2015
Ethanol Upregulates NMDA Receptor Subunit Gene Expression in Human Embryonic Stem Cell-Derived Cortical Neurons
Xiang Y, Kim KY, Gelernter J, Park IH, Zhang H. Ethanol Upregulates NMDA Receptor Subunit Gene Expression in Human Embryonic Stem Cell-Derived Cortical Neurons. PLOS ONE 2015, 10: e0134907. PMID: 26266540, PMCID: PMC4534442, DOI: 10.1371/journal.pone.0134907.Peer-Reviewed Original ResearchConceptsCortical neuronsReceptor subunit gene expressionNeuron-specific biomarkerReverse transcription-quantitative polymerase chain reactionNMDA receptor subunit gene expressionChronic alcohol consumptionHuman brain cellsAlcohol-responsive genesNMDA receptor genesCalcium channel activityLive human brainQuantitative polymerase chain reactionSubunit gene expressionWithdrawal treatmentPolymerase chain reactionExpression changesEthanol exposureAlcohol abuseMultiple comparison correctionBrain cellsGene expression alterationsAlcohol consumptionNeuronal functionAlcohol metabolismNeurons
2011
Variation in OPRM1 and Risk of Suicidal Behavior in Drug‐Dependent Individuals
Arias AJ, Chan G, Gelernter J, Farrer L, Kranzler HR. Variation in OPRM1 and Risk of Suicidal Behavior in Drug‐Dependent Individuals. American Journal On Addictions 2011, 21: 5-10. PMID: 22211341, PMCID: PMC3674102, DOI: 10.1111/j.1521-0391.2011.00195.x.Peer-Reviewed Original Research