lossWeight loss 6Treatment of obesityEarly-stage obesityBalloon insertionBiochemical improvementBlood pressureSingle institutionLipid profileEfficacious interventionsDemographic dataPatientsRemissionObesityMonthsSignificant improvementBalloonBiochemical dataPlacementHeterogeneity of weight loss after gastric bypass, sleeve gastrectomy, and adjustable gastric banding
Azagury D, Mokhtari TE, Garcia L, Rosas US, Garg T, Rivas H, Morton J. Heterogeneity of weight loss after gastric bypass, sleeve gastrectomy, and adjustable gastric banding. Surgery 2018, 165: 565-570. PMID: 30316577, DOI: 10.1016/j.surg.2018.08.023.Peer-Reviewed Original ResearchConceptsLaparoscopic adjustable gastric bandingPercent excess weight lossAdjustable gastric bandingExcess weight lossLaparoscopic sleeve gastrectomySuccessful treatment effectGastric bandingLaparoscopic RouxGastric bypassSleeve gastrectomyOdds ratioWeight lossTreatment effectsMean percent excess weight lossLong-term weight lossLaparoscopic adjustable gastricBody mass indexSingle academic institutionSubstantial weight lossAdjustable gastricPostoperative BMIBariatric proceduresObese patientsConsecutive patientsMass indexChanges in Cerebral Cortical Thickness Related to Weight Loss Following Bariatric Surgery
Bohon C, Garcia LC, Morton JM. Changes in Cerebral Cortical Thickness Related to Weight Loss Following Bariatric Surgery. Obesity Surgery 2018, 28: 2578-2582. PMID: 29876838, PMCID: PMC6400222, DOI: 10.1007/s11695-018-3317-6.Peer-Reviewed Original ResearchConceptsCerebral cortical thicknessCortical thicknessBariatric surgeryWeight Loss Following Bariatric SurgeryGreater excess weight lossExcess weight lossCortical gray matterMagnetic resonance imaging dataBrain changesPatientsGray matterSurgeryWeight lossPreliminary evidenceNeurocognitive measuresFurther investigationMemory recallImaging dataPrevious studiesObesityGlobal measuresLarge sampleMonthsDoes Urinary Bisphenol-A Change after Bariatric Surgery?
Dambkowski CL, Garcia L, Leva N, Morton JM. Does Urinary Bisphenol-A Change after Bariatric Surgery? Journal Of The American College Of Surgeons 2018, 227: 232-237. PMID: 29753982, DOI: 10.1016/j.jamcollsurg.2018.04.033.Peer-Reviewed Original ResearchConceptsBariatric surgery patientsBPA excretionSurgery patientsInsulin resistanceHeavier patientsHighest volume chemicalsBPA levelsSurgical weight lossUrinary BPA excretionUrinary BPA levelsHigher urinary excretionSingle academic institutionT-testStudent's t-testAverage weightLighter patientsPostoperative urineUrinary bisphenolBariatric surgeryPostoperative dataHemoglobin A1cPatient weightUrinary excretionLaboratory valuesPatientsWhich postoperative complications matter most after bariatric surgery? Prioritizing quality improvement efforts to improve national outcomes
Daigle CR, Brethauer SA, Tu C, Petrick AT, Morton JM, Schauer PR, Aminian A. Which postoperative complications matter most after bariatric surgery? Prioritizing quality improvement efforts to improve national outcomes. Surgery For Obesity And Related Diseases 2018, 14: 652-657. PMID: 29503096, DOI: 10.1016/j.soard.2018.01.008.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnastomotic LeakBariatric SurgeryCritical CareFemaleHealth PrioritiesHumansMaleMiddle AgedPatient ReadmissionPostoperative ComplicationsPostoperative HemorrhageProspective StudiesReoperationRisk AssessmentSurgical Wound InfectionTreatment OutcomeUrinary Tract InfectionsVenous ThromboembolismConceptsPopulation attributable fractionBariatric surgeryAttributable fractionSpecific complicationsIntensive care unit admissionQuality Improvement Program databaseBariatric surgery complicationsPrimary bariatric procedureCare unit admissionEnd-organ dysfunctionAdjustable gastric bandingImprovement Program databaseBariatric Surgery AccreditationUrinary tract infectionParticipant Use FileKey clinical outcomesKey surgical outcomesQuality improvement effortsUnit admissionGastric bandingGastric bypassPostoperative complicationsSleeve gastrectomyAdverse eventsBariatric proceduresPrevalence and Risk Factors for Bariatric Surgery Readmissions
Berger ER, Huffman KM, Fraker T, Petrick AT, Brethauer SA, Hall BL, Ko CY, Morton JM. Prevalence and Risk Factors for Bariatric Surgery Readmissions. Annals Of Surgery 2018, 267: 122-131. PMID: 27849660, DOI: 10.1097/sla.0000000000002079.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBariatric SurgeryConfidence IntervalsFemaleFollow-Up StudiesHumansIncidenceLaparoscopyMaleMiddle AgedObesity, MorbidPatient ReadmissionPostoperative ComplicationsPrevalencePrognosisQuality ImprovementRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsUnited StatesYoung AdultConceptsLaparoscopic adjustable gastric bandingLaparoscopic sleeve gastrectomyPrimary bariatric surgeryBariatric surgeryReadmission ratesNutritional depletionPrimary laparoscopic adjustable gastric bandingAdjustable gastric bandingCurrent Procedural Terminology codesNational readmission ratesProcedural Terminology codesType of procedureRelated readmissionsAbdominal painGastric bandingGastric bypassLaparoscopic RouxSleeve gastrectomyAnastomotic leakPrimary outcomePrimary procedureRisk factorsCommon causeReadmissionLRYGB
2017
Obesity in America
Rosenthal RJ, Morton J, Brethauer S, Mattar S, De Maria E, Benz JK, Titus J, Sterrett D. Obesity in America. Surgery For Obesity And Related Diseases 2017, 13: 1643-1650. PMID: 28935198, DOI: 10.1016/j.soard.2017.08.002.Peer-Reviewed Original ResearchConceptsPrevalence of obesityDisease of obesityBest treatment modalityTreatment of obesityUS household populationConsequences of obesityGeneral US populationSerious health problemHIV infectionExcess weightObesity treatmentTreatment modalitiesTreatment optionsUniversity HospitalHeart diseaseObese AmericansEarly deathObesityHealth problemsUS populationMental illnessDiseaseWeight lossProbability-based panelOversamples of blacksA multidisciplinary approach to laparoscopic sleeve gastrectomy among multiethnic adolescents in the United States
Jaramillo JD, Snyder E, Farrales S, Stevens M, Wall JK, Chao S, Morton J, Pratt JS, Hammer L, Shepard WE, Bruzoni M. A multidisciplinary approach to laparoscopic sleeve gastrectomy among multiethnic adolescents in the United States. Journal Of Pediatric Surgery 2017, 52: 1606-1609. PMID: 28697852, DOI: 10.1016/j.jpedsurg.2017.06.021.Peer-Reviewed Original ResearchConceptsLaparoscopic sleeve gastrectomySleeve gastrectomyObese adolescentsPercent excess weight lossNonalcoholic fatty liver diseaseWeight lossComorbidity resolution rateMorbidly obese adolescentsResolution of comorbiditiesExcess weight lossExcess body weightSerious public health problemDescriptive case seriesFatty liver diseaseOccurrence of complicationsPublic health problemMorbid obesityProspective databaseSurgical complicationsPrimary outcomeCase seriesComorbid conditionsLiver diseaseRetrospective studyMean ageAdipose tissue macrophages impair preadipocyte differentiation in humans
Liu LF, Craig CM, Tolentino LL, Choi O, Morton J, Rivas H, Cushman SW, Engleman EG, McLaughlin T. Adipose tissue macrophages impair preadipocyte differentiation in humans. PLOS ONE 2017, 12: e0170728. PMID: 28151993, PMCID: PMC5289462, DOI: 10.1371/journal.pone.0170728.Peer-Reviewed Original ResearchConceptsImpaired adipocyte differentiationSystemic insulin resistanceInsulin resistanceAdipocyte differentiationPreadipocyte differentiationMacrophage removalImpaired preadipocyte differentiationProinflammatory immune cellsAdipose tissue inflammationAbsence of CD14Insulin-resistant humansAdipose tissue samplesOil Red ODifferentiation of preadipocytesBariatric surgeryProinflammatory cytokinesInflammatory cytokinesTissue inflammationImmune cellsCytokine secretionAdiponectin secretionAdipogenic gene expressionPhysiologic mechanismsAdipose tissueVAT adipocytesComparative effectiveness of primary bariatric operations in the United States
Sudan R, Maciejewski ML, Wilk AR, Nguyen NT, Ponce J, Morton JM. Comparative effectiveness of primary bariatric operations in the United States. Surgery For Obesity And Related Diseases 2017, 13: 826-834. PMID: 28236529, DOI: 10.1016/j.soard.2017.01.021.Peer-Reviewed Original ResearchConceptsBPD/DSPrimary bariatric operationsBariatric surgery centerBariatric operationsAdverse eventsSurgery centersBody mass index unitWeight lossCo-morbidity resolutionMore adverse eventsMultiple surgical centersSerious adverse eventsType 2 diabetesGreater weight lossLarge multisite cohortCurrent bariatric operationsT2D resolutionComorbidity resolutionBaseline characteristicsGastric bypassDuodenal switchSurgical centersInverse probability weightingMultisite cohortOdds ratio